ID G7CBP8_MYCT3 Unreviewed; 304 AA.
AC G7CBP8;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE SubName: Full=Putative adenylate/guanylate cyclase {ECO:0000313|EMBL:EHI14552.1};
GN ORFNames=KEK_01960 {ECO:0000313|EMBL:EHI14552.1};
OS Mycolicibacterium thermoresistibile (strain ATCC 19527 / DSM 44167 / CIP
OS 105390 / JCM 6362 / NCTC 10409 / 316) (Mycobacterium thermoresistibile).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycolicibacterium.
OX NCBI_TaxID=1078020 {ECO:0000313|EMBL:EHI14552.1, ECO:0000313|Proteomes:UP000004915};
RN [1] {ECO:0000313|EMBL:EHI14552.1, ECO:0000313|Proteomes:UP000004915}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 19527 / DSM 44167 / CIP 105390 / JCM 6362 / NCTC 10409 /
RC 316 {ECO:0000313|Proteomes:UP000004915};
RG Tuberculosis Structural Genomics Consortium;
RA Ioerger T.R.;
RL Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EHI14552.1}.
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DR EMBL; AGVE01000014; EHI14552.1; -; Genomic_DNA.
DR AlphaFoldDB; G7CBP8; -.
DR PATRIC; fig|1078020.3.peg.381; -.
DR eggNOG; COG2114; Bacteria.
DR Proteomes; UP000004915; Unassembled WGS sequence.
DR GO; GO:0004016; F:adenylate cyclase activity; IEA:UniProt.
DR GO; GO:0009190; P:cyclic nucleotide biosynthetic process; IEA:InterPro.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR CDD; cd07302; CHD; 1.
DR Gene3D; 3.30.70.1230; Nucleotide cyclase; 1.
DR InterPro; IPR001054; A/G_cyclase.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR PANTHER; PTHR43081; ADENYLATE CYCLASE, TERMINAL-DIFFERENTIATION SPECIFIC-RELATED; 1.
DR PANTHER; PTHR43081:SF1; PH-SENSITIVE ADENYLATE CYCLASE RV1264; 1.
DR Pfam; PF00211; Guanylate_cyc; 1.
DR SMART; SM00044; CYCc; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR PROSITE; PS50125; GUANYLATE_CYCLASE_2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000004915}.
FT DOMAIN 117..229
FT /note="Guanylate cyclase"
FT /evidence="ECO:0000259|PROSITE:PS50125"
FT REGION 1..25
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 284..304
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..19
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 304 AA; 32294 MW; BEE8ACFF3BD85A23 CRC64;
MELDGEVEPS DRRTRGPDGA GFRSGRARGP LAWLKSANQN EGLVALVKRA RRRLPGDPEF
GDPLSVAGGD GPSVVARAAG RLLERDAATR EVSLATLQVW QALTERISGR PANPEVTLVF
TDLVGFSSWA LKAGDDATLR LLRRVAQVVE PPLLAAGGRI VKRMGDGSMV VFTEPVPAVR
AALAAKDAVK SVEVDGYTPR MRVGVHTGRP QHIGSDWLGV DVNIAARVME RATRGGVMVS
QTTLDRISDE DFDALNVTAK RVRRSLFAPQ PDGVPEGLTV YRLRAAAGGT GPSGGPAESG
EKPR
//
