ID G5IEV5_9CLOT Unreviewed; 925 AA.
AC G5IEV5;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 24-JAN-2024, entry version 42.
DE RecName: Full=alpha-L-rhamnosidase {ECO:0000256|ARBA:ARBA00012652};
DE EC=3.2.1.40 {ECO:0000256|ARBA:ARBA00012652};
GN ORFNames=HMPREF9473_02032 {ECO:0000313|EMBL:EHI59965.1};
OS Hungatella hathewayi WAL-18680.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae; Hungatella.
OX NCBI_TaxID=742737 {ECO:0000313|EMBL:EHI59965.1, ECO:0000313|Proteomes:UP000005384};
RN [1] {ECO:0000313|EMBL:EHI59965.1, ECO:0000313|Proteomes:UP000005384}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WAL-18680 {ECO:0000313|EMBL:EHI59965.1,
RC ECO:0000313|Proteomes:UP000005384};
RG The Broad Institute Genome Sequencing Platform;
RA Earl A., Ward D., Feldgarden M., Gevers D., Finegold S.M., Summanen P.H.,
RA Molitoris D.R., Song M., Daigneault M., Allen-Vercoe E., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA Arachchi H.M., Berlin A., Brown A., Chapman S.B., Chen Z., Dunbar C.,
RA Freedman E., Gearin G., Gellesch M., Goldberg J., Griggs A., Gujja S.,
RA Heiman D., Howarth C., Larson L., Lui A., MacDonald P.J.P., Montmayeur A.,
RA Murphy C., Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T.,
RA Shenoy N., Sisk P., Stolte C., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Clostridium hathewayi WAL-18680.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Hydrolysis of terminal non-reducing alpha-L-rhamnose residues
CC in alpha-L-rhamnosides.; EC=3.2.1.40;
CC Evidence={ECO:0000256|ARBA:ARBA00001445};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EHI59965.1}.
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DR EMBL; ADLN01000040; EHI59965.1; -; Genomic_DNA.
DR RefSeq; WP_006780012.1; NZ_JH379027.1.
DR AlphaFoldDB; G5IEV5; -.
DR PATRIC; fig|742737.3.peg.2053; -.
DR HOGENOM; CLU_002926_1_1_9; -.
DR OrthoDB; 9761045at2; -.
DR Proteomes; UP000005384; Unassembled WGS sequence.
DR GO; GO:0030596; F:alpha-L-rhamnosidase activity; IEA:UniProtKB-EC.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 1.50.10.10; -; 1.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 2.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 2.60.420.10; Maltose phosphorylase, domain 3; 1.
DR InterPro; IPR008928; 6-hairpin_glycosidase_sf.
DR InterPro; IPR012341; 6hp_glycosidase-like_sf.
DR InterPro; IPR016007; Alpha_rhamnosid.
DR InterPro; IPR035396; Bac_rhamnosid6H.
DR InterPro; IPR035398; Bac_rhamnosid_C.
DR InterPro; IPR013737; Bac_rhamnosid_N.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR008902; Rhamnosid_concanavalin.
DR PANTHER; PTHR33307:SF10; ALPHA-L-RHAMNOSIDASE; 1.
DR PANTHER; PTHR33307; ALPHA-RHAMNOSIDASE (EUROFUNG); 1.
DR Pfam; PF05592; Bac_rhamnosid; 1.
DR Pfam; PF17389; Bac_rhamnosid6H; 1.
DR Pfam; PF17390; Bac_rhamnosid_C; 1.
DR Pfam; PF08531; Bac_rhamnosid_N; 1.
DR PIRSF; PIRSF010631; A-rhamnsds; 2.
DR SUPFAM; SSF48208; Six-hairpin glycosidases; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000005384}.
FT DOMAIN 142..282
FT /note="Bacterial alpha-L-rhamnosidase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF08531"
FT DOMAIN 358..457
FT /note="Alpha-L-rhamnosidase concanavalin-like"
FT /evidence="ECO:0000259|Pfam:PF05592"
FT DOMAIN 461..815
FT /note="Alpha-L-rhamnosidase six-hairpin glycosidase"
FT /evidence="ECO:0000259|Pfam:PF17389"
FT DOMAIN 817..884
FT /note="Alpha-L-rhamnosidase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF17390"
SQ SEQUENCE 925 AA; 104370 MW; 9955BAE97C5EB90F CRC64;
MLKVSEITVQ YLDHPVGLGE RPWFGWKLES DRRNVIQEAY CLEIGADAAC SQPVWQSGWV
ESQESVHVEA EGFAPESCTK YYVRVKVRDG QEESGFCEAA PFVMAILNQE EWQARFITAE
RPEDKDSSGS TCLRKEIRLS GEVESAFVCA TALGLYHFYI NGEKIGTDEM TPGWTSYKNH
LCYQTYEVTE YLKQGDNALG AMVGAGWYKG KMGFLHLRNN YGERAAFLMQ LLIRYRDGRE
EIVVTDDSWT GHDGPVTFSE IYDGETYDAR LEIDGWNLAE MGQAVESLAG QQEQVVESSA
GQQVQAVESL AGQQERAVNA SDWRPAEMLD FPMSALCAQA GSKVSVVETP PVKEILTTPQ
GDRVLDFGQN LTGRVQFKVR GNAGDQVRLH FFETLDAAGN VYTANLRTAK EEVTYICKGQ
GEELYHPYFS FQGFRYAHVI SWPGELCPED IEAQVLHSAM KETGDFQCSH PLVNQLHHNI
RWSMKGNFLD VPTDCPQRDE RMGWTGDAQI FCRTACYLMN TYTFFAKWLR DVAADQTPEG
GVPHVVPDII SGKEEDDWLL SQGTHSAAAW ADVAVINPWN LYLMYGDKTI LEEQYDSMKR
WIGFMRDHAV DYIWNYKLQF GDWVALDAEE GSYFGATPND LTCTAYFAHS TDLFARIAGI
LGRGEDAREY GELYEKIKEK FRRTFFQEDG KMTAMTQTAH IVALYFELVP EEYRMQTAAQ
LVKLLEKEQG HLVTGFVGTP YFCHALSRNG YVKEAYELLL KEDFPSWLYQ VKMGATTIWE
HWDGLKPDGT MWSPDMNSFN HYAYGAVGEW LYRVVLGIEA DERDPGYHHM IISPQTGDAF
AFAKGHYDSV YGTIKVHWEK GQQEGERRLY ITIPANTTAD IRLESGAVIA DADGLAFVDQ
AGVMTAVAGS GTYEISYRKG GEQSC
//
