ID G5BSW4_HETGA Unreviewed; 318 AA.
AC G5BSW4;
DT 14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2011, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE RecName: Full=Olfactory receptor {ECO:0000256|RuleBase:RU363047};
GN ORFNames=GW7_04878 {ECO:0000313|EMBL:EHB12380.1};
OS Heterocephalus glaber (Naked mole rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae;
OC Heterocephalus.
OX NCBI_TaxID=10181 {ECO:0000313|EMBL:EHB12380.1, ECO:0000313|Proteomes:UP000006813};
RN [1] {ECO:0000313|EMBL:EHB12380.1, ECO:0000313|Proteomes:UP000006813}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21993625; DOI=10.1038/nature10533;
RA Kim E.B., Fang X., Fushan A.A., Huang Z., Lobanov A.V., Han L.,
RA Marino S.M., Sun X., Turanov A.A., Yang P., Yim S.H., Zhao X.,
RA Kasaikina M.V., Stoletzki N., Peng C., Polak P., Xiong Z., Kiezun A.,
RA Zhu Y., Chen Y., Kryukov G.V., Zhang Q., Peshkin L., Yang L., Bronson R.T.,
RA Buffenstein R., Wang B., Han C., Li Q., Chen L., Zhao W., Sunyaev S.R.,
RA Park T.J., Zhang G., Wang J., Gladyshev V.N.;
RT "Genome sequencing reveals insights into physiology and longevity of the
RT naked mole rat.";
RL Nature 479:223-227(2011).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU363047};
CC Multi-pass membrane protein {ECO:0000256|RuleBase:RU363047}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family.
CC {ECO:0000256|RuleBase:RU000688}.
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DR EMBL; JH171655; EHB12380.1; -; Genomic_DNA.
DR RefSeq; XP_012932922.1; XM_013077468.1.
DR AlphaFoldDB; G5BSW4; -.
DR STRING; 10181.G5BSW4; -.
DR Ensembl; ENSHGLT00000017665; ENSHGLP00000049931; ENSHGLG00000012524.
DR Ensembl; ENSHGLT00100006596; ENSHGLP00100047960; ENSHGLG00100004879.
DR GeneID; 101705084; -.
DR KEGG; hgl:101705084; -.
DR InParanoid; G5BSW4; -.
DR OrthoDB; 5309199at2759; -.
DR Proteomes; UP000006813; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW.
DR GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
DR CDD; cd15224; 7tmA_OR6B-like; 1.
DR Gene3D; 1.20.1070.10; Rhodopsin 7-helix transmembrane proteins; 1.
DR InterPro; IPR000276; GPCR_Rhodpsn.
DR InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR InterPro; IPR000725; Olfact_rcpt.
DR PANTHER; PTHR26452; OLFACTORY RECEPTOR; 1.
DR PANTHER; PTHR26452:SF99; OLFACTORY RECEPTOR; 1.
DR Pfam; PF13853; 7tm_4; 1.
DR PRINTS; PR00237; GPCRRHODOPSN.
DR PRINTS; PR00245; OLFACTORYR.
DR SUPFAM; SSF81321; Family A G protein-coupled receptor-like; 1.
DR PROSITE; PS00237; G_PROTEIN_RECEP_F1_1; 1.
DR PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW ECO:0000256|RuleBase:RU363047};
KW G-protein coupled receptor {ECO:0000256|ARBA:ARBA00023040,
KW ECO:0000256|RuleBase:RU000688};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU363047};
KW Olfaction {ECO:0000256|RuleBase:RU363047};
KW Receptor {ECO:0000256|ARBA:ARBA00023170, ECO:0000256|RuleBase:RU000688};
KW Reference proteome {ECO:0000313|Proteomes:UP000006813};
KW Sensory transduction {ECO:0000256|RuleBase:RU363047};
KW Transducer {ECO:0000256|ARBA:ARBA00023224, ECO:0000256|RuleBase:RU000688};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU000688};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU363047}.
FT TRANSMEM 27..53
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363047"
FT TRANSMEM 65..87
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363047"
FT TRANSMEM 107..125
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363047"
FT TRANSMEM 145..169
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363047"
FT TRANSMEM 205..230
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363047"
FT TRANSMEM 242..265
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363047"
FT TRANSMEM 277..297
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363047"
FT DOMAIN 46..295
FT /note="G-protein coupled receptors family 1 profile"
FT /evidence="ECO:0000259|PROSITE:PS50262"
SQ SEQUENCE 318 AA; 35920 MW; 14B59610EDED408C CRC64;
MTTMGLEVGN HTETAYFVLL GFPTLPAFQL LLFSIFLATY LLTLLENLLI ILAIRSDGQL
HKPMYFFLSH LSFLEMWYVT AICPKMLVDF LSSDKSISFN GCMTQLYFFV TFVCTEYILL
AIMAFDRYVA ICNPLRYPVI MTNQLCGTLA GGCWSCGLMT AMIKIVYIAR LHYCGTPHIN
HYFCDISPLL NVSCEDSSQA ELVDFFLALM VIAVPLCVVV ASYATILITI LKIPSAQGRQ
KAFSTCASHL TVVILFYSTT LFTYARPKLM YAYNSNKVVS VLYTVIVPLL NPIIYCLRNR
EVKEALKKTM FCNRSVPH
//
