ID   G5ZWL4_9PROT            Unreviewed;       469 AA.
AC   G5ZWL4;
DT   25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT   25-JAN-2012, sequence version 1.
DT   24-JAN-2024, entry version 34.
DE   SubName: Full=NAD-dependent aldehyde dehydrogenase {ECO:0000313|EMBL:EHI49447.1};
GN   ORFNames=HIMB100_00004080 {ECO:0000313|EMBL:EHI49447.1};
OS   SAR116 cluster alpha proteobacterium HIMB100.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; SAR116 cluster.
OX   NCBI_TaxID=909943 {ECO:0000313|EMBL:EHI49447.1, ECO:0000313|Proteomes:UP000004261};
RN   [1] {ECO:0000313|EMBL:EHI49447.1, ECO:0000313|Proteomes:UP000004261}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=strain HIMB100 {ECO:0000313|Proteomes:UP000004261};
RX   PubMed=22675578; DOI=10.4056/sigs.1854551;
RA   Grote J., Bayindirli C., Bergauer K., Carpintero de Moraes P., Chen H.,
RA   D'Ambrosio L., Edwards B., Fernandez-Gomez B., Hamisi M., Logares R.,
RA   Nguyen D., Rii Y.M., Saeck E., Schutte C., Widner B., Church M.J.,
RA   Steward G.F., Karl D.M., Delong E.F., Eppley J.M., Schuster S.C.,
RA   Kyrpides N.C., Rappe M.S.;
RT   "Draft genome sequence of strain HIMB100, a cultured representative of the
RT   SAR116 clade of marine Alphaproteobacteria.";
RL   Stand. Genomic Sci. 5:269-278(2011).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EHI49447.1}.
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DR   EMBL; AFXB01000004; EHI49447.1; -; Genomic_DNA.
DR   AlphaFoldDB; G5ZWL4; -.
DR   STRING; 909943.HIMB100_00004080; -.
DR   PATRIC; fig|909943.3.peg.417; -.
DR   eggNOG; COG1012; Bacteria.
DR   OrthoDB; 9815791at2; -.
DR   Proteomes; UP000004261; Unassembled WGS sequence.
DR   GO; GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR   InterPro; IPR016161; Ald_DH/histidinol_DH.
DR   InterPro; IPR016163; Ald_DH_C.
DR   InterPro; IPR016162; Ald_DH_N.
DR   InterPro; IPR015590; Aldehyde_DH_dom.
DR   PANTHER; PTHR11699:SF68; ACETALDEHYDE DEHYDROGENASE (ACETYLATING) EUTE; 1.
DR   PANTHER; PTHR11699; ALDEHYDE DEHYDROGENASE-RELATED; 1.
DR   Pfam; PF00171; Aldedh; 1.
DR   SUPFAM; SSF53720; ALDH-like; 1.
PE   4: Predicted;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000004261}.
FT   DOMAIN          7..272
FT                   /note="Aldehyde dehydrogenase"
FT                   /evidence="ECO:0000259|Pfam:PF00171"
SQ   SEQUENCE   469 AA;  50197 MW;  E48BDDC6893EF138 CRC64;
     MTGADDTTCI DELVAAARAA QHYYEENGSQ DLFDKACQAV AWVLMEPTRN DQLATMAVAE
     TGLGNVADKI RKNHNKTLGL MRDLKDVKSF GHIGDDHAKG LSTYLRPKGV IAAIVPSTNP
     LATPVNNIIN ALKTGNAIII APSPKGVKPA TVLLGYIHDA LAKLGLPAEL VQMVPAPPSK
     PKTQRLMQLA DLVVVTGSQS NVRAGYMSGT PAIGVGAGNV VTIIDETADL RAAAAKIAAS
     KSFDNATSCS SENAVVVVDA VYDEMLAALA EEGGFLLTDA QSQTVQDIHW QNGKMTTTLL
     AQDIDKVLAA TGLDKVAPAN TRFLLLPQTD IGPQNPLTGE KMARFLALHR AQDFDEAVEK
     AITIQNYQGA GHSLGLHSSD DSRAHHLARH ARTCRVIVNQ AHCFATGGFF NNGMPFSLSM
     GCGSWGGNSI DENLNWTHFV NHVNVVRVIP EDKPELEDIF ADYWDEFGK
//