ID G5CBF0_HETGA Unreviewed; 315 AA.
AC G5CBF0;
DT 14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2011, sequence version 1.
DT 24-JAN-2024, entry version 45.
DE SubName: Full=Myeloid-associated differentiation marker {ECO:0000313|EMBL:EHB18861.1};
GN ORFNames=GW7_20161 {ECO:0000313|EMBL:EHB18861.1};
OS Heterocephalus glaber (Naked mole rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae;
OC Heterocephalus.
OX NCBI_TaxID=10181 {ECO:0000313|EMBL:EHB18861.1, ECO:0000313|Proteomes:UP000006813};
RN [1] {ECO:0000313|EMBL:EHB18861.1, ECO:0000313|Proteomes:UP000006813}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21993625; DOI=10.1038/nature10533;
RA Kim E.B., Fang X., Fushan A.A., Huang Z., Lobanov A.V., Han L.,
RA Marino S.M., Sun X., Turanov A.A., Yang P., Yim S.H., Zhao X.,
RA Kasaikina M.V., Stoletzki N., Peng C., Polak P., Xiong Z., Kiezun A.,
RA Zhu Y., Chen Y., Kryukov G.V., Zhang Q., Peshkin L., Yang L., Bronson R.T.,
RA Buffenstein R., Wang B., Han C., Li Q., Chen L., Zhao W., Sunyaev S.R.,
RA Park T.J., Zhang G., Wang J., Gladyshev V.N.;
RT "Genome sequencing reveals insights into physiology and longevity of the
RT naked mole rat.";
RL Nature 479:223-227(2011).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the MAL family. {ECO:0000256|ARBA:ARBA00034721}.
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DR EMBL; JH204767; EHB18861.1; -; Genomic_DNA.
DR RefSeq; XP_004866786.1; XM_004866729.2.
DR RefSeq; XP_004866787.1; XM_004866730.1.
DR AlphaFoldDB; G5CBF0; -.
DR STRING; 10181.G5CBF0; -.
DR Ensembl; ENSHGLT00100049777; ENSHGLP00100060425; ENSHGLG00100049464.
DR Ensembl; ENSHGLT00100054001; ENSHGLP00100053296; ENSHGLG00100049464.
DR Ensembl; ENSHGLT00100059038; ENSHGLP00100058409; ENSHGLG00100049464.
DR Ensembl; ENSHGLT00100060729; ENSHGLP00100029450; ENSHGLG00100049464.
DR Ensembl; ENSHGLT00100069404; ENSHGLP00100051682; ENSHGLG00100049464.
DR Ensembl; ENSHGLT00100071647; ENSHGLP00100051891; ENSHGLG00100049464.
DR Ensembl; ENSHGLT00100083101; ENSHGLP00100048852; ENSHGLG00100049464.
DR GeneID; 101698725; -.
DR KEGG; hgl:101698725; -.
DR CTD; 91663; -.
DR eggNOG; KOG4788; Eukaryota.
DR InParanoid; G5CBF0; -.
DR OMA; GGMADWC; -.
DR OrthoDB; 3818412at2759; -.
DR Proteomes; UP000006813; Unassembled WGS sequence.
DR Bgee; ENSHGLG00000008811; Expressed in ovary and 10 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR008253; Marvel.
DR InterPro; IPR047123; MYADM-like.
DR PANTHER; PTHR17068:SF3; MYELOID-ASSOCIATED DIFFERENTIATION MARKER; 1.
DR PANTHER; PTHR17068; MYELOID-ASSOCIATED DIFFERENTIATION MARKER MYADM FAMILY MEMBER; 1.
DR Pfam; PF01284; MARVEL; 2.
DR PROSITE; PS51225; MARVEL; 2.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|PROSITE-ProRule:PRU00581, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000006813};
KW Transmembrane {ECO:0000256|PROSITE-ProRule:PRU00581,
KW ECO:0000256|SAM:Phobius}; Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 34..53
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 60..83
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 95..118
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 130..150
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 162..184
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 196..216
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 236..256
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 24..156
FT /note="MARVEL"
FT /evidence="ECO:0000259|PROSITE:PS51225"
FT DOMAIN 161..312
FT /note="MARVEL"
FT /evidence="ECO:0000259|PROSITE:PS51225"
SQ SEQUENCE 315 AA; 34410 MW; 64ABBB988D0D9EDF CRC64;
MPVTVTRTTI TTTSSSTVVG SPRALTQPLG LLRLLQLVST CVAFSLVASV GAYTGPMGHW
AMFTWCFCFA VTLIVLVVEL AGLQAHFPLS WRNFPITYAC YAALFCLTSS IIYPTTYVQF
MSHGRSRDHA IAATTFSCVA CLAYATEVAW TRARPGEVTG YMATVPGLLK VLETFVACVI
FVFISDPYLY QRAPALEWCV AVYSICFILA AVAILLNLGE CTGVLPFPFP SFLSGLALLS
VLMYASALVL WPLYHFNEKY GGQPRRAWDS GCGSRHTHIV CTWDRKLAVA VLTGINLLAY
LADLAHSARL VFVKV
//
