ID G5C2C5_HETGA Unreviewed; 1790 AA.
AC G5C2C5;
DT 14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2011, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE SubName: Full=Laminin subunit beta-1 {ECO:0000313|EMBL:EHB15686.1};
DE Flags: Fragment;
GN ORFNames=GW7_15853 {ECO:0000313|EMBL:EHB15686.1};
OS Heterocephalus glaber (Naked mole rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae;
OC Heterocephalus.
OX NCBI_TaxID=10181 {ECO:0000313|EMBL:EHB15686.1, ECO:0000313|Proteomes:UP000006813};
RN [1] {ECO:0000313|EMBL:EHB15686.1, ECO:0000313|Proteomes:UP000006813}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21993625; DOI=10.1038/nature10533;
RA Kim E.B., Fang X., Fushan A.A., Huang Z., Lobanov A.V., Han L.,
RA Marino S.M., Sun X., Turanov A.A., Yang P., Yim S.H., Zhao X.,
RA Kasaikina M.V., Stoletzki N., Peng C., Polak P., Xiong Z., Kiezun A.,
RA Zhu Y., Chen Y., Kryukov G.V., Zhang Q., Peshkin L., Yang L., Bronson R.T.,
RA Buffenstein R., Wang B., Han C., Li Q., Chen L., Zhao W., Sunyaev S.R.,
RA Park T.J., Zhang G., Wang J., Gladyshev V.N.;
RT "Genome sequencing reveals insights into physiology and longevity of the
RT naked mole rat.";
RL Nature 479:223-227(2011).
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00460}.
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DR EMBL; JH173070; EHB15686.1; -; Genomic_DNA.
DR STRING; 10181.G5C2C5; -.
DR eggNOG; KOG0994; Eukaryota.
DR InParanoid; G5C2C5; -.
DR Proteomes; UP000006813; Unassembled WGS sequence.
DR CDD; cd22300; cc_LAMB1_C; 1.
DR CDD; cd00055; EGF_Lam; 13.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 2.10.25.10; Laminin; 9.
DR Gene3D; 2.170.300.10; Tie2 ligand-binding domain superfamily; 2.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR013015; Laminin_IV_B.
DR InterPro; IPR008211; Laminin_N.
DR InterPro; IPR002049; LE_dom.
DR PANTHER; PTHR10574:SF233; LAMININ SUBUNIT BETA-1; 1.
DR PANTHER; PTHR10574; NETRIN/LAMININ-RELATED; 1.
DR Pfam; PF00053; Laminin_EGF; 13.
DR Pfam; PF21199; LAMININ_IV_B; 1.
DR Pfam; PF00055; Laminin_N; 1.
DR PRINTS; PR00011; EGFLAMININ.
DR SMART; SM00181; EGF; 9.
DR SMART; SM00180; EGF_Lam; 13.
DR SMART; SM00136; LamNT; 1.
DR SUPFAM; SSF57196; EGF/Laminin; 13.
DR SUPFAM; SSF46579; Prefoldin; 1.
DR PROSITE; PS01248; EGF_LAM_1; 5.
DR PROSITE; PS50027; EGF_LAM_2; 11.
DR PROSITE; PS51116; LAMININ_IVB; 1.
DR PROSITE; PS51117; LAMININ_NTER; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00460};
KW Laminin EGF-like domain {ECO:0000256|ARBA:ARBA00023292,
KW ECO:0000256|PROSITE-ProRule:PRU00460};
KW Reference proteome {ECO:0000313|Proteomes:UP000006813};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 35..274
FT /note="Laminin N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51117"
FT DOMAIN 275..338
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 402..461
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 462..513
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 553..771
FT /note="Laminin IV type B"
FT /evidence="ECO:0000259|PROSITE:PS51116"
FT DOMAIN 777..824
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 825..870
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 871..920
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 921..979
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 980..1031
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 1032..1087
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 1088..1135
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 1136..1182
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT COILED 1254..1316
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1462..1489
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1544..1778
FT /evidence="ECO:0000256|SAM:Coils"
FT DISULFID 304..313
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 432..441
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 485..494
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 497..511
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 777..789
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 779..796
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 798..807
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 825..837
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 827..844
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 846..855
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 890..899
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 950..959
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 1004..1013
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 1032..1044
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 1060..1069
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 1088..1100
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 1090..1107
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 1109..1118
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 1136..1148
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 1138..1155
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 1157..1166
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EHB15686.1"
SQ SEQUENCE 1790 AA; 196890 MW; F55689A5BC8DD6B8 CRC64;
CLPPPTLPLA PPAALCGPGV HAQDAQEPEF SYGCAEGSCY PATGDLLIGR AQKLSVTSTC
GLHQPEPYCI VSHLQEDKKC FICNSQDPYH ETLNPDSHLI ENVVTTFAPN RLKIWWQSES
GVENVTIQLD LEAEFHFTHL IMTFKSFRPA AMLIERSSDF GRTWGVYRYF AYDCESSFPG
ISTGPMKRVD EIICDSRYSD IEPSTEGEVI FRALDPAFKI EDPYSPRIQN LLKITNLRIK
FVKLHTLGDN LLDSRMEIRE KYYYAVYDMV VRGNCFCYGH ASECAPVDGF NEEVEGMVHG
HCMCRHNTKG LNCELCMDFY HDLPWRPAEG RNSNACKKCS CNEHSSACHF DMAVYLATGN
VTGGVCDGCQ HNTMGRSCEQ CKPFYYQHPE RDIRAPNICE RCTCDPAGSQ NGGICDSYTD
FSTGLIAGQC RCKLHVEGEH CDVCKEGFYD LNAEDPLGCK SCACSPLGTI PGGNPCDSGT
GSCYCKRLVT GQHCDQCLPQ HWGLSNDLDG CRPCDCDVGG ALNNSCSAES GQCSCRPHLI
GRQCSEVESG YYFTTLDHYI YEAEGASLGP GVSVVERQYI QDRIPSWTGA GFVRVPEGAY
LEFFIDNIPF SMEYEILIRY EPQLPDHWEK AVITVQRPGR IPTSSRCGNT VPDDDNQVVS
LSPGSRYIVL PRPVCLEKGL NYTVRLELPQ YTSSDSNVES PYTFIDSLAL IPYCKSLDIF
TVGGSGDGVV TNSAWETFQR YRCLENSRSV VKTPMTDVCR SIIFSISALL HQAGLACECD
PQGSLSSVCD PNGGQCQCRP NVVGRTCDRC APGTFGFGPS GCKPCDCHLQ GSVSASCDAN
TGQCHCFPGV YSRQCDQCLP GYWGFPSCQP CQCNGHAEDC DTATGACLRC QDYTMGHNCE
RCLAGYYGDP IIGSGDHCRP CPCPDGPDSG RQFARSCYQD PVTLQLACVC EPGYIGSRCD
QCASGFFGNP LDIGGLCQPC QCHHNIDTSD PEGCDKKTGR CLKCLYHTEG DQCQFCRSGY
YGDALRQDCR KCVCNILGTV QERCNGSDCQ CNQATGQCAC LPNVIGQNCD RCAPNTWQLA
SGTGCEQCSC NAAHSFGPSC NEFTGQCQCM PGFGGRTCSE CQELFWGDPN VECRACDCDP
RGIETPQCHQ SSGRCVCVEG VEGPRCDKCT RGYSGVFPNC TPCHQCFALW DVIIAELTNR
THKFLEKAKA LKISGVIGPY QETVDSVEKK INEIKEILAQ SPAAEPLKNI GNLFEEAEKL
TKDVTEKMAQ VEVKLSDTAA QSNSTARELD LLQAEAESLD NTVKELAEQL EFIKNSDIRG
ALDSITKYFQ MSVEAEERVN ASTTDPNSTV EQSALMRDRV EDVMLEQESQ FREKQEDQAR
LLDELAGKLQ SLDLSAAAEL VCGTPPGADC SETECGGPNC RADDGQKKCG GPGCGGLVTV
AHSAWQKAMD FDRDVLGALA DVEQLSKMVS EAKLKADEAK QNAQDVLLKT NATRDKVGKS
NEELRNLIKE IRDFLTQDGA DLDSIETVAN EVLKMEMPST PQQLQNLTEE IREKVESLSQ
VEVILEQSAS DIARAEMLLE EAKRASQSAT SVKVTADMVK EALEEAEKAQ VAAEKAIKQA
DEDIQGTQNL LTSIESETAA SEETLSNASQ RINELERNVE ELKRKATQNS GEAEYIEKVV
YTVKQSADDV KKALDGELDE KYKKVENLIA KKTEESADAR RKAEMLQNEA KTLLAQANSK
LQMLKDLERK YEDNQKYLED KAQELVRLEG EVRSLLHDIS QQVAIYSTCL
//
