ID G5BW95_HETGA Unreviewed; 227 AA.
AC G5BW95;
DT 14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2011, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE RecName: Full=Sperm-associated antigen 7 {ECO:0000256|PIRNR:PIRNR037943};
GN Name=SPAG7 {ECO:0000313|EMBL:JAN99139.1};
GN ORFNames=GW7_04609 {ECO:0000313|EMBL:EHB13552.1};
OS Heterocephalus glaber (Naked mole rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae;
OC Heterocephalus.
OX NCBI_TaxID=10181 {ECO:0000313|EMBL:EHB13552.1, ECO:0000313|Proteomes:UP000006813};
RN [1] {ECO:0000313|EMBL:EHB13552.1, ECO:0000313|Proteomes:UP000006813}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21993625; DOI=10.1038/nature10533;
RA Kim E.B., Fang X., Fushan A.A., Huang Z., Lobanov A.V., Han L.,
RA Marino S.M., Sun X., Turanov A.A., Yang P., Yim S.H., Zhao X.,
RA Kasaikina M.V., Stoletzki N., Peng C., Polak P., Xiong Z., Kiezun A.,
RA Zhu Y., Chen Y., Kryukov G.V., Zhang Q., Peshkin L., Yang L., Bronson R.T.,
RA Buffenstein R., Wang B., Han C., Li Q., Chen L., Zhao W., Sunyaev S.R.,
RA Park T.J., Zhang G., Wang J., Gladyshev V.N.;
RT "Genome sequencing reveals insights into physiology and longevity of the
RT naked mole rat.";
RL Nature 479:223-227(2011).
RN [2] {ECO:0000313|EMBL:JAN99139.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Kidney {ECO:0000313|EMBL:JAN99139.1};
RA Bens M., Sahm A., Jahn N., Morhart M., Holtze S., Hildebrandt T.B.,
RA Platzer M., Szafranski K.;
RT "FRAMA: From RNA-seq data to annotated mRNA assemblies.";
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PIRNR:PIRNR037943}.
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DR EMBL; JH172199; EHB13552.1; -; Genomic_DNA.
DR EMBL; GEBF01004493; JAN99139.1; -; Transcribed_RNA.
DR RefSeq; XP_004857377.1; XM_004857320.2.
DR AlphaFoldDB; G5BW95; -.
DR GeneID; 101723171; -.
DR KEGG; hgl:101723171; -.
DR CTD; 9552; -.
DR eggNOG; ENOG502QW1E; Eukaryota.
DR InParanoid; G5BW95; -.
DR OMA; NGGFIAM; -.
DR OrthoDB; 2912385at2759; -.
DR Proteomes; UP000006813; Unassembled WGS sequence.
DR Bgee; ENSHGLG00000009748; Expressed in heart and 10 other cell types or tissues.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003676; F:nucleic acid binding; IEA:UniProtKB-UniRule.
DR CDD; cd02636; R3H_sperm-antigen; 1.
DR Gene3D; 3.30.1370.50; R3H-like domain; 1.
DR InterPro; IPR001374; R3H_dom.
DR InterPro; IPR036867; R3H_dom_sf.
DR InterPro; IPR034068; R3H_sperm-antigen.
DR InterPro; IPR017330; SPAG7.
DR PANTHER; PTHR13498; SPERM ASSOCIATED ANTIGEN 7; 1.
DR PANTHER; PTHR13498:SF3; SPERM-ASSOCIATED ANTIGEN 7; 1.
DR Pfam; PF01424; R3H; 1.
DR PIRSF; PIRSF037943; Sperm-assoc_antigen_PAG7; 1.
DR SMART; SM00393; R3H; 1.
DR SUPFAM; SSF82708; R3H domain; 1.
DR PROSITE; PS51061; R3H; 1.
PE 4: Predicted;
KW Nucleus {ECO:0000256|PIRNR:PIRNR037943};
KW Reference proteome {ECO:0000313|Proteomes:UP000006813}.
FT DOMAIN 46..109
FT /note="R3H"
FT /evidence="ECO:0000259|PROSITE:PS51061"
FT REGION 1..46
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 118..160
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 18..46
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 118..144
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 227 AA; 26032 MW; F75B0E814A7CAC05 CRC64;
MADLLGSILS SMEKPPSLGD QETRRKAREQ ATRLKKLQEQ EKQQKVEFRK RMEKEVSDFI
QDSGQIKKKF QPMNKIERSI LHDVVEVAGL TSFSFGEDDD CRYVMIFKKE FAPSDEELES
YRHGEEWDPQ KAEEKRKLKE LAQQQEEEAA QQGPVVVSPA SDYKDKYSHL IGKGAAKDAA
HMLEANKTYG CVPVANKRDT RSIEEAMNEI RAKKRLRQSG EELPPTS
//
