ID G5KG40_9STRE Unreviewed; 1634 AA.
AC G5KG40;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 24-JAN-2024, entry version 46.
DE SubName: Full=Putative cross-wall-targeting lipoprotein signal {ECO:0000313|EMBL:EHJ57080.1};
GN ORFNames=STRUR_1201 {ECO:0000313|EMBL:EHJ57080.1};
OS Streptococcus urinalis 2285-97.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC Streptococcus.
OX NCBI_TaxID=764291 {ECO:0000313|EMBL:EHJ57080.1, ECO:0000313|Proteomes:UP000005388};
RN [1] {ECO:0000313|EMBL:EHJ57080.1, ECO:0000313|Proteomes:UP000005388}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=2285-97 {ECO:0000313|EMBL:EHJ57080.1};
RX PubMed=24625962; DOI=10.1093/gbe/evu048;
RA Richards V.P., Palmer S.R., Pavinski Bitar P.D., Qin X., Weinstock G.M.,
RA Highlander S.K., Town C.D., Burne R.A., Stanhope M.J.;
RT "Phylogenomics and the dynamic genome evolution of the genus
RT Streptococcus.";
RL Genome Biol. Evol. 6:741-753(2014).
CC -!- SIMILARITY: Belongs to the antigen I/II family.
CC {ECO:0000256|ARBA:ARBA00024351}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EHJ57080.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AEUZ02000001; EHJ57080.1; -; Genomic_DNA.
DR RefSeq; WP_006739811.1; NZ_AEUZ02000001.1.
DR STRING; 764291.STRUR_1201; -.
DR eggNOG; COG3064; Bacteria.
DR eggNOG; COG3087; Bacteria.
DR Proteomes; UP000005388; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 2.60.40.740; -; 5.
DR Gene3D; 2.60.530.10; Major cell-surface adhesin PAc; 1.
DR InterPro; IPR026345; Adh_isopep-form_adh_dom.
DR InterPro; IPR041324; AgI/II_N.
DR InterPro; IPR032300; Antigen_C.
DR InterPro; IPR021197; Cross-wall-target_lipo_motif.
DR InterPro; IPR013574; Glucan-bd_C/Surface_Ag-I/II_V.
DR InterPro; IPR019931; LPXTG_anchor.
DR InterPro; IPR036234; SA_I/II_PAC_V_sf.
DR NCBIfam; TIGR04228; isopep_sspB_C2; 3.
DR NCBIfam; TIGR01167; LPXTG_anchor; 1.
DR NCBIfam; TIGR03726; strep_RK_lipo; 1.
DR Pfam; PF18652; Adhesin_P1_N; 1.
DR Pfam; PF17998; AgI_II_C2; 3.
DR Pfam; PF16364; Antigen_C; 1.
DR Pfam; PF08363; GbpC; 2.
DR Pfam; PF00746; Gram_pos_anchor; 1.
DR SUPFAM; SSF74914; V-region of surface antigen I/II (SA I/II, PAC); 1.
DR PROSITE; PS50847; GRAM_POS_ANCHORING; 1.
PE 3: Inferred from homology;
KW Cell wall {ECO:0000256|ARBA:ARBA00022512};
KW Lipoprotein {ECO:0000313|EMBL:EHJ57080.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Peptidoglycan-anchor {ECO:0000256|ARBA:ARBA00023088};
KW Reference proteome {ECO:0000313|Proteomes:UP000005388};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 27..47
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1601..1634
FT /note="Gram-positive cocci surface proteins LPxTG"
FT /evidence="ECO:0000259|PROSITE:PS50847"
FT REGION 69..96
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 125..147
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1564..1603
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 125..141
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1572..1597
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1634 AA; 179102 MW; CE288E3810DA5D19 CRC64;
MTKQCHHHFL VNQEKAEKHV FRKSKKYRTL CSVALVTMVT AVVAWGGQVA QADEVVTSSQ
GKTVQLTENP ATNLPEAQPT PVAEQTNSLA STGQSDGAIT VTVPHDVVTQ AVNQATAEGV
TTVQDQPMDL GNTTSASETS KQLDKAEADA ARQAEAITQL TNTYKADKAT YEQDKTRVEQ
GNAALAASHK DATQAGKALN HSVDSTVSKI KDQDQSANVT VTTQTVTSGD GSTVSGYQDY
TSAVAAIDKQ NKDNLSEYES KKKDADAIVA KNLLIQKANE DGVAKAKADT EAIDKRNQAG
QKAVDDENKA GQAAVDAYNK DQQKLVTDRE AEIAAITKSN KEKEEAAKKE NAAIDAYNTK
EMERYKRDLA EISKGEEGYI SQALAQALNL NNGEPQARHS ADTRNPNRIV AKGDAMLGGY
SKILDSTGFF VYDTFKTGET LSFTYQNLQN ARFDGKKITK VAYDITNLVS PTGTNAVQLV
VPNDPTEGFI AYRNDGTGNW RTDKMEFRVK AKYFLEDGSQ VSFTKEKPGV FTHSSLNHND
IGLEYVKDSS GKFVPINGST IQVTNEGLAR SLGSNRASDL KLPEEWDTSY SNYAYKGAIV
STVTSGNTYT VTFGQGDMPQ NVGLSYWFAL NTLPVARTVK PYSPKPHVTP KLEPIPEPIK
VVPKTFTPKT FTPEPPVSFK EKPLEKVTQP SLTLTKVTLP KDPTPEPLPK APQVPTIHYH
DYRLTTTPEI VKEVINTDQV NLHDKTVAKD STVIYPLTVD AFSPNRAKTT SLTFEDYLPA
GYAFDKEKTQ AENGNYTLTF DAAKNFVTLT AKEALLQEVN QDLTKSYQLE APKLYGSLQN
DGATYSNSYK LLINKGTPNA YTVTSNVVTV RTPGDGTTTS RIEPQKKNEN EDGVVINDTV
VALGTTNHYR LTWDLDQYKG DRSSKETIAR GFFFVDDYPE EVLNLVDQGT SITTPEGKDV
SGITVKAYAS LSEAPKDLQD KLAHAKISPK GAFQVFMPND NQAFYDQYVI TGTSLNLVTK
MTVKDSLYGQ TKTYRNKAYQ VDFGNGYETD EVTNTLVSPT PKKQNLNKGK VDINGKPMVV
GSQNHYTLSW DLDQYRGIKA DKAQIAQGFY FVDDYPEEAL LPDETSIQLV TIDGKAVSGV
TVKTYTSLSE APKPLQAALS KRKIVPKGAF QVFMAEDPQA FYDSYVTQGQ NITIITPMTV
RESMLNSGKS YDNVAYQVDF GQAYETNTVT NHVPKVTPHK TNTNKEGVSI DGKTVLPNTV
NYYKIVLDYS QYKDLVVTED VLAKGFYMVD DYPEEALSLN ADGIQVMDKA GNLVKGISVK
AYASLSEAPK VVQDAMAKRQ FTPKGAILVL SADDPKAFYE AYVKTGQTLV VTLPMTIKNE
LTKTGGKYEN TAYQIDFGLA YVTETVVNNV PKLDPQKDVV IDLPQKENSL DGKEVALNQV
FNYRLVGALI PGNRATPLIE YRFDDDYDES HDDYNGVYKA YTLVDVTLKD GMVLPKGTEV
TKYTLQHVDT SKGTVTISFD QEFLEKLAEE SEFQADVYVQ MKRIASGEVE NTVLHTVNGY
TISSNTVKTT TPEPEPPTPT QPTPPQPPIP TQEPPVPASV LPNTGESQSL LALVGGGLLL
GLAYGLSKRK MEDN
//
