ID G5JP90_STRCG Unreviewed; 511 AA.
AC G5JP90;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 24-JAN-2024, entry version 29.
DE RecName: Full=Citrate lyase alpha chain {ECO:0000256|PIRNR:PIRNR009451};
DE Short=Citrase alpha chain {ECO:0000256|PIRNR:PIRNR009451};
DE EC=2.8.3.10 {ECO:0000256|PIRNR:PIRNR009451};
DE EC=4.1.3.6 {ECO:0000256|PIRNR:PIRNR009451};
DE AltName: Full=Citrate (pro-3S)-lyase alpha chain {ECO:0000256|PIRNR:PIRNR009451};
DE AltName: Full=Citrate CoA-transferase subunit {ECO:0000256|PIRNR:PIRNR009451};
GN Name=citF {ECO:0000313|EMBL:EHI73650.1};
GN ORFNames=STRCR_0324 {ECO:0000313|EMBL:EHI73650.1};
OS Streptococcus criceti HS-6.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC Streptococcus.
OX NCBI_TaxID=873449 {ECO:0000313|EMBL:EHI73650.1, ECO:0000313|Proteomes:UP000004322};
RN [1] {ECO:0000313|EMBL:EHI73650.1, ECO:0000313|Proteomes:UP000004322}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HS-6 {ECO:0000313|EMBL:EHI73650.1,
RC ECO:0000313|Proteomes:UP000004322};
RA Stanhope M.J., Durkin A.S., Hostetler J., Kim M., Radune D., Singh I.,
RA Town C.D.;
RL Submitted (JUL-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=acetyl-CoA + citrate = (3S)-citryl-CoA + acetate;
CC Xref=Rhea:RHEA:19405, ChEBI:CHEBI:16947, ChEBI:CHEBI:30089,
CC ChEBI:CHEBI:57288, ChEBI:CHEBI:57321; EC=2.8.3.10;
CC Evidence={ECO:0000256|PIRNR:PIRNR009451};
CC -!- CATALYTIC ACTIVITY:
CC Reaction=citrate = acetate + oxaloacetate; Xref=Rhea:RHEA:10760,
CC ChEBI:CHEBI:16452, ChEBI:CHEBI:16947, ChEBI:CHEBI:30089; EC=4.1.3.6;
CC Evidence={ECO:0000256|PIRNR:PIRNR009451};
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|PIRNR:PIRNR009451}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EHI73650.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AEUV02000002; EHI73650.1; -; Genomic_DNA.
DR RefSeq; WP_004225894.1; NZ_AEUV02000002.1.
DR AlphaFoldDB; G5JP90; -.
DR STRING; 873449.STRCR_0324; -.
DR eggNOG; COG3051; Bacteria.
DR OrthoDB; 9767643at2; -.
DR Proteomes; UP000004322; Unassembled WGS sequence.
DR GO; GO:0009346; C:ATP-independent citrate lyase complex; IEA:UniProtKB-UniRule.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0008815; F:citrate (pro-3S)-lyase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0008814; F:citrate CoA-transferase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006084; P:acetyl-CoA metabolic process; IEA:UniProtKB-UniRule.
DR Gene3D; 3.40.1080.10; Glutaconate Coenzyme A-transferase; 2.
DR InterPro; IPR006472; Citrate_lyase_asu.
DR InterPro; IPR037171; NagB/RpiA_transferase-like.
DR NCBIfam; TIGR01584; citF; 1.
DR PANTHER; PTHR40596; CITRATE LYASE ALPHA CHAIN; 1.
DR PANTHER; PTHR40596:SF1; CITRATE LYASE ALPHA CHAIN; 1.
DR Pfam; PF04223; CitF; 1.
DR PIRSF; PIRSF009451; Citrt_lyas_alpha; 1.
DR SUPFAM; SSF100950; NagB/RpiA/CoA transferase-like; 2.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|PIRNR:PIRNR009451};
KW Lyase {ECO:0000256|PIRNR:PIRNR009451, ECO:0000313|EMBL:EHI73650.1};
KW Transferase {ECO:0000256|PIRNR:PIRNR009451, ECO:0000313|EMBL:EHI73650.1}.
SQ SEQUENCE 511 AA; 55144 MW; 1C4D6612AFD2B055 CRC64;
MVENKLGRDI PQEYAERYGV FEGELAHIKD YQESSRRVKP VKPADDKLLS SIREAIEKTG
LKDGMTISFH HHFREGDYVM NMVLDEIAKM GIKDISIAPS SIANVHAPLI DHIKNGVVTN
ITSSGLRDKV GAAISEGIME NPVVIRSHGG RARAIAADDI HIDVAFLGAP SSDAYGNANG
TKGKATCGSL GYAMIDAKYA DQVVIITDTL VPYPNTPISI PQTDVDYVVV VDAIGDPEGI
AKGATRYTKN PKELLIAEYA AKVITGSPYY KEGFSFQTGT GGASLAVTRF MREQMLKDGI
KANFALGGIT NAMVELLEEG LVDKIMDVQD FDHPSAVSLD SNAEKHYEID ANMYASPLSK
GSVINQLDTC VLSALEVDTD FNVNVMTGSD GVIRGASGGH CDTAFAAKMS LVISPLVRGR
IPTFVDKVNT VITPGTSVDV IVTEVGIAIN PNRPDLIEHF KDLKVPQFTI EELKEKAYAI
VGNPDPIQYG DKVVALIEYR DGSLIDVVRN V
//
