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Database: UniProt
Entry: G6FRK5_9CYAN
LinkDB: G6FRK5_9CYAN
Original site: G6FRK5_9CYAN 
ID   G6FRK5_9CYAN            Unreviewed;       288 AA.
AC   G6FRK5;
DT   25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT   25-JAN-2012, sequence version 1.
DT   13-FEB-2019, entry version 30.
DE   RecName: Full=Prephenate dehydratase {ECO:0000256|RuleBase:RU361254};
DE            Short=PDT {ECO:0000256|RuleBase:RU361254};
DE            EC=4.2.1.51 {ECO:0000256|RuleBase:RU361254};
GN   Name=pheA {ECO:0000256|RuleBase:RU361254};
GN   ORFNames=FJSC11DRAFT_1502 {ECO:0000313|EMBL:EHC16079.1};
OS   Fischerella thermalis.
OC   Bacteria; Cyanobacteria; Nostocales; Hapalosiphonaceae; Fischerella.
OX   NCBI_TaxID=372787 {ECO:0000313|EMBL:EHC16079.1, ECO:0000313|Proteomes:UP000004344};
RN   [1] {ECO:0000313|EMBL:EHC16079.1, ECO:0000313|Proteomes:UP000004344}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JSC-11 {ECO:0000313|EMBL:EHC16079.1,
RC   ECO:0000313|Proteomes:UP000004344};
RG   US DOE Joint Genome Institute (JGI-PGF);
RA   Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA   Peters L., Land M.L., Hauser L., Sarkisova S., Bryant D.A., Brown I.,
RA   Woyke T.J.;
RT   "The draft genome of Fischerella sp. JSC-11.";
RL   Submitted (SEP-2011) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=H(+) + prephenate = 3-phenylpyruvate + CO2 + H2O;
CC         Xref=Rhea:RHEA:21648, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:16526, ChEBI:CHEBI:18005, ChEBI:CHEBI:29934;
CC         EC=4.2.1.51; Evidence={ECO:0000256|RuleBase:RU361254};
CC   -!- PATHWAY: Amino-acid biosynthesis; L-phenylalanine biosynthesis;
CC       phenylpyruvate from prephenate: step 1/1.
CC       {ECO:0000256|RuleBase:RU361254}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:EHC16079.1}.
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DR   EMBL; AGIZ01000004; EHC16079.1; -; Genomic_DNA.
DR   RefSeq; WP_009456048.1; NZ_AGIZ01000004.1.
DR   EnsemblBacteria; EHC16079; EHC16079; FJSC11DRAFT_1502.
DR   GeneID; 35799619; -.
DR   UniPathway; UPA00121; UER00345.
DR   Proteomes; UP000004344; Unassembled WGS sequence.
DR   GO; GO:0004106; F:chorismate mutase activity; IEA:InterPro.
DR   GO; GO:0004664; F:prephenate dehydratase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0009094; P:L-phenylalanine biosynthetic process; IEA:UniProtKB-UniPathway.
DR   InterPro; IPR002912; ACT_dom.
DR   InterPro; IPR008242; Chor_mutase/pphenate_deHydtase.
DR   InterPro; IPR001086; Preph_deHydtase.
DR   InterPro; IPR018528; Preph_deHydtase_CS.
DR   Pfam; PF01842; ACT; 1.
DR   Pfam; PF00800; PDT; 1.
DR   PIRSF; PIRSF001500; Chor_mut_pdt_Ppr; 1.
DR   PROSITE; PS51671; ACT; 1.
DR   PROSITE; PS00857; PREPHENATE_DEHYDR_1; 1.
DR   PROSITE; PS00858; PREPHENATE_DEHYDR_2; 1.
DR   PROSITE; PS51171; PREPHENATE_DEHYDR_3; 1.
PE   4: Predicted;
KW   Amino-acid biosynthesis {ECO:0000256|RuleBase:RU361254};
KW   Aromatic amino acid biosynthesis {ECO:0000256|RuleBase:RU361254};
KW   Complete proteome {ECO:0000313|Proteomes:UP000004344};
KW   Lyase {ECO:0000256|RuleBase:RU361254, ECO:0000313|EMBL:EHC16079.1};
KW   Phenylalanine biosynthesis {ECO:0000256|RuleBase:RU361254};
KW   Reference proteome {ECO:0000313|Proteomes:UP000004344}.
FT   DOMAIN        4    187       Prephenate dehydratase.
FT                                {ECO:0000259|PROSITE:PS51171}.
FT   DOMAIN      206    283       ACT. {ECO:0000259|PROSITE:PS51671}.
FT   SITE        180    180       Essential for prephenate dehydratase
FT                                activity. {ECO:0000256|PIRSR:PIRSR001500-
FT                                2}.
SQ   SEQUENCE   288 AA;  31558 MW;  FA6E9534473D28B2 CRC64;
     MTLSIAHLGP PGTYAEQAAL LYVNWLSKNQ GLKAILCPYP SIAQTLRAVA QSQVHQAVVP
     VENSIEGSVT MTMDTLWQLD NLQIQLALVI PIVHTLISCA HSLESIKTVY SHPQALAQCQ
     KWLEEFLPSV QIIPANSTTE ALQTLQQDLT AAAISSERAA QLYNLPVLVN GINDYPENCT
     RFWVVSQGDM PNSYQKSSLK ISHTSLAFSV GANVPGALVK PLQVFAELGI NLSRIESRPT
     KRSLGEYLFF IDAEADTSQL QMQSALQELT QYTEILKIFG SYGVLPMG
//
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