ID G5BVA0_HETGA Unreviewed; 354 AA.
AC G5BVA0;
DT 14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2011, sequence version 1.
DT 24-JAN-2024, entry version 37.
DE SubName: Full=THUMP domain-containing protein 1 {ECO:0000313|EMBL:EHB13211.1};
GN Name=THUMPD1 {ECO:0000313|EMBL:JAN95963.1};
GN ORFNames=GW7_04736 {ECO:0000313|EMBL:EHB13211.1};
OS Heterocephalus glaber (Naked mole rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae;
OC Heterocephalus.
OX NCBI_TaxID=10181 {ECO:0000313|EMBL:EHB13211.1, ECO:0000313|Proteomes:UP000006813};
RN [1] {ECO:0000313|EMBL:EHB13211.1, ECO:0000313|Proteomes:UP000006813}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21993625; DOI=10.1038/nature10533;
RA Kim E.B., Fang X., Fushan A.A., Huang Z., Lobanov A.V., Han L.,
RA Marino S.M., Sun X., Turanov A.A., Yang P., Yim S.H., Zhao X.,
RA Kasaikina M.V., Stoletzki N., Peng C., Polak P., Xiong Z., Kiezun A.,
RA Zhu Y., Chen Y., Kryukov G.V., Zhang Q., Peshkin L., Yang L., Bronson R.T.,
RA Buffenstein R., Wang B., Han C., Li Q., Chen L., Zhao W., Sunyaev S.R.,
RA Park T.J., Zhang G., Wang J., Gladyshev V.N.;
RT "Genome sequencing reveals insights into physiology and longevity of the
RT naked mole rat.";
RL Nature 479:223-227(2011).
RN [2] {ECO:0000313|EMBL:JAN95963.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Kidney {ECO:0000313|EMBL:JAN95963.1};
RA Bens M., Sahm A., Jahn N., Morhart M., Holtze S., Hildebrandt T.B.,
RA Platzer M., Szafranski K.;
RT "FRAMA: From RNA-seq data to annotated mRNA assemblies.";
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; JH172081; EHB13211.1; -; Genomic_DNA.
DR EMBL; GEBF01007669; JAN95963.1; -; Transcribed_RNA.
DR AlphaFoldDB; G5BVA0; -.
DR STRING; 10181.G5BVA0; -.
DR Ensembl; ENSHGLT00000001265; ENSHGLP00000001223; ENSHGLG00000000952.
DR Ensembl; ENSHGLT00100021998; ENSHGLP00100021772; ENSHGLG00100016023.
DR eggNOG; KOG3943; Eukaryota.
DR InParanoid; G5BVA0; -.
DR OMA; MNEKACV; -.
DR Proteomes; UP000006813; Unassembled WGS sequence.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006400; P:tRNA modification; IEA:InterPro.
DR CDD; cd11717; THUMP_THUMPD1_like; 1.
DR Gene3D; 3.30.2300.10; THUMP superfamily; 1.
DR InterPro; IPR004114; THUMP_dom.
DR InterPro; IPR040183; THUMPD1-like.
DR PANTHER; PTHR13452; THUMP DOMAIN CONTAINING PROTEIN 1-RELATED; 1.
DR PANTHER; PTHR13452:SF10; THUMP DOMAIN-CONTAINING PROTEIN 1; 1.
DR Pfam; PF02926; THUMP; 1.
DR SMART; SM00981; THUMP; 1.
DR SUPFAM; SSF143437; THUMP domain-like; 1.
DR PROSITE; PS51165; THUMP; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000006813};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00529}.
FT DOMAIN 146..253
FT /note="THUMP"
FT /evidence="ECO:0000259|PROSITE:PS51165"
FT REGION 1..36
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 270..354
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 282..299
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 300..317
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 318..346
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 354 AA; 39773 MW; DECC4378484D56B8 CRC64;
MAAPVQQPPQ LGGGKRKGKA QYVQAKRARR CDAGGPRQLE PGVQGILITC NMNERKCVEE
AYSLLNEYGD DLYGPEKFTD KDQQLSGSEG EDDVEAALKK EVGDIKASTE KRLRRFQSVE
SGANNVVFIR TLGIEPEKLV HHILQDVYKT KKKKTRVILR MLPISGTCKA FLEDMKKYAE
TFLEPWFKAP NKGTFQIVYK SRNNSHMNRE EVIKELAGIV GSLNSENKVD LTNPQYTVVV
EIIKAVCCLS VVKDYVLFRK YNLQEVVKTT KDPSQLPSKL GNEKEAKLET DDKLNQNDPK
EGESNQQVVP QNNEEELGET KPSSETQVEC EGGDKPEPHR QIQEGSKSNE NDLS
//
