ID G5BZY1_HETGA Unreviewed; 1106 AA.
AC G5BZY1;
DT 14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2011, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE SubName: Full=RNA-binding protein 6 {ECO:0000313|EMBL:EHB14823.1};
DE Flags: Fragment;
GN ORFNames=GW7_19936 {ECO:0000313|EMBL:EHB14823.1};
OS Heterocephalus glaber (Naked mole rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae;
OC Heterocephalus.
OX NCBI_TaxID=10181 {ECO:0000313|EMBL:EHB14823.1, ECO:0000313|Proteomes:UP000006813};
RN [1] {ECO:0000313|EMBL:EHB14823.1, ECO:0000313|Proteomes:UP000006813}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21993625; DOI=10.1038/nature10533;
RA Kim E.B., Fang X., Fushan A.A., Huang Z., Lobanov A.V., Han L.,
RA Marino S.M., Sun X., Turanov A.A., Yang P., Yim S.H., Zhao X.,
RA Kasaikina M.V., Stoletzki N., Peng C., Polak P., Xiong Z., Kiezun A.,
RA Zhu Y., Chen Y., Kryukov G.V., Zhang Q., Peshkin L., Yang L., Bronson R.T.,
RA Buffenstein R., Wang B., Han C., Li Q., Chen L., Zhao W., Sunyaev S.R.,
RA Park T.J., Zhang G., Wang J., Gladyshev V.N.;
RT "Genome sequencing reveals insights into physiology and longevity of the
RT naked mole rat.";
RL Nature 479:223-227(2011).
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DR EMBL; JH172617; EHB14823.1; -; Genomic_DNA.
DR AlphaFoldDB; G5BZY1; -.
DR STRING; 10181.G5BZY1; -.
DR eggNOG; KOG0154; Eukaryota.
DR InParanoid; G5BZY1; -.
DR Proteomes; UP000006813; Unassembled WGS sequence.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR CDD; cd12563; RRM2_RBM6; 1.
DR Gene3D; 3.30.70.330; -; 2.
DR Gene3D; 2.160.20.80; E3 ubiquitin-protein ligase SopA; 1.
DR InterPro; IPR000467; G_patch_dom.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR041591; OCRE.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR034125; RBM6_RRM2.
DR InterPro; IPR000504; RRM_dom.
DR PANTHER; PTHR13948; RNA-BINDING PROTEIN; 1.
DR PANTHER; PTHR13948:SF22; RNA-BINDING PROTEIN 6; 1.
DR Pfam; PF01585; G-patch; 1.
DR Pfam; PF17780; OCRE; 1.
DR SMART; SM00360; RRM; 2.
DR SUPFAM; SSF141571; Pentapeptide repeat-like; 1.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 2.
DR PROSITE; PS50174; G_PATCH; 1.
DR PROSITE; PS50102; RRM; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000006813};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW ProRule:PRU00176}.
FT DOMAIN 442..522
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 1034..1080
FT /note="G-patch"
FT /evidence="ECO:0000259|PROSITE:PS50174"
FT REGION 1..174
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 219..261
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 284..329
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 342..376
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 418..440
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 558..633
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 725..771
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 798..929
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 992..1089
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 959..986
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 98..121
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 128..174
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 227..261
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 292..329
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 342..370
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 418..439
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 558..577
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 578..633
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 726..755
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 756..771
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 808..847
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 992..1032
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EHB14823.1"
SQ SEQUENCE 1106 AA; 126917 MW; 86D2D10CE7FE7FA2 CRC64;
YSGSQEERFA PGWNRDYPPP PLKSHAQERH SGNFPGRDSL PFDFQGHSGP PFANVEEHSF
SYGARDGPHG DYRGGEGPGH DFRGGDFSST DFQSRDSSQL DFRGRDIHSG DFRDREGPPM
DYRGGDGTSM DFRGRETPHM NYRDRDTHTV DFRGRDPPSD FRGRGTYDLD FRGRDGSHAD
FRGRDLSDLD FRTRDQSRSD FRNRDVSDLD FRDKDGTQVD FRARGSGTTD LDFRDRDTPH
SDFRGRHRSR TDQDFRGRDM GPCVEFKDRE MPPVDPKLLD YLQPSTQDRE HSCMNVNKRE
ESKYDHTAER PSFGIQKGEF EHSETREGET QGVAFEHELP SDFQKSQSPI QDQDKSQLSG
AEQQSSDAGL FKQKGDLDFL GQQDTDYRSM EYRDVDHRLP GSQIFGYGQN KTFLEGKTAR
DAQRDLQDQD YRTGPSEEKP SRLIRLSGVP ENATKEEILN AFRTANGMPV RELQLKEYNT
GYDYGYVCVE FSLLEDAIGC MEANQGTVMI HDKEITLEYV PNLDFWYCKR CKASTGGHRS
SCSFCKCPKE EAKQELITYP QPQKTSIPAS LEKQPSQSSR PAEKESESRK QEEGQEPRLG
HQKKEAERYL PHSRREGLAF RRDREKESWS GEMRQDGESK TIMLKRIYRS TPPEVIVEVL
EPYVHLTTAN VRIIKNRTGP MGHTYGFIDL DSHAEALRVV KILQNLDPPF SIDGKMVAVN
LATGKRRNDS GDHSDHMHYY QGKKYFRDRR GGGRNSDWSS DTNRQGQQSS SDCYIYDSAT
GYYYDPLAGT YYDPNTQQEV YVPQDPGSPE EEEIKEKKPT SQGKSSSKKE MPKRDSKEKK
DRAVTKFQEV ASEGTSPPED VFKKPLPPTV KKEESPPPPK VVNPLIGLLG EYGGDSDYEE
EEEEQTAPLQ PRTTQPQQRE ELTKKENEED KLTDWNKLAC LLCRRQFPNK EVLIKHQQLS
DLHKQNLEIH RKIKQSEQEL AYLERREREG RFKERGNDRK EKLQSFDCPE RKRIKYSRET
DSDRKPVDKE DINTSSKGGC VQQPTGWRKG AGLGFGHPGL GSSEETEGRM RGPGVGLPGR
TSKRQSNETY RDAVRRVMFA RYKELD
//
