ID G5B8L0_HETGA Unreviewed; 487 AA.
AC G5B8L0;
DT 14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2011, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=Tudor and KH domain-containing protein {ECO:0000313|EMBL:EHB05621.1};
GN ORFNames=GW7_10304 {ECO:0000313|EMBL:EHB05621.1};
OS Heterocephalus glaber (Naked mole rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae;
OC Heterocephalus.
OX NCBI_TaxID=10181 {ECO:0000313|EMBL:EHB05621.1, ECO:0000313|Proteomes:UP000006813};
RN [1] {ECO:0000313|EMBL:EHB05621.1, ECO:0000313|Proteomes:UP000006813}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21993625; DOI=10.1038/nature10533;
RA Kim E.B., Fang X., Fushan A.A., Huang Z., Lobanov A.V., Han L.,
RA Marino S.M., Sun X., Turanov A.A., Yang P., Yim S.H., Zhao X.,
RA Kasaikina M.V., Stoletzki N., Peng C., Polak P., Xiong Z., Kiezun A.,
RA Zhu Y., Chen Y., Kryukov G.V., Zhang Q., Peshkin L., Yang L., Bronson R.T.,
RA Buffenstein R., Wang B., Han C., Li Q., Chen L., Zhao W., Sunyaev S.R.,
RA Park T.J., Zhang G., Wang J., Gladyshev V.N.;
RT "Genome sequencing reveals insights into physiology and longevity of the
RT naked mole rat.";
RL Nature 479:223-227(2011).
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DR EMBL; JH169004; EHB05621.1; -; Genomic_DNA.
DR AlphaFoldDB; G5B8L0; -.
DR STRING; 10181.G5B8L0; -.
DR eggNOG; KOG2279; Eukaryota.
DR InParanoid; G5B8L0; -.
DR Proteomes; UP000006813; Unassembled WGS sequence.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR CDD; cd20412; Tudor_TDRD2; 1.
DR Gene3D; 2.30.30.140; -; 1.
DR Gene3D; 2.40.50.90; -; 1.
DR Gene3D; 3.30.1370.10; K Homology domain, type 1; 1.
DR InterPro; IPR004087; KH_dom.
DR InterPro; IPR004088; KH_dom_type_1.
DR InterPro; IPR036612; KH_dom_type_1_sf.
DR InterPro; IPR035437; SNase_OB-fold_sf.
DR InterPro; IPR047380; TDRD2-like_tudor.
DR InterPro; IPR002999; Tudor.
DR PANTHER; PTHR22948:SF18; TUDOR AND KH DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR22948; TUDOR DOMAIN CONTAINING PROTEIN; 1.
DR Pfam; PF00013; KH_1; 1.
DR Pfam; PF00567; TUDOR; 1.
DR SMART; SM00322; KH; 1.
DR SMART; SM00333; TUDOR; 1.
DR SUPFAM; SSF54791; Eukaryotic type KH-domain (KH-domain type I); 1.
DR SUPFAM; SSF63748; Tudor/PWWP/MBT; 1.
DR PROSITE; PS50084; KH_TYPE_1; 1.
DR PROSITE; PS50304; TUDOR; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000006813};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00117}.
FT DOMAIN 279..338
FT /note="Tudor"
FT /evidence="ECO:0000259|PROSITE:PS50304"
FT REGION 139..170
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 139..154
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 487 AA; 53899 MW; D6BFF7545A875FA6 CRC64;
MEKDVRGQWK MSTEQTSWTS LSTLQKVALG LGIPASAAVA YILYRRYRES REERLTFVGD
NDIEIEMRVP QEAVKLIIGR QGANIKQTGA RIDVDTEDVG EECVLLISGF PVQHLILEKV
SEDEELRKRI AHSAEARVPR KQPISVRREE TESGGAGEPA LWENASSGSG GRQAAALAVP
ARKGGGDPTV VRPKEGSWEE ADHGFQESGA QASPEKSIFE IPSPDFSFHA DEYLEVYVSA
SEHPNHFWIQ IVGSRSLQLD KLVSEMTQHY ENSPPEDLTA RVGDIVAAPL SANGSWYRAR
ILGTLENGNL DLYFVDFGDN GDCPLRDLRA LRSDFLSLPF QAIECSLARI APSGEQWEEE
ALDEFDRLTY CADWKPLVAK ISSYVQTGIS TWPKIYLYDT SNGKKLDIGL ELVRKGYAIE
LPEDVEENRA VPDMLKDMAT ETDASLASML TEPRKSPGEL AHTLSCLSLS EAASMSGDDN
LEDDYLL
//
