ID   G5C7U7_HETGA            Unreviewed;       468 AA.
AC   G5C7U7;
DT   14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT   14-DEC-2011, sequence version 1.
DT   24-JAN-2024, entry version 26.
DE   SubName: Full=RAB3A-interacting protein {ECO:0000313|EMBL:EHB17608.1};
DE   Flags: Fragment;
GN   ORFNames=GW7_11346 {ECO:0000313|EMBL:EHB17608.1};
OS   Heterocephalus glaber (Naked mole rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae;
OC   Heterocephalus.
OX   NCBI_TaxID=10181 {ECO:0000313|EMBL:EHB17608.1, ECO:0000313|Proteomes:UP000006813};
RN   [1] {ECO:0000313|EMBL:EHB17608.1, ECO:0000313|Proteomes:UP000006813}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=21993625; DOI=10.1038/nature10533;
RA   Kim E.B., Fang X., Fushan A.A., Huang Z., Lobanov A.V., Han L.,
RA   Marino S.M., Sun X., Turanov A.A., Yang P., Yim S.H., Zhao X.,
RA   Kasaikina M.V., Stoletzki N., Peng C., Polak P., Xiong Z., Kiezun A.,
RA   Zhu Y., Chen Y., Kryukov G.V., Zhang Q., Peshkin L., Yang L., Bronson R.T.,
RA   Buffenstein R., Wang B., Han C., Li Q., Chen L., Zhao W., Sunyaev S.R.,
RA   Park T.J., Zhang G., Wang J., Gladyshev V.N.;
RT   "Genome sequencing reveals insights into physiology and longevity of the
RT   naked mole rat.";
RL   Nature 479:223-227(2011).
CC   -!- SIMILARITY: Belongs to the SEC2 family.
CC       {ECO:0000256|ARBA:ARBA00025794}.
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DR   EMBL; JH173708; EHB17608.1; -; Genomic_DNA.
DR   AlphaFoldDB; G5C7U7; -.
DR   STRING; 10181.G5C7U7; -.
DR   eggNOG; KOG4324; Eukaryota.
DR   InParanoid; G5C7U7; -.
DR   Proteomes; UP000006813; Unassembled WGS sequence.
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR   CDD; cd21068; Rab11BD_RAB3IP; 1.
DR   Gene3D; 1.20.5.4880; -; 1.
DR   InterPro; IPR040351; RAB3IL/RAB3IP/Sec2.
DR   InterPro; IPR009449; Sec2_N.
DR   PANTHER; PTHR14430:SF2; RAB-3A-INTERACTING PROTEIN; 1.
DR   PANTHER; PTHR14430; RABIN3-RELATED; 1.
DR   Pfam; PF06428; Sec2p; 1.
DR   SUPFAM; SSF144284; Sec2 N-terminal region; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW   Reference proteome {ECO:0000313|Proteomes:UP000006813}.
FT   DOMAIN          183..252
FT                   /note="GDP/GTP exchange factor Sec2 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF06428"
FT   REGION          254..287
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          159..250
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:EHB17608.1"
SQ   SEQUENCE   468 AA;  52114 MW;  7C33B01941FC347B CRC64;
     LFYDEAFAMA NDPLEGFHEV NLASPTSPDL LSVYESGTQE QTTSASVIFR PHPSALCSTP
     VQANALDVSD LPTQPVYSPL RHLNCVEISN ISIHVTEPAS CVTSGVSSGI TKLTTRKDSC
     NAEREFLQGA TVTEASASSD DIFGLSTDSL SRLRSPSVLE VREKGYERLK EELAKAQREL
     KLKDEECERL SKVRDQLGQE LEELTASLFE EAHKMVREAN VKQATAEKQL KEAQGKIDVL
     QAEVAALKTL VLSSSPTSPT QEPLPGGKTP FKRGHTRNKS TSSAMSGSHQ DLSVIQPIVK
     DCKEADLSLY NEFRSWKDEP TMDRTCPFLD KIYQEDIFPC LTFSKSELAS AVLEAVENNT
     LSIEPVGLQP IRFVKASAVE CGGPKKCALT GQIKSCKHRI KLGDSSNYYY ISPFCRYRIT
     SVCNFFTYIR YIQQGLVKQQ DVDQMFWEVM QLRKEMSLAK LGYFKEEL
//