ID   G5K0X5_9STRE            Unreviewed;       342 AA.
AC   G5K0X5;
DT   25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT   25-JAN-2012, sequence version 1.
DT   24-JAN-2024, entry version 38.
DE   SubName: Full=Integrase core domain protein {ECO:0000313|EMBL:EHI70358.1};
GN   ORFNames=STRIC_0251 {ECO:0000313|EMBL:EHI70358.1};
OS   Streptococcus ictaluri 707-05.
OC   Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC   Streptococcus.
OX   NCBI_TaxID=764299 {ECO:0000313|EMBL:EHI70358.1, ECO:0000313|Proteomes:UP000003330};
RN   [1] {ECO:0000313|EMBL:EHI70358.1, ECO:0000313|Proteomes:UP000003330}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=707-05 {ECO:0000313|EMBL:EHI70358.1,
RC   ECO:0000313|Proteomes:UP000003330};
RX   PubMed=24625962; DOI=10.1093/gbe/evu048;
RA   Richards V.P., Palmer S.R., Pavinski Bitar P.D., Qin X., Weinstock G.M.,
RA   Highlander S.K., Town C.D., Burne R.A., Stanhope M.J.;
RT   "Phylogenomics and the dynamic genome evolution of the genus
RT   Streptococcus.";
RL   Genome Biol. Evol. 6:741-753(2014).
CC   -!- FUNCTION: Required for the transposition of the insertion element.
CC       {ECO:0000256|ARBA:ARBA00002190}.
CC   -!- SIMILARITY: Belongs to the transposase IS30 family.
CC       {ECO:0000256|ARBA:ARBA00006363}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EHI70358.1}.
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DR   EMBL; AEUX02000004; EHI70358.1; -; Genomic_DNA.
DR   AlphaFoldDB; G5K0X5; -.
DR   eggNOG; COG2826; Bacteria.
DR   OrthoDB; 2223608at2; -.
DR   Proteomes; UP000003330; Unassembled WGS sequence.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0004803; F:transposase activity; IEA:InterPro.
DR   GO; GO:0015074; P:DNA integration; IEA:InterPro.
DR   GO; GO:0006313; P:DNA transposition; IEA:InterPro.
DR   Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR   Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR   InterPro; IPR001584; Integrase_cat-core.
DR   InterPro; IPR025246; IS30-like_HTH.
DR   InterPro; IPR012337; RNaseH-like_sf.
DR   InterPro; IPR036397; RNaseH_sf.
DR   InterPro; IPR001598; Transposase_IS30_CS.
DR   NCBIfam; NF033563; transpos_IS30; 1.
DR   PANTHER; PTHR10948; TRANSPOSASE; 1.
DR   PANTHER; PTHR10948:SF23; TRANSPOSASE INSI FOR INSERTION SEQUENCE ELEMENT IS30A-RELATED; 1.
DR   Pfam; PF13936; HTH_38; 1.
DR   Pfam; PF00665; rve; 1.
DR   SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR   PROSITE; PS50994; INTEGRASE; 1.
DR   PROSITE; PS01043; TRANSPOSASE_IS30; 1.
PE   3: Inferred from homology;
KW   DNA recombination {ECO:0000256|ARBA:ARBA00023172};
KW   Reference proteome {ECO:0000313|Proteomes:UP000003330}.
FT   DOMAIN          182..341
FT                   /note="Integrase catalytic"
FT                   /evidence="ECO:0000259|PROSITE:PS50994"
SQ   SEQUENCE   342 AA;  39154 MW;  A645E953CF029AEA CRC64;
     MNMSNINSTR KSSYSHLSAT ERGEIAAYLK MGKKPAEIAR LLGRHRSTIC REIKRGSVEQ
     VKDKNGKQTF FNAYFADSGQ RVYETNRQKS SYLKLNNCSA RFIEQLESAL TANIRLHSVD
     SFVQTYKVNH PEEVVPSTKT IYRYIKEGVL AIKPIDLPKM VSIRKRSKKV MKTNKKTLGK
     SIEERPEYIN DRSEFGHWEI DLVLGKKTKG EAVMLTLVER QTRYALGVKL EDKQSQTINR
     AVTHLISQYP IASITADNGS EFSLLSNLEA VEVYFAHPYS SHERGKNENF NGLLREYVPK
     GVSLNPLTSE ELDNYITAIN ERPRRLLQYQ SSKFLFELSR TA
//