ID G5B8G3_HETGA Unreviewed; 262 AA.
AC G5B8G3;
DT 14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2011, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Tropomyosin alpha-4 chain {ECO:0000313|EMBL:EHB05574.1};
GN ORFNames=GW7_13366 {ECO:0000313|EMBL:EHB05574.1};
OS Heterocephalus glaber (Naked mole rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae;
OC Heterocephalus.
OX NCBI_TaxID=10181 {ECO:0000313|EMBL:EHB05574.1, ECO:0000313|Proteomes:UP000006813};
RN [1] {ECO:0000313|EMBL:EHB05574.1, ECO:0000313|Proteomes:UP000006813}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21993625; DOI=10.1038/nature10533;
RA Kim E.B., Fang X., Fushan A.A., Huang Z., Lobanov A.V., Han L.,
RA Marino S.M., Sun X., Turanov A.A., Yang P., Yim S.H., Zhao X.,
RA Kasaikina M.V., Stoletzki N., Peng C., Polak P., Xiong Z., Kiezun A.,
RA Zhu Y., Chen Y., Kryukov G.V., Zhang Q., Peshkin L., Yang L., Bronson R.T.,
RA Buffenstein R., Wang B., Han C., Li Q., Chen L., Zhao W., Sunyaev S.R.,
RA Park T.J., Zhang G., Wang J., Gladyshev V.N.;
RT "Genome sequencing reveals insights into physiology and longevity of the
RT naked mole rat.";
RL Nature 479:223-227(2011).
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton
CC {ECO:0000256|ARBA:ARBA00004245}.
CC -!- SIMILARITY: Belongs to the tropomyosin family.
CC {ECO:0000256|ARBA:ARBA00009036}.
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DR EMBL; JH169001; EHB05574.1; -; Genomic_DNA.
DR AlphaFoldDB; G5B8G3; -.
DR STRING; 10181.G5B8G3; -.
DR eggNOG; KOG1003; Eukaryota.
DR InParanoid; G5B8G3; -.
DR Proteomes; UP000006813; Unassembled WGS sequence.
DR GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR Gene3D; 1.20.5.170; -; 1.
DR Gene3D; 1.20.5.340; -; 1.
DR InterPro; IPR000533; Tropomyosin.
DR PANTHER; PTHR19269; TROPOMYOSIN; 1.
DR PANTHER; PTHR19269:SF70; TROPOMYOSIN ALPHA-4 CHAIN; 1.
DR Pfam; PF00261; Tropomyosin; 1.
DR PRINTS; PR00194; TROPOMYOSIN.
DR SUPFAM; SSF57997; Tropomyosin; 1.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Muscle protein {ECO:0000256|ARBA:ARBA00023179};
KW Reference proteome {ECO:0000313|Proteomes:UP000006813}.
FT COILED 43..261
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 262 AA; 30223 MW; 26EA818E79FFD9C7 CRC64;
MRNVIVLYTY NVPIKEFNTK KKKKNLAAIA ELQTESPRAL AGLNSLDAVK RKIQALQQQA
EDEEDCAQRL QCELDGERER HEKAEGDVAA LNRHIQLVED LDQAQERLAT ALQKLEEAEK
AADESERGMK VIENWAMKDE EKMEIQELQL KEAKHIAEEA DRKYEEVARK LVILEGELER
AEERAEVSKL KCRDLDEELK NVTNNLKLLE AASEKYSEKE DKYEEEIKLL SDKLKEAETR
GEFAERTVAK LEKTIDDLED AK
//
