ID G5BK60_HETGA Unreviewed; 1061 AA.
AC G5BK60;
DT 14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2011, sequence version 1.
DT 24-JAN-2024, entry version 29.
DE SubName: Full=Protein AF-17 {ECO:0000313|EMBL:EHB09671.1};
DE Flags: Fragment;
GN ORFNames=GW7_13062 {ECO:0000313|EMBL:EHB09671.1};
OS Heterocephalus glaber (Naked mole rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae;
OC Heterocephalus.
OX NCBI_TaxID=10181 {ECO:0000313|EMBL:EHB09671.1, ECO:0000313|Proteomes:UP000006813};
RN [1] {ECO:0000313|EMBL:EHB09671.1, ECO:0000313|Proteomes:UP000006813}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21993625; DOI=10.1038/nature10533;
RA Kim E.B., Fang X., Fushan A.A., Huang Z., Lobanov A.V., Han L.,
RA Marino S.M., Sun X., Turanov A.A., Yang P., Yim S.H., Zhao X.,
RA Kasaikina M.V., Stoletzki N., Peng C., Polak P., Xiong Z., Kiezun A.,
RA Zhu Y., Chen Y., Kryukov G.V., Zhang Q., Peshkin L., Yang L., Bronson R.T.,
RA Buffenstein R., Wang B., Han C., Li Q., Chen L., Zhao W., Sunyaev S.R.,
RA Park T.J., Zhang G., Wang J., Gladyshev V.N.;
RT "Genome sequencing reveals insights into physiology and longevity of the
RT naked mole rat.";
RL Nature 479:223-227(2011).
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DR EMBL; JH170690; EHB09671.1; -; Genomic_DNA.
DR AlphaFoldDB; G5BK60; -.
DR STRING; 10181.G5BK60; -.
DR eggNOG; KOG0956; Eukaryota.
DR InParanoid; G5BK60; -.
DR Proteomes; UP000006813; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd15709; ePHD_AF17; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR034732; EPHD.
DR InterPro; IPR001965; Znf_PHD.
DR InterPro; IPR019787; Znf_PHD-finger.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR13793; PHD FINGER PROTEINS; 1.
DR PANTHER; PTHR13793:SF90; PROTEIN AF-17; 1.
DR Pfam; PF13832; zf-HC5HC2H_2; 1.
DR SMART; SM00249; PHD; 1.
DR PROSITE; PS51805; EPHD; 1.
DR PROSITE; PS50016; ZF_PHD_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000006813};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00146}.
FT DOMAIN 26..145
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS51805"
FT DOMAIN 81..144
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS50016"
FT REGION 152..376
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 389..470
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 756..817
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1028..1061
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 696..730
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 206..220
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 251..266
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 267..282
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 288..335
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 406..420
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 761..812
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EHB09671.1"
SQ SEQUENCE 1061 AA; 107580 MW; 57E0CDB5DBCAAC30 CRC64;
ACYGIVQVPT GPWFCRKCES QERAARVRCE LCPHKDGALK RTDNGGWAHV VCALYIPEVQ
FANVLTMEPI VLQYVPHDRF SKTCYICEEQ GRESKAASGA CMTCNRHGCR QAFHVTCAQM
AGLLCEEEVL EVDNVKYCGY CKYHFSKMKT SRHGGGGGAG TGGAGSGGGS GGGNGGGGSG
AGTGGGGSGF VAGRRSRSAS PSTQQEKHAA HHERGQKKSR KDKERLKQKH KKRPESPAST
LTPPVGPAAD KVSSSASSSS HHEASTQETS ESSRDSKGKK SSSHGLSHKG KKLSSSGKGV
SSFTSTSSSS SSSSSGGPFQ PAGSSLQSSP DFSAFPKLEQ SEEDKYSKPV APTASAPSSP
SAPEPPKTDL FDQKGVFSGF GPIMRFTAAS SSGRARAPSP GDYKSPHISG SGTSAGTHKR
MPALSATPVP TEGSLEPGLK EKKHKASKRS RHGPGRPKGS RNKEGVGPPA VPTLPAAQLA
GFTATAASPF SGGSLVSSGL GGLASHTFGP SGSLPSLSLE SPLLGAGIYT SNKDPISHGG
SMLRAVCSTP LSSSLLGPPG TSALPRLSRS PFTSTLPSSS SASISTTQVF PLAGSTFSLP
STHIFGTSVG TTNPLLTQAE SSHAEPDLED CSFRCRGTSP QESAGSAVGS GHDPALALGW
VICGPAPPQP GFPACQPPPP PPHPRAQTTL APVSAVVEML KALHALQKEN QRLQEQILSL
TAKKERLELL NVQLSVPFPS LPAVLPAANG PIPGPYGLLP QASSDSLSTS KSPPGKNSLG
LDNSLSTSSE DPHSGCPSRS SSSLSFHSTP PPLPLLQQSP AALPLALPGA PAPLPAQPQN
GLGRAPGAAG LGAMPVAEGL LGGLSGGGGL PLNGLLGGLN GAAAPNPAAL SQAGGPPALQ
LPGCLNSLTE QQRHLLQQQD QQLQQLQQLL ASPQLTPEHQ AVVYQMIQQV QQKRELQRLQ
MAGGSQLPMA GLLAGSSTPL LSAASAPALL PTGALVAPSL GSNTSLMAAA AAAAAVAAAG
GPPVLTAQTN PFLSLSGADS SGSGPKGGAA DKGASANQEK G
//
