ID G5KI48_9STRE Unreviewed; 247 AA.
AC G5KI48;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 24-JAN-2024, entry version 42.
DE RecName: Full=Tyrosine recombinase XerD-like {ECO:0000256|HAMAP-Rule:MF_01817};
GN Name=xerD {ECO:0000313|EMBL:EHJ57146.1};
GN ORFNames=STRUR_0330 {ECO:0000313|EMBL:EHJ57146.1};
OS Streptococcus urinalis 2285-97.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC Streptococcus.
OX NCBI_TaxID=764291 {ECO:0000313|EMBL:EHJ57146.1, ECO:0000313|Proteomes:UP000005388};
RN [1] {ECO:0000313|EMBL:EHJ57146.1, ECO:0000313|Proteomes:UP000005388}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=2285-97 {ECO:0000313|EMBL:EHJ57146.1};
RX PubMed=24625962; DOI=10.1093/gbe/evu048;
RA Richards V.P., Palmer S.R., Pavinski Bitar P.D., Qin X., Weinstock G.M.,
RA Highlander S.K., Town C.D., Burne R.A., Stanhope M.J.;
RT "Phylogenomics and the dynamic genome evolution of the genus
RT Streptococcus.";
RL Genome Biol. Evol. 6:741-753(2014).
CC -!- FUNCTION: Putative tyrosine recombinase. Not involved in the cutting
CC and rejoining of the recombining DNA molecules on dif(SL) site.
CC {ECO:0000256|HAMAP-Rule:MF_01817}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_01817}.
CC -!- SIMILARITY: Belongs to the 'phage' integrase family. XerD-like
CC subfamily. {ECO:0000256|HAMAP-Rule:MF_01817}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EHJ57146.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AEUZ02000001; EHJ57146.1; -; Genomic_DNA.
DR RefSeq; WP_006739870.1; NZ_AEUZ02000001.1.
DR AlphaFoldDB; G5KI48; -.
DR STRING; 764291.STRUR_0330; -.
DR eggNOG; COG0582; Bacteria.
DR Proteomes; UP000005388; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0009037; F:tyrosine-based site-specific recombinase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006313; P:DNA transposition; IEA:UniProtKB-UniRule.
DR Gene3D; 1.10.443.10; Intergrase catalytic core; 1.
DR HAMAP; MF_01817; Recomb_XerD_like; 1.
DR InterPro; IPR044068; CB.
DR InterPro; IPR011010; DNA_brk_join_enz.
DR InterPro; IPR013762; Integrase-like_cat_sf.
DR InterPro; IPR002104; Integrase_catalytic.
DR InterPro; IPR020876; Tyrosine_recombinase_XerD-like.
DR Pfam; PF00589; Phage_integrase; 1.
DR SUPFAM; SSF56349; DNA breaking-rejoining enzymes; 1.
DR PROSITE; PS51900; CB; 1.
DR PROSITE; PS51898; TYR_RECOMBINASE; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|HAMAP-Rule:MF_01817};
KW DNA integration {ECO:0000256|HAMAP-Rule:MF_01817};
KW DNA recombination {ECO:0000256|ARBA:ARBA00023172, ECO:0000256|HAMAP-
KW Rule:MF_01817};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|HAMAP-
KW Rule:MF_01817}; Reference proteome {ECO:0000313|Proteomes:UP000005388}.
FT DOMAIN 1..72
FT /note="Core-binding (CB)"
FT /evidence="ECO:0000259|PROSITE:PS51900"
FT DOMAIN 84..247
FT /note="Tyr recombinase"
FT /evidence="ECO:0000259|PROSITE:PS51898"
FT ACT_SITE 244
FT /note="O-(3'-phospho-DNA)-tyrosine intermediate"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01817"
SQ SEQUENCE 247 AA; 29695 MW; F34F03F4D9AAD9D7 CRC64;
MKQYIKPFID SKDLSINSQK SYYYDLNQFI EVIHNRLTKE RLAIYEQSIK DLTISAKKRK
QSAVNQFLLF LYEHNITETF FRLKSKEKLT KSPIKNELIN DQLFFKNVKE QKGQLIALFI
LEVGLLPNEI QLLKWADIDL DYHIISLKNE NQMRIIDFSQ SLVSYMTDVL NRETVYLFEK
NHHYFSRQWH YNRLKSFLNE IGLPYLNAQL LREQYILRQI DKGKTIEEVR ESLGLKSQVT
LEKYFKH
//
