ID G5E8Q5_MOUSE Unreviewed; 197 AA.
AC G5E8Q5;
DT 14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2011, sequence version 1.
DT 27-MAR-2024, entry version 79.
DE RecName: Full=DCN1-like protein {ECO:0000256|RuleBase:RU363131};
DE AltName: Full=Defective in cullin neddylation protein 1-like protein {ECO:0000256|RuleBase:RU363131};
GN Name=Dcun1d2 {ECO:0000313|Ensembl:ENSMUSP00000106462.2,
GN ECO:0000313|MGI:MGI:2142792};
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000106462.2, ECO:0000313|Proteomes:UP000000589};
RN [1] {ECO:0000313|Ensembl:ENSMUSP00000106462.2, ECO:0000313|Proteomes:UP000000589}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000106462.2,
RC ECO:0000313|Proteomes:UP000000589};
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [2] {ECO:0007829|PubMed:21183079}
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
RA Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
RA Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
RT "A tissue-specific atlas of mouse protein phosphorylation and expression.";
RL Cell 143:1174-1189(2010).
RN [3] {ECO:0000313|Ensembl:ENSMUSP00000106462.2}
RP IDENTIFICATION.
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000106462.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; NP_001036114.1; NM_001042649.1.
DR AlphaFoldDB; G5E8Q5; -.
DR SMR; G5E8Q5; -.
DR MaxQB; G5E8Q5; -.
DR PeptideAtlas; G5E8Q5; -.
DR ProteomicsDB; 331062; -.
DR Antibodypedia; 48901; 115 antibodies from 16 providers.
DR DNASU; 102323; -.
DR Ensembl; ENSMUST00000110838.8; ENSMUSP00000106462.2; ENSMUSG00000038506.14.
DR GeneID; 102323; -.
DR UCSC; uc009kxi.1; mouse.
DR AGR; MGI:2142792; -.
DR CTD; 55208; -.
DR MGI; MGI:2142792; Dcun1d2.
DR VEuPathDB; HostDB:ENSMUSG00000038506; -.
DR GeneTree; ENSGT00940000157453; -.
DR HOGENOM; CLU_047042_0_2_1; -.
DR OrthoDB; 169757at2759; -.
DR BioGRID-ORCS; 102323; 0 hits in 77 CRISPR screens.
DR ChiTaRS; Dcun1d2; mouse.
DR Proteomes; UP000000589; Chromosome 8.
DR Bgee; ENSMUSG00000038506; Expressed in knee joint and 222 other cell types or tissues.
DR ExpressionAtlas; G5E8Q5; baseline and differential.
DR Gene3D; 1.10.8.10; DNA helicase RuvA subunit, C-terminal domain; 1.
DR Gene3D; 1.10.238.10; EF-hand; 1.
DR InterPro; IPR014764; DCN-prot.
DR InterPro; IPR005176; PONY_dom.
DR InterPro; IPR009060; UBA-like_sf.
DR PANTHER; PTHR12281:SF16; DCN1-LIKE PROTEIN 2; 1.
DR PANTHER; PTHR12281; RP42 RELATED; 1.
DR Pfam; PF03556; Cullin_binding; 1.
DR Pfam; PF14555; UBA_4; 1.
DR SUPFAM; SSF46934; UBA-like; 1.
DR PROSITE; PS51229; DCUN1; 1.
PE 1: Evidence at protein level;
KW Proteomics identification {ECO:0007829|EPD:G5E8Q5,
KW ECO:0007829|MaxQB:G5E8Q5};
KW Reference proteome {ECO:0000313|Proteomes:UP000000589};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786}.
FT DOMAIN 60..197
FT /note="DCUN1"
FT /evidence="ECO:0000259|PROSITE:PS51229"
SQ SEQUENCE 197 AA; 22769 MW; 43302CA6F3339505 CRC64;
MHKLKSAQKD KVRQFMACTQ ASERTAIYCL TQNEWKLDEA TDSFFQNPEA FHRESMKSSV
DQKKLEQLYS RYKDPQDENK IGIDGIQQFC DDLSLDPASI SVLVIAWKFR AATQCEFSKK
EFVDGMTELG CDSTERLKAL LPRLEQELKD PAKFKDLYQF TFTFAKNPGQ KGLGASQKIN
SKGYLEPSPR FWKHDCR
//
