GenomeNet

Database: UniProt
Entry: G5BUR9_HETGA
LinkDB: G5BUR9_HETGA
Original site: G5BUR9_HETGA 
ID   G5BUR9_HETGA            Unreviewed;      2892 AA.
AC   G5BUR9;
DT   14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT   14-DEC-2011, sequence version 1.
DT   12-AUG-2020, entry version 29.
DE   SubName: Full=Centromere protein F {ECO:0000313|EMBL:EHB13029.1};
GN   ORFNames=GW7_11981 {ECO:0000313|EMBL:EHB13029.1};
OS   Heterocephalus glaber (Naked mole rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae;
OC   Heterocephalus.
OX   NCBI_TaxID=10181 {ECO:0000313|EMBL:EHB13029.1, ECO:0000313|Proteomes:UP000006813};
RN   [1] {ECO:0000313|EMBL:EHB13029.1, ECO:0000313|Proteomes:UP000006813}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=21993625; DOI=10.1038/nature10533;
RA   Kim E.B., Fang X., Fushan A.A., Huang Z., Lobanov A.V., Han L.,
RA   Marino S.M., Sun X., Turanov A.A., Yang P., Yim S.H., Zhao X.,
RA   Kasaikina M.V., Stoletzki N., Peng C., Polak P., Xiong Z., Kiezun A.,
RA   Zhu Y., Chen Y., Kryukov G.V., Zhang Q., Peshkin L., Yang L., Bronson R.T.,
RA   Buffenstein R., Wang B., Han C., Li Q., Chen L., Zhao W., Sunyaev S.R.,
RA   Park T.J., Zhang G., Wang J., Gladyshev V.N.;
RT   "Genome sequencing reveals insights into physiology and longevity of the
RT   naked mole rat.";
RL   Nature 479:223-227(2011).
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; JH171970; EHB13029.1; -; Genomic_DNA.
DR   STRING; 10181.XP_004853623.1; -.
DR   eggNOG; ENOG502QVMD; Eukaryota.
DR   InParanoid; G5BUR9; -.
DR   OMA; YNAQLVQ; -.
DR   Proteomes; UP000006813; Unassembled WGS sequence.
DR   GO; GO:0005930; C:axoneme; IEA:Ensembl.
DR   GO; GO:0005813; C:centrosome; IEA:Ensembl.
DR   GO; GO:0036064; C:ciliary basal body; IEA:Ensembl.
DR   GO; GO:0097539; C:ciliary transition fiber; IEA:Ensembl.
DR   GO; GO:0000940; C:condensed chromosome outer kinetochore; IEA:Ensembl.
DR   GO; GO:0030496; C:midbody; IEA:Ensembl.
DR   GO; GO:0005635; C:nuclear envelope; IEA:Ensembl.
DR   GO; GO:0016363; C:nuclear matrix; IEA:Ensembl.
DR   GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR   GO; GO:0045120; C:pronucleus; IEA:Ensembl.
DR   GO; GO:0000922; C:spindle pole; IEA:Ensembl.
DR   GO; GO:0070840; F:dynein complex binding; IEA:Ensembl.
DR   GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR   GO; GO:0008022; F:protein C-terminus binding; IEA:Ensembl.
DR   GO; GO:0042803; F:protein homodimerization activity; IEA:Ensembl.
DR   GO; GO:0008134; F:transcription factor binding; IEA:Ensembl.
DR   GO; GO:0001822; P:kidney development; IEA:Ensembl.
DR   GO; GO:0051310; P:metaphase plate congression; IEA:Ensembl.
DR   GO; GO:0000278; P:mitotic cell cycle; IEA:Ensembl.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0015031; P:protein transport; IEA:Ensembl.
DR   GO; GO:0010389; P:regulation of G2/M transition of mitotic cell cycle; IEA:Ensembl.
DR   GO; GO:0016202; P:regulation of striated muscle tissue development; IEA:Ensembl.
DR   GO; GO:0021591; P:ventricular system development; IEA:Ensembl.
DR   InterPro; IPR043513; Cenp-F.
DR   InterPro; IPR018302; CenpF/LEK1_Rb-prot-bd.
DR   InterPro; IPR019513; Centromere_CenpF_leu-rich_rpt.
DR   InterPro; IPR018463; Centromere_CenpF_N.
DR   PANTHER; PTHR18874; PTHR18874; 2.
DR   Pfam; PF10490; CENP-F_C_Rb_bdg; 1.
DR   Pfam; PF10473; CENP-F_leu_zip; 2.
DR   Pfam; PF10481; CENP-F_N; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Reference proteome {ECO:0000313|Proteomes:UP000006813}.
FT   DOMAIN          1..234
FT                   /note="CENP-F_N"
FT                   /evidence="ECO:0000259|Pfam:PF10481"
FT   DOMAIN          2028..2167
FT                   /note="CENP-F_leu_zip"
FT                   /evidence="ECO:0000259|Pfam:PF10473"
FT   DOMAIN          2210..2349
FT                   /note="CENP-F_leu_zip"
FT                   /evidence="ECO:0000259|Pfam:PF10473"
FT   DOMAIN          2752..2795
FT                   /note="CENP-F_C_Rb_bdg"
FT                   /evidence="ECO:0000259|Pfam:PF10490"
FT   REGION          138..166
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          178..201
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          388..424
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          2176..2195
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          2668..2892
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          4..52
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          91..118
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          207..255
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          263..311
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          313..340
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          450..542
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          578..605
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          613..700
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          765..792
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          832..950
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          955..1010
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1051..1085
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1136..1170
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1219..1246
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1258..1278
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1316..1343
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1365..1385
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1462..1525
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1539..1559
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1703..1751
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1808..1835
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1885..1905
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1913..1982
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2011..2031
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2039..2122
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2126..2175
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2221..2241
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2249..2350
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2365..2392
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2400..2441
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2452..2500
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2515..2560
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2565..2609
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2619..2646
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        181..201
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        2668..2694
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        2702..2736
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        2738..2753
FT                   /note="Polyampholyte"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        2781..2795
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        2811..2854
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   2892 AA;  329377 MW;  9128E9A58010D1DB CRC64;
     MEICENLEKS KQKISHELQV KESQVNFQEG QLNSGRKQIE KLEQELKRCK SGLERSHPAA
     PPADCSLCAC SSLQIFAAPP TPGQPYSGSK YEDLREKYNK EVEERRRLEA EVKVLQAKRA
     SQAVPPTTMN HRDIARHQAS SSVFSWQQER TPNQLPSHPQ KTPSRRDFSA SHIFGEEEVT
     PSRSVLQTGK RDTNSSCHDN SCSSPLLDQL KGQNQELRSE VNELQLRLQG QEKEMESQAH
     RFQELQLQLE KTKVELIEKD KILKKNRDEL ARTTAQYEQA ATQCTALEQK LKKLTEDLNC
     QRQNAESARC ALEQRVKKKE KALQEELSRQ QRAFQTLDQE CMQMKARLTQ ELQQAKNALC
     GLEAELHKVT SVKQQLEKNL EELKQKFSRM EQASKDRQVE EEALRRSSQE TKKENGFLRT
     QSEQRAREVS HLEEELRKVQ ACLSQSQNFL EEMRAKNTSQ ETMLRDLQEK INQQENSLTL
     EKLKLALADL EKQRDCSQDL LRKREHHIEQ LNEKLSKIEK ESKTLLSALE LTKKEYEELN
     EEKTQFSHWK SENEKLLYQM EAEKESLQSK INHLETCLKT QQIKSHEYNE RIRTLELERD
     NLSVEMRNLC SMVDSKTREA EMQKQAYEEL QQKAELSDQK HKKEIENLCL QTSQLTGQVE
     DLEQKLQLLS RELMDKAQLY QDLQAEYENL RDLLKSKDSS LSQGDHQRSC LAFEQQSAMS
     TSFVNAMGEQ GSSSSGRSQC LLDADQSPKS SAILHNRVVS LGFSLESQKQ MNSNLQKQCE
     ELVHIKGEIE ENLIKAEQMH ESFVAETSQR ICKLQEDTSV HQNVVAESLV ALEHKEKELQ
     LWKARLESEQ VEIEELKKSN QLLEDSRKEL QLLSETLGSE KKEMSSVISL SKKEIEELTQ
     ENGTLKEINE ILNQEKMNLV QKNEKFSNCI EEQEKSISEL SDQYKQEKLI LLQRCEETRS
     AFEDLSEKYK AAQEKNLRLE CLLNECNSVC ESRKNELEQL KETFAKEHQE FLTKLTFAEE
     QNQKLILEFE VVQQALKSEI RDLHSSSKSE ADGLRQETMT LKEEQNKMQK EVNDLLQENE
     QLTKLTKTIH EGQHLKLEPL RDPVTERENE INTCNFQLQM DLGVRDIAPN NYNAQMVQLE
     ALIRNTELKL QESEKDKECL QQELQTLRGE LGAGNVQDCS SQEMSGLMNC EVDAEGKYSA
     VLCELSPRQG DSAHSQCSLQ AALSKLHELE KMCEMLQVEK LQLVSELKDS RAECITATSR
     MAEEVEKLVN EMKMLNDENS LPQAEPVGEM LASEFDRQQN EQTPVSLNPL DDSNSYEQLT
     LSNKEVQTHF AELQEKFSSL QSEHKILHDQ RCQMSSKMSE LRSYVDTLKA ENSALSVNLR
     NLQGDLAKGM KPEERILSLS SCVTNSPSET SFGEYSFHKD VLEQTGDTSF LSNLGESVSA
     NASLEEETLT MKEAPATLER SVEELKTLCQ GYLQSLKNLQ EKMESQAMMK DKEIQELRQL
     LSSERTELDR LRKQYLSQNE QWQQKLTSVT LEMESKLAAE KQQTEHLSLE LEVARLQLQG
     LELTSQSWLG ADIDDAIQNH QNGSCDIKES EEYTSEITEK TPKQDSHQIC EEVVQECLSV
     ESEETTGSPL VPRGAREVPS ETNYETAVGD QSQGCPEHTY ELSTGGSCAL SPVEFVENQV
     SVQTLQLQVK EALNENLRLL HAIEDRDRKV ENLLNEIKEL DSKLDLQELQ LKTKIETCLQ
     LEKIVEELQK EKCNLSVKSE SFSCGDQELG LRVETSLRSN LEMGTDDSSQ EVLKENIAKE
     DDNWKERFLD VENELNRMKA ENARIEHRAL TMEADLEVAQ TEKLCLEKDN GNSQKVIIHL
     EEELSVATSE RNRLHGELDA VTKENKTLAQ MSEVMKEKVQ ALEAEVRDRA AALQTLSLQV
     SELSENKRNL QEQLRRLEGD SQTLSSAAQE LESQVRRLDK EKESLARESE SLQAKLSELD
     QERLTVSRAL EAALMERDEF AERLGSTQEE VHQLRKGMEK LRVRIEADEK KQLHVLGKLK
     GSERDNDVLR DKVEGLQREL QMSEENQELV VLDAENAKAE METLRAQLDE LAESLRGSQV
     DLAVLRSEKG DLTKQLQEKQ GQVSELDGLL SSLKSLLEEK EQARAQMQEE SKTAVEMIQA
     QLRELTEEVA ALCQDQEPPR AEEQNLDAPG NEVPRLRGSI GRLRARVEAD REKQLHVLQQ
     LKESECHADL LKGSVESLER ELELSGRSQE HAVREAKDSR AEVETLKAEI QQIAQNLRDL
     EVDLVNTKSE KENLTKGLQE EQARVSELEI LNSSLENLLQ EKEHQNVQIK EESEVAVEML
     QAQLKVLDEK MITLCNDQAA CKRKEQSLSS QVDSLELEKA QLLQDLEGAK NNYIILQSSV
     NGLMQEVEDG KQELERKDEE LSQLKGQVQD QEQLASQLSQ VEGERQLWQK QKAEMGTLAV
     ELEQKARELQ SKNHTLQESL EGLQNSCREL ESELTLTKVE NMSLVEKVNT MIVKEAELQG
     EMQNMVEKTT ELKEEFSGEK NRLAAELNVL SEEIKSSKTD HLKYVDQLKK ENERAQGKIK
     LLLKSCRQLE EEKKMLQKEL SDLEAAQKQK TGALVDVNVD ELMAEIRELK ETLEEKAKEA
     DEYLDKYCSL LISYEKLEKA KEMLETQVTR LSSQHPKHGL SGSSLQSSTT PEPCPAPSVG
     EGRSSSGRSK ASGKRQRCSG NWESRGGLTP STPETFPKKS RKVVKSGSIH PAEDEEEFEP
     EGLSEVVKKG FADIPTGKTS PYVLRRTTVA TRTSPRLAAL KSALSPLSVG KENLEESSKP
     TASGSRSQKV KVAQQSPVGS AEPTVTSVSV RHFSGRSPAD SPGDGPRTRR SPLVPSPDAR
     PQPMNSENCR VQ
//
DBGET integrated database retrieval system