ID   G5BMH0_HETGA            Unreviewed;       828 AA.
AC   G5BMH0;
DT   14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT   14-DEC-2011, sequence version 1.
DT   24-JAN-2024, entry version 43.
DE   SubName: Full=Sarcolemmal membrane-associated protein {ECO:0000313|EMBL:EHB10481.1};
GN   ORFNames=GW7_03971 {ECO:0000313|EMBL:EHB10481.1};
OS   Heterocephalus glaber (Naked mole rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae;
OC   Heterocephalus.
OX   NCBI_TaxID=10181 {ECO:0000313|EMBL:EHB10481.1, ECO:0000313|Proteomes:UP000006813};
RN   [1] {ECO:0000313|EMBL:EHB10481.1, ECO:0000313|Proteomes:UP000006813}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=21993625; DOI=10.1038/nature10533;
RA   Kim E.B., Fang X., Fushan A.A., Huang Z., Lobanov A.V., Han L.,
RA   Marino S.M., Sun X., Turanov A.A., Yang P., Yim S.H., Zhao X.,
RA   Kasaikina M.V., Stoletzki N., Peng C., Polak P., Xiong Z., Kiezun A.,
RA   Zhu Y., Chen Y., Kryukov G.V., Zhang Q., Peshkin L., Yang L., Bronson R.T.,
RA   Buffenstein R., Wang B., Han C., Li Q., Chen L., Zhao W., Sunyaev S.R.,
RA   Park T.J., Zhang G., Wang J., Gladyshev V.N.;
RT   "Genome sequencing reveals insights into physiology and longevity of the
RT   naked mole rat.";
RL   Nature 479:223-227(2011).
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DR   EMBL; JH171019; EHB10481.1; -; Genomic_DNA.
DR   AlphaFoldDB; G5BMH0; -.
DR   STRING; 10181.G5BMH0; -.
DR   Ensembl; ENSHGLT00100072028; ENSHGLP00100058074; ENSHGLG00100010186.
DR   eggNOG; KOG3872; Eukaryota.
DR   InParanoid; G5BMH0; -.
DR   Proteomes; UP000006813; Unassembled WGS sequence.
DR   Bgee; ENSHGLG00000004066; Expressed in heart and 10 other cell types or tissues.
DR   GO; GO:0005615; C:extracellular space; IEA:InterPro.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   CDD; cd21911; CC1_SLMAP; 1.
DR   CDD; cd22679; FHA_SLMAP; 1.
DR   Gene3D; 2.60.200.20; -; 1.
DR   InterPro; IPR000253; FHA_dom.
DR   InterPro; IPR001363; Prot_inh_fetuin_CS.
DR   InterPro; IPR008984; SMAD_FHA_dom_sf.
DR   PANTHER; PTHR15715; CENTROSOMAL PROTEIN OF 170 KDA; 1.
DR   PANTHER; PTHR15715:SF22; SARCOLEMMAL MEMBRANE-ASSOCIATED PROTEIN; 1.
DR   Pfam; PF00498; FHA; 1.
DR   SMART; SM00240; FHA; 1.
DR   SUPFAM; SSF49879; SMAD/FHA domain; 1.
DR   PROSITE; PS01255; FETUIN_2; 1.
DR   PROSITE; PS50006; FHA_DOMAIN; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000006813};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        801..820
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          28..85
FT                   /note="FHA"
FT                   /evidence="ECO:0000259|PROSITE:PS50006"
FT   REGION          436..467
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          172..199
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          233..387
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          492..565
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          595..795
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        436..464
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   828 AA;  95033 MW;  5651F7F4FB2DE69E CRC64;
     MPSALAIFTC RPNSHPFQER HVYLDEPIKI GRSVARCRPA QNNATFDCKV LSRNHALVWF
     DHKTGKFYLQ DTKSSNGTFI NSQRLSRGSE ESPPCEILSG DIIQFGVDVT ENTRKVTHGC
     IVSTIKLFLP DGMEARLRSD VIHAPLPSPV DKVAANTPSM YSQELFQLSQ YLQEALHREQ
     MLEQKLATLQ RLLAITQEAS DTSWQALIDE DRLLSRLEVM GNQLQACSKN QTEDSLRKEL
     IALQEDKHNY ETTAKESLRR VLQEKIEVVR KLSEVERSLS NTEDECTHLK EMNERTQEEL
     RELANKYNGA VNEIKDLSDK LKVAEGKQEE IQQKGQAEKK ELQHKIDEME EKEQELQAKI
     EALQADNDFT NERLTALQVR LEHLQEKTLK ECSSLEHLLS KSGGDCTFIH QFIECQKKLI
     VEGHLTKVVE ETKLSKENQA RAKESDLSDT LSPSKEKSSD DTTDAQMDEQ DLNEPLAKVS
     LLKDDSQGAQ SEIEAKQEIQ HLRKELIEAQ ELARTSKQKC FELQALLEEE RKAYRNQVEE
     SAKQIQVLQA QLQRLHIDIE NLREEKDSEV TSTRDELLSA RDEILLLHQA AAKAASERDT
     DIASLQEELK KVRAELDRWR KAASEYEREI TGLQNSFQLR CQQCEDQQRE EATRLQGELE
     KLKKEWNVLE TECHSLKKEN VLLSSELQRQ EKELHNSQKQ SLELTSDLSI LQMTRKELEN
     QVGSLKEQHL RDSADLKTLL TKAESQAKDV QKEYEKTQTV LSELKLKFEM TEQEKQSITD
     QLKQCKDNLK LLREKGNNKP WPWMPMLAAL VAVTAIVLYV PGLARASP
//