ID G5IGP8_9CLOT Unreviewed; 354 AA.
AC G5IGP8;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 24-JAN-2024, entry version 43.
DE RecName: Full=Fido domain-containing protein {ECO:0000259|PROSITE:PS51459};
GN ORFNames=HMPREF9473_02676 {ECO:0000313|EMBL:EHI59369.1};
OS Hungatella hathewayi WAL-18680.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae; Hungatella.
OX NCBI_TaxID=742737 {ECO:0000313|EMBL:EHI59369.1, ECO:0000313|Proteomes:UP000005384};
RN [1] {ECO:0000313|EMBL:EHI59369.1, ECO:0000313|Proteomes:UP000005384}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WAL-18680 {ECO:0000313|EMBL:EHI59369.1,
RC ECO:0000313|Proteomes:UP000005384};
RG The Broad Institute Genome Sequencing Platform;
RA Earl A., Ward D., Feldgarden M., Gevers D., Finegold S.M., Summanen P.H.,
RA Molitoris D.R., Song M., Daigneault M., Allen-Vercoe E., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA Arachchi H.M., Berlin A., Brown A., Chapman S.B., Chen Z., Dunbar C.,
RA Freedman E., Gearin G., Gellesch M., Goldberg J., Griggs A., Gujja S.,
RA Heiman D., Howarth C., Larson L., Lui A., MacDonald P.J.P., Montmayeur A.,
RA Murphy C., Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T.,
RA Shenoy N., Sisk P., Stolte C., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Clostridium hathewayi WAL-18680.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EHI59369.1}.
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DR EMBL; ADLN01000060; EHI59369.1; -; Genomic_DNA.
DR RefSeq; WP_006780655.1; NZ_JH379027.1.
DR AlphaFoldDB; G5IGP8; -.
DR PATRIC; fig|742737.3.peg.2687; -.
DR HOGENOM; CLU_047250_0_0_9; -.
DR OrthoDB; 9813719at2; -.
DR Proteomes; UP000005384; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR Gene3D; 1.10.3290.10; Fido-like domain; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR003812; Fido.
DR InterPro; IPR036597; Fido-like_dom_sf.
DR InterPro; IPR040198; Fido_containing.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR13504; FIDO DOMAIN-CONTAINING PROTEIN DDB_G0283145; 1.
DR PANTHER; PTHR13504:SF38; PROTEIN ADENYLYLTRANSFERASE AQ_AA38-RELATED; 1.
DR Pfam; PF02661; Fic; 1.
DR Pfam; PF13412; HTH_24; 1.
DR SUPFAM; SSF140931; Fic-like; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51459; FIDO; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|PIRSR:PIRSR640198-2};
KW Nucleotide-binding {ECO:0000256|PIRSR:PIRSR640198-2};
KW Reference proteome {ECO:0000313|Proteomes:UP000005384}.
FT DOMAIN 101..243
FT /note="Fido"
FT /evidence="ECO:0000259|PROSITE:PS51459"
FT ACT_SITE 180
FT /evidence="ECO:0000256|PIRSR:PIRSR640198-1"
FT BINDING 184..191
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PIRSR:PIRSR640198-2"
FT BINDING 221..222
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PIRSR:PIRSR640198-2"
FT BINDING 229
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PIRSR:PIRSR640198-2"
FT SITE 57
FT /note="Important for autoinhibition of adenylyltransferase
FT activity"
FT /evidence="ECO:0000256|PIRSR:PIRSR640198-3"
SQ SEQUENCE 354 AA; 40038 MW; 21E00FEDEA074289 CRC64;
MENGYNPPFT MTEEITNLVI EIGDLTGQIT AYGELSKNPK LRRENRIKTI HSSLAIEQNT
LTLEQVTGVI EGKRVLAPQQ DIREVKNAYE AYEQMMHMNP CSVKDLLKVH KYMMEGLVEE
AGRFRSGNAG VYAGDVLIHA GTPAGYVPGL IQELFEWLKV SKLHPLIKGC IFHYEFEFIH
PFQDGNGRTG RLWHSLILRN WRKFFAWMPV ETMIYKNQSE YYAAINQANA DGSSTVFVEY
MLNMIKETLT EIVEQQQREQ LNFQNENVGT NVGVNVGVNV GTNVGVNAVT KSIGMKPEEK
LLALLRSDSR LTSQNLAETL GISKRQVERI LSNLKKEGRL ERVGSSKNGS WKVL
//
