ID G5KHH6_9STRE Unreviewed; 597 AA.
AC G5KHH6;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE SubName: Full=Oligoendopeptidase F {ECO:0000313|EMBL:EHJ55770.1};
DE EC=3.4.24.- {ECO:0000313|EMBL:EHJ55770.1};
GN Name=pepF_2 {ECO:0000313|EMBL:EHJ55770.1};
GN ORFNames=STRUR_1491 {ECO:0000313|EMBL:EHJ55770.1};
OS Streptococcus urinalis 2285-97.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC Streptococcus.
OX NCBI_TaxID=764291 {ECO:0000313|EMBL:EHJ55770.1, ECO:0000313|Proteomes:UP000005388};
RN [1] {ECO:0000313|EMBL:EHJ55770.1, ECO:0000313|Proteomes:UP000005388}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=2285-97 {ECO:0000313|EMBL:EHJ55770.1};
RX PubMed=24625962; DOI=10.1093/gbe/evu048;
RA Richards V.P., Palmer S.R., Pavinski Bitar P.D., Qin X., Weinstock G.M.,
RA Highlander S.K., Town C.D., Burne R.A., Stanhope M.J.;
RT "Phylogenomics and the dynamic genome evolution of the genus
RT Streptococcus.";
RL Genome Biol. Evol. 6:741-753(2014).
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EHJ55770.1}.
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DR EMBL; AEUZ02000001; EHJ55770.1; -; Genomic_DNA.
DR RefSeq; WP_006738559.1; NZ_AEUZ02000001.1.
DR AlphaFoldDB; G5KHH6; -.
DR STRING; 764291.STRUR_1491; -.
DR eggNOG; COG1164; Bacteria.
DR Proteomes; UP000005388; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd09609; M3B_PepF; 1.
DR Gene3D; 1.10.1370.20; Oligoendopeptidase f, C-terminal domain; 1.
DR Gene3D; 1.20.140.70; Oligopeptidase f, N-terminal domain; 1.
DR InterPro; IPR034009; M3B_PepF_4.
DR InterPro; IPR042088; OligoPept_F_C.
DR InterPro; IPR045090; Pept_M3A_M3B.
DR InterPro; IPR001567; Pept_M3A_M3B_dom.
DR InterPro; IPR004438; Peptidase_M3B.
DR NCBIfam; TIGR00181; pepF; 1.
DR PANTHER; PTHR11804; PROTEASE M3 THIMET OLIGOPEPTIDASE-RELATED; 1.
DR PANTHER; PTHR11804:SF45; SIMILAR TO OLIGOENDOPEPTIDASE; 1.
DR Pfam; PF01432; Peptidase_M3; 1.
DR SUPFAM; SSF55486; Metalloproteases ('zincins'), catalytic domain; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:EHJ55770.1};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Metalloprotease {ECO:0000256|ARBA:ARBA00023049};
KW Protease {ECO:0000256|ARBA:ARBA00022670};
KW Reference proteome {ECO:0000313|Proteomes:UP000005388};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT DOMAIN 199..579
FT /note="Peptidase M3A/M3B catalytic"
FT /evidence="ECO:0000259|Pfam:PF01432"
SQ SEQUENCE 597 AA; 69042 MW; 3CC7E69C09E704F1 CRC64;
MKLKKRSEFP ETELWDLTAL YKDRNDFLLA IEKALEDVNS FKRNYKNHLN TKKDFEMALF
EIEQIYIQIS HIETYSFMPQ TTDFSSDEFA QIAKAGDDFV TKASVELSFF DTALANADTD
ILDALEKNDY FKAIIRQAKI QKAHLLTPEV EETITNFREI LNAPYDIYTK MRAGDFEMEN
FTVNGKQYEN SFVSYENFYQ NHEDADVREK AFRSFSKGLR KHQNTAAAAY LSKVKSEKLI
ADMKGYASVF DYLLAEQEVD KSMFDRQIDL IMTKFGPVAQ KFVKHVAQVN GLEKMTFADW
KLDIDNELNP EVTIDDAYKL VMDSLKPLGQ EYLTEIERYQ TERWVDFAAN ENKDSGGYAA
DPYKVHPYVL MSWTGRMSDV YTLIHEIGHS GQFIFSDNAQ SYFNTHMSTY YVEAPSTFNE
LMLSDYLENQ FDQPRQKRFA LAHRLTDTYF HNFITHLLEA AFQRKVYNLI EDGGTFGAEQ
LNHIMKDVLT EFWGDAIEID DDAALTWMRQ SHYYMGLYSY TYSAGLVIST TGYLHLKSHP
NGAKDWLAFL KSGGSRTPIE TAKLIGADIS TDKPILDTID FLDKTVEQII TYTNEIN
//
