ID G5BTQ0_HETGA Unreviewed; 383 AA.
AC G5BTQ0;
DT 14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2011, sequence version 1.
DT 24-JAN-2024, entry version 19.
DE SubName: Full=DENN domain-containing protein 2C {ECO:0000313|EMBL:EHB12661.1};
DE Flags: Fragment;
GN ORFNames=GW7_18565 {ECO:0000313|EMBL:EHB12661.1};
OS Heterocephalus glaber (Naked mole rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae;
OC Heterocephalus.
OX NCBI_TaxID=10181 {ECO:0000313|EMBL:EHB12661.1, ECO:0000313|Proteomes:UP000006813};
RN [1] {ECO:0000313|EMBL:EHB12661.1, ECO:0000313|Proteomes:UP000006813}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21993625; DOI=10.1038/nature10533;
RA Kim E.B., Fang X., Fushan A.A., Huang Z., Lobanov A.V., Han L.,
RA Marino S.M., Sun X., Turanov A.A., Yang P., Yim S.H., Zhao X.,
RA Kasaikina M.V., Stoletzki N., Peng C., Polak P., Xiong Z., Kiezun A.,
RA Zhu Y., Chen Y., Kryukov G.V., Zhang Q., Peshkin L., Yang L., Bronson R.T.,
RA Buffenstein R., Wang B., Han C., Li Q., Chen L., Zhao W., Sunyaev S.R.,
RA Park T.J., Zhang G., Wang J., Gladyshev V.N.;
RT "Genome sequencing reveals insights into physiology and longevity of the
RT naked mole rat.";
RL Nature 479:223-227(2011).
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DR EMBL; JH171761; EHB12661.1; -; Genomic_DNA.
DR AlphaFoldDB; G5BTQ0; -.
DR STRING; 10181.G5BTQ0; -.
DR eggNOG; KOG3569; Eukaryota.
DR InParanoid; G5BTQ0; -.
DR Proteomes; UP000006813; Unassembled WGS sequence.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
DR Gene3D; 3.30.450.200; -; 1.
DR Gene3D; 3.40.50.11500; -; 1.
DR InterPro; IPR001194; cDENN_dom.
DR InterPro; IPR005112; dDENN_dom.
DR InterPro; IPR043153; DENN_C.
DR InterPro; IPR037516; Tripartite_DENN.
DR InterPro; IPR005113; uDENN_dom.
DR PANTHER; PTHR15288; DENN DOMAIN-CONTAINING PROTEIN 2; 1.
DR PANTHER; PTHR15288:SF6; DENN DOMAIN-CONTAINING PROTEIN 2C; 1.
DR Pfam; PF03455; dDENN; 1.
DR Pfam; PF02141; DENN; 1.
DR Pfam; PF03456; uDENN; 1.
DR SMART; SM00801; dDENN; 1.
DR SMART; SM00799; DENN; 1.
DR SMART; SM00800; uDENN; 1.
DR PROSITE; PS50211; DENN; 1.
PE 4: Predicted;
KW Guanine-nucleotide releasing factor {ECO:0000256|ARBA:ARBA00022658};
KW Reference proteome {ECO:0000313|Proteomes:UP000006813}.
FT DOMAIN 1..363
FT /note="UDENN"
FT /evidence="ECO:0000259|PROSITE:PS50211"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EHB12661.1"
FT NON_TER 383
FT /evidence="ECO:0000313|EMBL:EHB12661.1"
SQ SEQUENCE 383 AA; 43827 MW; 17FE8B3CF9C8AD32 CRC64;
QSKDTEERLK VIPKFCFPDS EDWVPTSELK SETFSFVLTG EDGSRWFGYC KKLLPESKGK
QLPEVYCMVN RLGCFNLFSK ILDEVEKRRE MSPALVYPFM RSVMEAPFPA PGRNITVKSY
LPGAGDGSIE LCRPLDSRLE HVDFECLSKC LSVCHLIRVC ASLLLERRII FVANSLSTLS
KCGHAVVATL YPFTWQHTYI PVLPASMIDI MCSPTPFLIG ILPFSLPQLQ DLPIEEVPIV
DLCADKFLQE VSDENEILPP KFQAALIQIL EERNEILSQE KIFSQDVTLN SLVSEAFVRF
FVELVGHYSL NMTVTERGER IFQREPFRKS HTSRSVRHFL DLFMETQMFA GFIQDQELRK
SGIKGLFEVW ALQYLETIPE SEP
//
