ID G5BCV9_HETGA Unreviewed; 341 AA.
AC G5BCV9;
DT 14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2011, sequence version 1.
DT 24-JAN-2024, entry version 32.
DE SubName: Full=Inositol polyphosphate 5-phosphatase K {ECO:0000313|EMBL:EHB07120.1};
DE Flags: Fragment;
GN ORFNames=GW7_05098 {ECO:0000313|EMBL:EHB07120.1};
OS Heterocephalus glaber (Naked mole rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae;
OC Heterocephalus.
OX NCBI_TaxID=10181 {ECO:0000313|EMBL:EHB07120.1, ECO:0000313|Proteomes:UP000006813};
RN [1] {ECO:0000313|EMBL:EHB07120.1, ECO:0000313|Proteomes:UP000006813}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21993625; DOI=10.1038/nature10533;
RA Kim E.B., Fang X., Fushan A.A., Huang Z., Lobanov A.V., Han L.,
RA Marino S.M., Sun X., Turanov A.A., Yang P., Yim S.H., Zhao X.,
RA Kasaikina M.V., Stoletzki N., Peng C., Polak P., Xiong Z., Kiezun A.,
RA Zhu Y., Chen Y., Kryukov G.V., Zhang Q., Peshkin L., Yang L., Bronson R.T.,
RA Buffenstein R., Wang B., Han C., Li Q., Chen L., Zhao W., Sunyaev S.R.,
RA Park T.J., Zhang G., Wang J., Gladyshev V.N.;
RT "Genome sequencing reveals insights into physiology and longevity of the
RT naked mole rat.";
RL Nature 479:223-227(2011).
CC -!- SIMILARITY: Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase
CC type II family. {ECO:0000256|ARBA:ARBA00005910}.
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DR EMBL; JH169574; EHB07120.1; -; Genomic_DNA.
DR AlphaFoldDB; G5BCV9; -.
DR STRING; 10181.G5BCV9; -.
DR eggNOG; KOG0565; Eukaryota.
DR InParanoid; G5BCV9; -.
DR Proteomes; UP000006813; Unassembled WGS sequence.
DR GO; GO:0016791; F:phosphatase activity; IEA:InterPro.
DR GO; GO:0046856; P:phosphatidylinositol dephosphorylation; IEA:InterPro.
DR Gene3D; 2.60.40.2840; -; 1.
DR Gene3D; 3.60.10.10; Endonuclease/exonuclease/phosphatase; 2.
DR InterPro; IPR036691; Endo/exonu/phosph_ase_sf.
DR InterPro; IPR046985; IP5.
DR InterPro; IPR000300; IPPc.
DR InterPro; IPR041611; SKICH.
DR PANTHER; PTHR11200; INOSITOL 5-PHOSPHATASE; 1.
DR PANTHER; PTHR11200:SF117; INOSITOL POLYPHOSPHATE 5-PHOSPHATASE K; 1.
DR Pfam; PF17751; SKICH; 1.
DR SMART; SM00128; IPPc; 1.
DR SUPFAM; SSF56219; DNase I-like; 2.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000006813}.
FT DOMAIN 1..216
FT /note="Inositol polyphosphate-related phosphatase"
FT /evidence="ECO:0000259|SMART:SM00128"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EHB07120.1"
SQ SEQUENCE 341 AA; 38887 MW; E42235AA87D299A7 CRC64;
SIHVVTWNVA SEVPPLDLSD LLQLNDPNLN LDICIIGLQE VNSGIISLLS NTAFEDPWSS
FFMDVLSPLS FVKISHVRMQ GLLLMVFVKY QHLPFIQILS TKSTPTGLYG YWLTIAKTHD
PLLREFLEGP LHFPPTYKFD KNSNNYDTSE KKRKPAWTDR ILWRLKRQLQ ARSFTPSLPA
PSFTLSLKSY KSHMMYSISD HKPVTGTFDL ELKPLLSVPL ITMMAEGLWT MENEMLISYS
STPDFLSSPW DWIGLYKVGM RHINDYVSYV WVGDNQVSFG DNLKQVYMNI CDIPENEDQY
LLCYYSNNLH SVVGISKPFK VRDAGGRGYY GSEATGSEAN P
//
