ID G5B6M7_HETGA Unreviewed; 342 AA.
AC G5B6M7;
DT 14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2011, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE SubName: Full=Sorting nexin-15 {ECO:0000313|EMBL:EHB04904.1, ECO:0000313|EMBL:JAN99972.1};
GN Name=SNX15 {ECO:0000313|EMBL:JAN99972.1};
GN ORFNames=GW7_20649 {ECO:0000313|EMBL:EHB04904.1};
OS Heterocephalus glaber (Naked mole rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae;
OC Heterocephalus.
OX NCBI_TaxID=10181 {ECO:0000313|EMBL:EHB04904.1, ECO:0000313|Proteomes:UP000006813};
RN [1] {ECO:0000313|EMBL:EHB04904.1, ECO:0000313|Proteomes:UP000006813}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21993625; DOI=10.1038/nature10533;
RA Kim E.B., Fang X., Fushan A.A., Huang Z., Lobanov A.V., Han L.,
RA Marino S.M., Sun X., Turanov A.A., Yang P., Yim S.H., Zhao X.,
RA Kasaikina M.V., Stoletzki N., Peng C., Polak P., Xiong Z., Kiezun A.,
RA Zhu Y., Chen Y., Kryukov G.V., Zhang Q., Peshkin L., Yang L., Bronson R.T.,
RA Buffenstein R., Wang B., Han C., Li Q., Chen L., Zhao W., Sunyaev S.R.,
RA Park T.J., Zhang G., Wang J., Gladyshev V.N.;
RT "Genome sequencing reveals insights into physiology and longevity of the
RT naked mole rat.";
RL Nature 479:223-227(2011).
RN [2] {ECO:0000313|EMBL:JAN99972.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Kidney {ECO:0000313|EMBL:JAN99972.1};
RA Bens M., Sahm A., Jahn N., Morhart M., Holtze S., Hildebrandt T.B.,
RA Platzer M., Szafranski K.;
RT "FRAMA: From RNA-seq data to annotated mRNA assemblies.";
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; JH168664; EHB04904.1; -; Genomic_DNA.
DR EMBL; GEBF01003660; JAN99972.1; -; Transcribed_RNA.
DR RefSeq; XP_004852491.1; XM_004852434.2.
DR AlphaFoldDB; G5B6M7; -.
DR STRING; 10181.G5B6M7; -.
DR GeneID; 101702424; -.
DR KEGG; hgl:101702424; -.
DR CTD; 29907; -.
DR eggNOG; KOG0603; Eukaryota.
DR eggNOG; KOG2101; Eukaryota.
DR InParanoid; G5B6M7; -.
DR OrthoDB; 5476410at2759; -.
DR Proteomes; UP000006813; Unassembled WGS sequence.
DR GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR CDD; cd02677; MIT_SNX15; 1.
DR Gene3D; 1.20.58.80; Phosphotransferase system, lactose/cellobiose-type IIA subunit; 1.
DR Gene3D; 3.30.1520.10; Phox-like domain; 1.
DR InterPro; IPR007330; MIT_dom.
DR InterPro; IPR036181; MIT_dom_sf.
DR InterPro; IPR001683; PX_dom.
DR InterPro; IPR036871; PX_dom_sf.
DR PANTHER; PTHR15508:SF8; LD24550P; 1.
DR PANTHER; PTHR15508; RIBOSOMAL PROTEIN S6 KINASE; 1.
DR Pfam; PF04212; MIT; 1.
DR Pfam; PF00787; PX; 1.
DR SMART; SM00745; MIT; 1.
DR SMART; SM00312; PX; 1.
DR SUPFAM; SSF116846; MIT domain; 1.
DR SUPFAM; SSF64268; PX domain; 1.
DR PROSITE; PS50195; PX; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000006813}.
FT DOMAIN 1..130
FT /note="PX"
FT /evidence="ECO:0000259|PROSITE:PS50195"
FT REGION 139..161
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 219..266
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 142..157
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 236..250
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 342 AA; 38395 MW; 1A82F232551A565E CRC64;
MSRQAKDDFL RHYTVCDPRT HPKGYTEYKV TAQFISKKDP EDIKEVVVWK RYSDFRKLHG
DLAYTHRNLF RRLEEFPAFP RGQVFGRFEA SVIEERRKAA EDLLRFTVHI PALNNSPQLK
EFFRGGEVIR PPEVSKDLHI LPPPLIPTPP PDDPRLPQPL PAERRGLEEL EVPVDPTPSS
PAQEALDLLF SCGSVEEASG SPARGPLSEA ELALFDPFSK EEGLGPSPTH VGELAATEVE
SKRLDQEPWE PGGQEEEEDE ERGPTPAYLS QATELITQAL RDEKAGAYPA ALQAYRDGVH
ILLRGVSSDP SPARREGVKK KAAEYLKRAE EILHLHVSQL PP
//
