ID   G5JN57_STRCG            Unreviewed;      1464 AA.
AC   G5JN57;
DT   25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT   25-JAN-2012, sequence version 1.
DT   27-MAR-2024, entry version 40.
DE   SubName: Full=Type VII secretion protein EssC {ECO:0000313|EMBL:EHI74005.1};
GN   Name=essC_2 {ECO:0000313|EMBL:EHI74005.1};
GN   ORFNames=STRCR_1392 {ECO:0000313|EMBL:EHI74005.1};
OS   Streptococcus criceti HS-6.
OC   Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC   Streptococcus.
OX   NCBI_TaxID=873449 {ECO:0000313|EMBL:EHI74005.1, ECO:0000313|Proteomes:UP000004322};
RN   [1] {ECO:0000313|EMBL:EHI74005.1, ECO:0000313|Proteomes:UP000004322}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=HS-6 {ECO:0000313|EMBL:EHI74005.1,
RC   ECO:0000313|Proteomes:UP000004322};
RA   Stanhope M.J., Durkin A.S., Hostetler J., Kim M., Radune D., Singh I.,
RA   Town C.D.;
RL   Submitted (JUL-2011) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EHI74005.1}.
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DR   EMBL; AEUV02000002; EHI74005.1; -; Genomic_DNA.
DR   RefSeq; WP_004226693.1; NZ_AEUV02000002.1.
DR   STRING; 873449.STRCR_1392; -.
DR   eggNOG; COG1674; Bacteria.
DR   OrthoDB; 9807790at2; -.
DR   Proteomes; UP000004322; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR023839; Firmicutes_EssC_C.
DR   InterPro; IPR002543; FtsK_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   NCBIfam; TIGR03928; T7_EssCb_Firm; 1.
DR   PANTHER; PTHR22683; SPORULATION PROTEIN RELATED; 1.
DR   PANTHER; PTHR22683:SF1; TYPE VII SECRETION SYSTEM PROTEIN ESSC; 1.
DR   Pfam; PF01580; FtsK_SpoIIIE; 2.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR   PROSITE; PS50901; FTSK; 2.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW   ProRule:PRU00289}; Membrane {ECO:0000256|SAM:Phobius};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW   ProRule:PRU00289}; Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        207..227
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        233..253
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          627..821
FT                   /note="FtsK"
FT                   /evidence="ECO:0000259|PROSITE:PS50901"
FT   DOMAIN          971..1161
FT                   /note="FtsK"
FT                   /evidence="ECO:0000259|PROSITE:PS50901"
FT   BINDING         647..654
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00289"
FT   BINDING         989..996
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00289"
SQ   SEQUENCE   1464 AA;  166368 MW;  3896DF9E9151F139 CRC64;
     MEIIVLRKTY RQVLTVPKTG ALRLSDQLSL SQTSEGVAYH TKEKTAPLTT AIRLGDLVVY
     PQPNNRRRYS IVGLSRVAVS MQPGSNLSSG SQVISLLLTK ADKGSWQLRN FGAPIYLNNH
     LTSQHQALPF GAEVAFGNSL LKVFPKEIWV SGAVKNETLL EVADSAYHYY DGYPDYHRSP
     RLIYHFNDDR LTVTAPPQEP HKPRNELLRM LVPPLVMIGV VILITVFQPR GLYILMSVAM
     SIVTAVFSVQ NYFRNKREYK QSLADRISAY RAYLSDKSIQ LTQLSNTQRR WQSYHYPTIQ
     ELDSLVQEFS RRIYEKIPQD EDFLSYRLGL GEVPTSYRLD YSQQERSGVK DPLEEEGFAL
     YEAHKTLTDM PVLATLKNGP VGYVGERSLV LEQLQLLVYQ LAVFQSYHDV QFITIMPEAE
     KDQWQWLRWL PHATLQDINV RGFIYNERTR DQILNRLMEI LRQRELQQKE AGANQELLHL
     PHYVVLVTDA SLIRDHVIME FFAKDPTALG CSLIFVQATI RSLPENVQTV IHLKDQATGE
     LVMAERRVKE QTFTLDHFPE GYDKERISRR LAPLNHLETL KSAIPNSVTF LEMYQVDRVE
     ELGIFERWQS HSPHNSLAVP LGLRGGEDYV KLDLHERAHG PHGLIAGTTG SGKSELIQSY
     ILSLAVNFHP HDVAFLLIDY KGGGMANLFK DLPHVLGTIT NLDGNQSMRA LASIRAENER
     RQRLFNEAGV NHIHAYQKKY EQGDVSEPLP HLIIISDEFA ELKSEQPDFI TQLVSTARVG
     RSLGVNLILA TQKPAGVVND QIWSNSNFRI ALKVADKADS QEMLHTPDAA TITQAGRAYL
     QVGNNEVYEL FQSAWSGADY QPDKEDQGIE DHTIFAINEL GQYEALNQDL SGLDEATDIR
     EVPTELEAVV QHIQQVTQEK HIAQLAQPWL PPLKTQIFLQ DLRPDRFQEL WQGDSRLEAI
     VGMVDIPSEQ RQTVGTYQLA DDGNLAIFGG PAMGKSTFLQ TIVMDLSRQN TPEQVHFYIF
     DFGTSALYSL KNLPHTADFI TSDQEEKLTK FMDLMKREIQ SRKRLFNRHN VNSKEMYQAV
     TGETLPQIII VVDNYEGYKD IQTEQLRNNF DIFIQTLARD GNSLGITVIV SGGRLAAIRP
     VLLANFKTRL SLKLTDESEI KTIMGNYTIS TESIAGRGLI TIEEVEVFQA ALSHRGVTPV
     QRLQALRQEI SQMDQFWQGN RPAKIPIVPE EISLEQFMDR ADTKNAIAKP ALPLGLDVTA
     VETIALDFST FRHLVVFSNN SEQVRLMVDR LIATVSQSSW NITALVLDVN GDYQNYETTV
     SHYVNDPALL SDMTDFMVSE IKNRETDGWD HYGIAFIPDL ESYEKVSGLS QTELVTLMTR
     GPRVGFFIIV GTTYSYLVSI NPVPKYLKEN GQYHFIGMKL NDQNFLDKAY DSKERQPAMD
     EAYIHNRKTY YKLKLSRNLT EETF
//