ID G5C6N2_HETGA Unreviewed; 187 AA.
AC G5C6N2;
DT 14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2011, sequence version 1.
DT 24-JAN-2024, entry version 19.
DE SubName: Full=Membrane protein FAM174B {ECO:0000313|EMBL:EHB17193.1};
GN ORFNames=GW7_03325 {ECO:0000313|EMBL:EHB17193.1};
OS Heterocephalus glaber (Naked mole rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae;
OC Heterocephalus.
OX NCBI_TaxID=10181 {ECO:0000313|EMBL:EHB17193.1, ECO:0000313|Proteomes:UP000006813};
RN [1] {ECO:0000313|EMBL:EHB17193.1, ECO:0000313|Proteomes:UP000006813}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21993625; DOI=10.1038/nature10533;
RA Kim E.B., Fang X., Fushan A.A., Huang Z., Lobanov A.V., Han L.,
RA Marino S.M., Sun X., Turanov A.A., Yang P., Yim S.H., Zhao X.,
RA Kasaikina M.V., Stoletzki N., Peng C., Polak P., Xiong Z., Kiezun A.,
RA Zhu Y., Chen Y., Kryukov G.V., Zhang Q., Peshkin L., Yang L., Bronson R.T.,
RA Buffenstein R., Wang B., Han C., Li Q., Chen L., Zhao W., Sunyaev S.R.,
RA Park T.J., Zhang G., Wang J., Gladyshev V.N.;
RT "Genome sequencing reveals insights into physiology and longevity of the
RT naked mole rat.";
RL Nature 479:223-227(2011).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
CC -!- SIMILARITY: Belongs to the FAM174 family.
CC {ECO:0000256|ARBA:ARBA00006986}.
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DR EMBL; JH173564; EHB17193.1; -; Genomic_DNA.
DR AlphaFoldDB; G5C6N2; -.
DR STRING; 10181.G5C6N2; -.
DR eggNOG; ENOG502S4RE; Eukaryota.
DR InParanoid; G5C6N2; -.
DR Proteomes; UP000006813; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR009565; FAM174-like.
DR PANTHER; PTHR28607; EXPRESSED PROTEIN; 1.
DR PANTHER; PTHR28607:SF3; MEMBRANE PROTEIN FAM174B; 1.
DR Pfam; PF06679; DUF1180; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000006813};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..187
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003475204"
FT TRANSMEM 49..71
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 187 AA; 20738 MW; 1446DBA77D55BE77 CRC64;
MTQLPLLISL LLLPVRNLNS NSSHLGVMSS GDALVTRLST LLRDLPTLKA AVVVACAFSA
LLIACLLLRV FRSGKRLRKT RKYDIITTPA ERVEMAPLNE EDDEDEDSTV FDIKYSYVTS
QPWNRIHQLS LARTMTTAVE PQGELVFCLT HEHCGSGCWV PLVLAGAAAD TDPPNPQHCR
HCNKDRE
//
