ID G5BRT1_HETGA Unreviewed; 394 AA.
AC G5BRT1;
DT 14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2011, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE SubName: Full=DDI1-like protein 2 {ECO:0000313|EMBL:EHB11993.1};
DE Flags: Fragment;
GN ORFNames=GW7_15513 {ECO:0000313|EMBL:EHB11993.1};
OS Heterocephalus glaber (Naked mole rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae;
OC Heterocephalus.
OX NCBI_TaxID=10181 {ECO:0000313|EMBL:EHB11993.1, ECO:0000313|Proteomes:UP000006813};
RN [1] {ECO:0000313|EMBL:EHB11993.1, ECO:0000313|Proteomes:UP000006813}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21993625; DOI=10.1038/nature10533;
RA Kim E.B., Fang X., Fushan A.A., Huang Z., Lobanov A.V., Han L.,
RA Marino S.M., Sun X., Turanov A.A., Yang P., Yim S.H., Zhao X.,
RA Kasaikina M.V., Stoletzki N., Peng C., Polak P., Xiong Z., Kiezun A.,
RA Zhu Y., Chen Y., Kryukov G.V., Zhang Q., Peshkin L., Yang L., Bronson R.T.,
RA Buffenstein R., Wang B., Han C., Li Q., Chen L., Zhao W., Sunyaev S.R.,
RA Park T.J., Zhang G., Wang J., Gladyshev V.N.;
RT "Genome sequencing reveals insights into physiology and longevity of the
RT naked mole rat.";
RL Nature 479:223-227(2011).
CC -!- SIMILARITY: Belongs to the DDI1 family.
CC {ECO:0000256|ARBA:ARBA00009136}.
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DR EMBL; JH171561; EHB11993.1; -; Genomic_DNA.
DR AlphaFoldDB; G5BRT1; -.
DR STRING; 10181.G5BRT1; -.
DR eggNOG; KOG0012; Eukaryota.
DR InParanoid; G5BRT1; -.
DR Proteomes; UP000006813; Unassembled WGS sequence.
DR GO; GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR CDD; cd05479; RP_DDI; 1.
DR CDD; cd01796; Ubl_Ddi1_like; 1.
DR Gene3D; 2.40.70.10; Acid Proteases; 1.
DR InterPro; IPR033882; DDI1_N.
DR InterPro; IPR019103; Peptidase_aspartic_DDI1-type.
DR InterPro; IPR021109; Peptidase_aspartic_dom_sf.
DR InterPro; IPR000626; Ubiquitin-like_dom.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR PANTHER; PTHR15397:SF3; DNA DAMAGE-INDUCIBLE 1 HOMOLOG 2; 1.
DR PANTHER; PTHR15397; SODIUM-GLUCOSE COTRANSPORTER REGULATORY PROTEIN -RELATED; 1.
DR Pfam; PF09668; Asp_protease; 1.
DR Pfam; PF00240; ubiquitin; 1.
DR SUPFAM; SSF50630; Acid proteases; 1.
DR SUPFAM; SSF54236; Ubiquitin-like; 1.
DR PROSITE; PS50053; UBIQUITIN_2; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000006813}.
FT DOMAIN 1..81
FT /note="Ubiquitin-like"
FT /evidence="ECO:0000259|PROSITE:PS50053"
FT REGION 103..132
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 103..128
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 394
FT /evidence="ECO:0000313|EMBL:EHB11993.1"
SQ SEQUENCE 394 AA; 43765 MW; 8D018F4D23FBCD63 CRC64;
MLLTVYCVRR DLSEVTFSLQ VDADFELHNF RALCELESGI PAAESQLVYA ERPLTDNHRS
LASYGLKDGD VVILRQKENA DPRPAVQFPN LPRIDFSSIA VPGTSSPCQR QAAGAQQPHS
SPGEIASSPQ GLDNPALLRD MLLANPHELS LLKERNPPLA EALLSGDLER FSRVLVEQQQ
DRARREQERI RLFSADPFDL EAQAKIEEDI RQQNIEENMT IAMEEAPESF GQVVMLYINC
KVNGHPVKAF VDSGAQMTIM SQSCAERCNI MRLVDRRWAG IAKGVGTQKI IGRVHLAQVQ
IEGDFLACSF SILEEQPMDM LLGLDMLKRH QCSIDLKKNV LVIGTTGSQT TFLPEGELPE
CARLAYGTGR EDIRPEEIAD QELAEAIQKS AEDA
//
