ID   G5C561_HETGA            Unreviewed;       572 AA.
AC   G5C561;
DT   14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT   14-DEC-2011, sequence version 1.
DT   27-MAR-2024, entry version 31.
DE   SubName: Full=Nucleolar protein 9 {ECO:0000313|EMBL:EHB16672.1};
DE   Flags: Fragment;
GN   ORFNames=GW7_09151 {ECO:0000313|EMBL:EHB16672.1};
OS   Heterocephalus glaber (Naked mole rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae;
OC   Heterocephalus.
OX   NCBI_TaxID=10181 {ECO:0000313|EMBL:EHB16672.1, ECO:0000313|Proteomes:UP000006813};
RN   [1] {ECO:0000313|EMBL:EHB16672.1, ECO:0000313|Proteomes:UP000006813}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=21993625; DOI=10.1038/nature10533;
RA   Kim E.B., Fang X., Fushan A.A., Huang Z., Lobanov A.V., Han L.,
RA   Marino S.M., Sun X., Turanov A.A., Yang P., Yim S.H., Zhao X.,
RA   Kasaikina M.V., Stoletzki N., Peng C., Polak P., Xiong Z., Kiezun A.,
RA   Zhu Y., Chen Y., Kryukov G.V., Zhang Q., Peshkin L., Yang L., Bronson R.T.,
RA   Buffenstein R., Wang B., Han C., Li Q., Chen L., Zhao W., Sunyaev S.R.,
RA   Park T.J., Zhang G., Wang J., Gladyshev V.N.;
RT   "Genome sequencing reveals insights into physiology and longevity of the
RT   naked mole rat.";
RL   Nature 479:223-227(2011).
CC   -!- SIMILARITY: Belongs to the Clp1 family. NOL9/GRC3 subfamily.
CC       {ECO:0000256|ARBA:ARBA00011003}.
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DR   EMBL; JH173407; EHB16672.1; -; Genomic_DNA.
DR   AlphaFoldDB; G5C561; -.
DR   STRING; 10181.G5C561; -.
DR   eggNOG; KOG2750; Eukaryota.
DR   InParanoid; G5C561; -.
DR   Proteomes; UP000006813; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0051731; F:polynucleotide 5'-hydroxyl-kinase activity; IEA:InterPro.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   GO; GO:0006396; P:RNA processing; IEA:InterPro.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR045116; Clp1/Grc3.
DR   InterPro; IPR032319; CLP1_P.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR12755; CLEAVAGE/POLYADENYLATION FACTOR IA SUBUNIT CLP1P; 1.
DR   PANTHER; PTHR12755:SF3; POLYNUCLEOTIDE 5'-HYDROXYL-KINASE NOL9; 1.
DR   Pfam; PF16575; CLP1_P; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Kinase {ECO:0000256|ARBA:ARBA00022777};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000006813};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT   DOMAIN          174..304
FT                   /note="Polyribonucleotide 5'-hydroxyl-kinase Clp1 P-loop"
FT                   /evidence="ECO:0000259|Pfam:PF16575"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:EHB16672.1"
FT   NON_TER         572
FT                   /evidence="ECO:0000313|EMBL:EHB16672.1"
SQ   SEQUENCE   572 AA;  64082 MW;  4129C9594D80B4DF CRC64;
     GFTFSGVCRM TCLYGQVEVL GFVISQGQPA HDIFSAYTHS YLTINAVRYS MPEKSKKEIK
     REARACLRAH LNLEDRSWAT GNFSPLCSIV LLEHVKTTTI NFIASHPGLS TIFVQEKEAS
     QVTSECLVLG SVGIKREKRK RGLQLTESTL AALEELVSVS CEDSDGCPIV LVCGGQDVGK
     STFNRYLINQ LLNSISCVDY LECDLGQTEF TPPGCISLLN ITEPVLGPPY THQRTPQKMV
     YYGKLSCKNS FENYIDIIKY VFSAYKREAP LIINTMGWVS EEGLQLLIDL IRLLSPSHVV
     QFSSPKSKHM PPLTPDYVAD RDGLYTKSKS RLRSQGFCLP EFSDSMEFAD EEKDSPVLFA
     EHKLLSVFSE FSFRKTPRNR DSHNRIFRDL TVLAYLAQLL PPVPKPLSPL HGLTPYQVPF
     NAIALRITHS DVAPTHILYA VNGSWLGLCR ILDDIRGYSR GPILLAQTPI CDCVGFGVCR
     GIDMEKRLYH ILTPVPPEEL RSVNCLLVGA ISIPQCVFKS QHGLEGTIPY ITMDYNFKLP
     GASEKIGVRD SEKEQLPKGK LHPRSKFFRK MK
//