ID G5C473_HETGA Unreviewed; 137 AA.
AC G5C473;
DT 14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2011, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=Interferon-induced transmembrane protein 3 {ECO:0000313|EMBL:EHB16334.1};
GN ORFNames=GW7_07594 {ECO:0000313|EMBL:EHB16334.1};
OS Heterocephalus glaber (Naked mole rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae;
OC Heterocephalus.
OX NCBI_TaxID=10181 {ECO:0000313|EMBL:EHB16334.1, ECO:0000313|Proteomes:UP000006813};
RN [1] {ECO:0000313|EMBL:EHB16334.1, ECO:0000313|Proteomes:UP000006813}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21993625; DOI=10.1038/nature10533;
RA Kim E.B., Fang X., Fushan A.A., Huang Z., Lobanov A.V., Han L.,
RA Marino S.M., Sun X., Turanov A.A., Yang P., Yim S.H., Zhao X.,
RA Kasaikina M.V., Stoletzki N., Peng C., Polak P., Xiong Z., Kiezun A.,
RA Zhu Y., Chen Y., Kryukov G.V., Zhang Q., Peshkin L., Yang L., Bronson R.T.,
RA Buffenstein R., Wang B., Han C., Li Q., Chen L., Zhao W., Sunyaev S.R.,
RA Park T.J., Zhang G., Wang J., Gladyshev V.N.;
RT "Genome sequencing reveals insights into physiology and longevity of the
RT naked mole rat.";
RL Nature 479:223-227(2011).
CC -!- SIMILARITY: Belongs to the CD225/Dispanin family.
CC {ECO:0000256|ARBA:ARBA00006843}.
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DR EMBL; JH173280; EHB16334.1; -; Genomic_DNA.
DR RefSeq; XP_004851801.1; XM_004851744.1.
DR AlphaFoldDB; G5C473; -.
DR STRING; 10181.G5C473; -.
DR Ensembl; ENSHGLT00100054967; ENSHGLP00100048123; ENSHGLG00100011390.
DR GeneID; 101722087; -.
DR KEGG; hgl:101722087; -.
DR eggNOG; ENOG502S9XK; Eukaryota.
DR InParanoid; G5C473; -.
DR OMA; AKFLNIC; -.
DR OrthoDB; 5322528at2759; -.
DR Proteomes; UP000006813; Unassembled WGS sequence.
DR Bgee; ENSHGLG00000012557; Expressed in liver and 10 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR InterPro; IPR007593; CD225/Dispanin_fam.
DR PANTHER; PTHR13999; INTERFERON INDUCIBLE TRANSMEMBRANE PROTEIN; 1.
DR PANTHER; PTHR13999:SF4; INTERFERON-INDUCED TRANSMEMBRANE PROTEIN 3; 1.
DR Pfam; PF04505; CD225; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000006813};
KW Transmembrane {ECO:0000256|SAM:Phobius, ECO:0000313|EMBL:EHB16334.1};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 58..80
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 110..133
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 137 AA; 14831 MW; D7E6FC598F986C2C CRC64;
MSHTGPAFFS HANVGLPPNY EKIQEEHEVA VLGGTHGPVP AASTVINIRS DIAVPDHVVW
SLFNTIFMNT CCLGFIAFAY SIKSRDRKMV GDVIGAQSYA STAKCLNISA LVLSITLTIT
VIIVFAFTSV HLFKMMT
//
