ID   G7CBE8_MYCT3            Unreviewed;      1137 AA.
AC   G7CBE8;
DT   25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT   25-JAN-2012, sequence version 1.
DT   27-MAR-2024, entry version 39.
DE   SubName: Full=RecB family-like nuclease {ECO:0000313|EMBL:EHI14673.1};
GN   ORFNames=KEK_01450 {ECO:0000313|EMBL:EHI14673.1};
OS   Mycolicibacterium thermoresistibile (strain ATCC 19527 / DSM 44167 / CIP
OS   105390 / JCM 6362 / NCTC 10409 / 316) (Mycobacterium thermoresistibile).
OC   Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC   Mycolicibacterium.
OX   NCBI_TaxID=1078020 {ECO:0000313|EMBL:EHI14673.1, ECO:0000313|Proteomes:UP000004915};
RN   [1] {ECO:0000313|EMBL:EHI14673.1, ECO:0000313|Proteomes:UP000004915}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 19527 / DSM 44167 / CIP 105390 / JCM 6362 / NCTC 10409 /
RC   316 {ECO:0000313|Proteomes:UP000004915};
RG   Tuberculosis Structural Genomics Consortium;
RA   Ioerger T.R.;
RL   Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EHI14673.1}.
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DR   EMBL; AGVE01000012; EHI14673.1; -; Genomic_DNA.
DR   RefSeq; WP_003923699.1; NZ_AGVE01000012.1.
DR   AlphaFoldDB; G7CBE8; -.
DR   PATRIC; fig|1078020.3.peg.280; -.
DR   eggNOG; COG1112; Bacteria.
DR   eggNOG; COG2251; Bacteria.
DR   Proteomes; UP000004915; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   CDD; cd17934; DEXXQc_Upf1-like; 1.
DR   CDD; cd18808; SF1_C_Upf1; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR041679; DNA2/NAM7-like_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR019993; RecB_nuclease_TM0106_put.
DR   InterPro; IPR012337; RNaseH-like_sf.
DR   InterPro; IPR047187; SF1_C_Upf1.
DR   InterPro; IPR038720; YprB_RNase_H-like_dom.
DR   NCBIfam; TIGR03491; TM0106 family RecB-like putative nuclease; 1.
DR   PANTHER; PTHR43788; DNA2/NAM7 HELICASE FAMILY MEMBER; 1.
DR   PANTHER; PTHR43788:SF6; RECBCD ENZYME SUBUNIT RECD; 1.
DR   Pfam; PF13087; AAA_12; 1.
DR   Pfam; PF13604; AAA_30; 1.
DR   Pfam; PF13482; RNase_H_2; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF53098; Ribonuclease H-like; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000004915}.
FT   DOMAIN          319..506
FT                   /note="YprB ribonuclease H-like"
FT                   /evidence="ECO:0000259|Pfam:PF13482"
FT   DOMAIN          938..1111
FT                   /note="DNA2/NAM7 helicase-like C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF13087"
SQ   SEQUENCE   1137 AA;  124415 MW;  33B9D1DBEAD1F8E8 CRC64;
     MFVAADRVIY SASDLAAAAR CEYALLRSFD AELGWGPPVA VDDGMLTRTV ELGDAHERRH
     LEALREASDD ADDPVTVIGR PAYTVEGLTA AAEATLRAVQ RRAPVIYQAT MFDGRFVGFA
     DFLVHEPADD GGRYRLRDTK LARSAKVEAL LQLAAYAEAL IAAGVPVAPE VELVLGDGHT
     VRYRVDELLP VYAPRRAALE RLLDEHLAGG RPVRWEDEEV RACFRCPECR SRVAESDDLL
     LVAGMRVSQR ARLLDAGITT RTALARHRGP VPGLPARTVD ALTEQARLQI EAGDTGKPPF
     VVADPQPLAL LPDPDKGDLF FDFEGDPLWT VDGREWGLEY LWGVLESGGR FTALWAHDRA
     EERRALADFL AFVRKRRRRY PNMHIYHYAA YEKTTLLRLA GRYGVGEDEV DELLRSGVLV
     DLFPLVRKSL RVGTENYSLK SLEPLYMGAE LRAGDVTTAA ESINMYARFT ELTAAGRHDE
     ARTVLKEIED YNHYDCRSTR KLRDWLLTLA FESGVPPLGP QPVVTDHTDD EEPDDVAAAL
     SAFAGDTVEQ RTAEQTAVAL LAAARGYHRR ERKPFWWAHF DRLNNPVDEW GDSSDVFLAD
     NAVVVEDWHK PPRARKLQRH TRLTGTLAAG ALGDRVFALY EPPAPRHLTN DPDRRAAGDA
     DVIAVDDPAV PTEVVICERV DDGGQFDQLP FALTPGQLIP TEPLRKSIDD TAAAVAAGLP
     ALPDTAVVDL LARRTPRTRS GAALPHTGDA IGDITAALLD LDSSFVAVHG PPGTGKTYTA
     ARVIARLVTE HRWRVGVVAQ SHAVVENLFG DLIGAGVAPE LIAKKKHAPD PAWREIDPAG
     YAAFLDDHDG CVIGGTAWDF AHPNRVPPER LDVLVIEEAG QFCLANTIAV ARAARNLLLL
     GDPQQLPQVS QGHHPEPVDC SALGWLVAEH RTLPERFGYF LDRSHRMHPA VCARVSRLAY
     ENRLHSAEER TAARRLAGHP PGVRVLTVEH LGNSTSSPEE ADAIVAEIGR LLGAEWTDEH
     GTRGLRPEDV LVVAPYNAQV VLLRRCLDEA GLSGVDVGTV DKFQGRQAPV VFISMTASSI
     DDVPRGISFL LNRNRLNVAV SRAQYASVVV RSAALTDYLP STPDGLVELG AFLTLTG
//