ID G5JRA2_STRCG Unreviewed; 272 AA.
AC G5JRA2;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 24-JAN-2024, entry version 43.
DE RecName: Full=Pur operon repressor {ECO:0000256|ARBA:ARBA00018449};
GN ORFNames=STRCR_0689 {ECO:0000313|EMBL:EHI73843.1};
OS Streptococcus criceti HS-6.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC Streptococcus.
OX NCBI_TaxID=873449 {ECO:0000313|EMBL:EHI73843.1, ECO:0000313|Proteomes:UP000004322};
RN [1] {ECO:0000313|EMBL:EHI73843.1, ECO:0000313|Proteomes:UP000004322}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HS-6 {ECO:0000313|EMBL:EHI73843.1,
RC ECO:0000313|Proteomes:UP000004322};
RA Stanhope M.J., Durkin A.S., Hostetler J., Kim M., Radune D., Singh I.,
RA Town C.D.;
RL Submitted (JUL-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the purine/pyrimidine phosphoribosyltransferase
CC family. {ECO:0000256|ARBA:ARBA00008391}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EHI73843.1}.
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DR EMBL; AEUV02000002; EHI73843.1; -; Genomic_DNA.
DR RefSeq; WP_004226317.1; NZ_AEUV02000002.1.
DR AlphaFoldDB; G5JRA2; -.
DR STRING; 873449.STRCR_0689; -.
DR eggNOG; COG0503; Bacteria.
DR OrthoDB; 4213751at2; -.
DR Proteomes; UP000004322; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0045892; P:negative regulation of DNA-templated transcription; IEA:InterPro.
DR GO; GO:0045982; P:negative regulation of purine nucleobase metabolic process; IEA:InterPro.
DR CDD; cd06223; PRTases_typeI; 1.
DR Gene3D; 3.40.50.2020; -; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR000836; PRibTrfase_dom.
DR InterPro; IPR029057; PRTase-like.
DR InterPro; IPR015265; PuR_N.
DR InterPro; IPR010078; PurR_Bsub.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR NCBIfam; TIGR01743; purR_Bsub; 1.
DR PANTHER; PTHR43864; HYPOXANTHINE/GUANINE PHOSPHORIBOSYLTRANSFERASE; 1.
DR PANTHER; PTHR43864:SF2; PUR OPERON REPRESSOR; 1.
DR Pfam; PF00156; Pribosyltran; 1.
DR Pfam; PF09182; PuR_N; 1.
DR SUPFAM; SSF53271; PRTase-like; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Repressor {ECO:0000256|ARBA:ARBA00022491}.
FT DOMAIN 4..73
FT /note="Bacterial purine repressor N-terminal"
FT /evidence="ECO:0000259|Pfam:PF09182"
FT DOMAIN 107..264
FT /note="Phosphoribosyltransferase"
FT /evidence="ECO:0000259|Pfam:PF00156"
SQ SEQUENCE 272 AA; 29717 MW; 17D0B84F85D4081A CRC64;
MKLRRSERMV VISNYLINNP YSLTSLNTFA EKYEAAKSSI SEDIAIIKRA FENSHIGHIE
TVTGASGGVI FTPSISQEEA KAIVVDLCRR LSESDRILPG GYIYLSDLLS TPSILQSVGR
IIASAFAGQK IDAVMTVATK GVPLANAVAN VLNVPFVIVR RDLKITEGST VSVNYASGSS
DRIEKMFLSK RSLQPNSRVL IVDDFLKGGG TISGMISLLK EFESELVGVA VFAENAQKER
AHLFDYKSLL TVSEIDIKNN LVKVELGNIF KR
//
