ID G7CIX2_MYCT3 Unreviewed; 1075 AA.
AC G7CIX2;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE SubName: Full=Ribonuclease {ECO:0000313|EMBL:EHI12651.1};
GN ORFNames=KEK_17168 {ECO:0000313|EMBL:EHI12651.1};
OS Mycolicibacterium thermoresistibile (strain ATCC 19527 / DSM 44167 / CIP
OS 105390 / JCM 6362 / NCTC 10409 / 316) (Mycobacterium thermoresistibile).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycolicibacterium.
OX NCBI_TaxID=1078020 {ECO:0000313|EMBL:EHI12651.1, ECO:0000313|Proteomes:UP000004915};
RN [1] {ECO:0000313|EMBL:EHI12651.1, ECO:0000313|Proteomes:UP000004915}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 19527 / DSM 44167 / CIP 105390 / JCM 6362 / NCTC 10409 /
RC 316 {ECO:0000313|Proteomes:UP000004915};
RG Tuberculosis Structural Genomics Consortium;
RA Ioerger T.R.;
RL Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EHI12651.1}.
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DR EMBL; AGVE01000046; EHI12651.1; -; Genomic_DNA.
DR AlphaFoldDB; G7CIX2; -.
DR PATRIC; fig|1078020.3.peg.3383; -.
DR eggNOG; COG1530; Bacteria.
DR Proteomes; UP000004915; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0004540; F:RNA nuclease activity; IEA:InterPro.
DR GO; GO:0006396; P:RNA processing; IEA:InterPro.
DR CDD; cd04453; S1_RNase_E; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR019307; RNA-bd_AU-1/RNase_E/G.
DR InterPro; IPR004659; RNase_E/G.
DR InterPro; IPR003029; S1_domain.
DR NCBIfam; TIGR00757; RNaseEG; 1.
DR PANTHER; PTHR30001; RIBONUCLEASE; 1.
DR PANTHER; PTHR30001:SF0; RIBONUCLEASE G; 1.
DR Pfam; PF10150; RNase_E_G; 1.
DR SMART; SM00316; S1; 1.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
DR PROSITE; PS50126; S1; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000004915};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884}.
FT DOMAIN 424..501
FT /note="S1 motif"
FT /evidence="ECO:0000259|PROSITE:PS50126"
FT REGION 1..363
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 803..1075
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 13..29
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 82..102
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 139..156
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 179..193
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 194..212
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 261..278
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 315..333
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 344..363
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 859..901
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 937..1042
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1075 AA; 116086 MW; 4EC235CA29B4254B CRC64;
MLSRFDGRVR SAHSTVGPEE ADRVREVLAA GPEDSSPEDS STESAGQGNP GPEDAGPEDA
GPEETGPQKP EPTSVDPIAA PIEPQVDPPD SAVEPVPPAV TVDDPPAEDA AASVEVTPTE
VTDGPVSGGV EAAAPEAPET FQAQTTAHTT AQTAAPQDDD RPDYLPLFVA PKPIQIDIDD
EDDGFDDLDD DRGDDRADTG PDGDDDQGGR PTARRRRRGR RGRGRGRGEQ SGDDADGDST
GPGGGDTEEV AATAADQRDA DQSDESDDGS DDSGDDESTT TEGTTRRRRR RRRRKSGSGD
DTDNGVSPDD PPNTVVHERV PRTEKEERDQ AHSEIQGITG STRLEAKRQR RRDGRDAGRR
RPPILSEAEF LARREAVERV MVVRDKVRTE PPHQGARYTQ IAVLEDGVVV EHFVTSSASA
SLVGNIYLGI VQNVLPSMEA AFVDIGRGRN GVLYAGEVNW EAAGLGGQNR KIEQALKPGD
YVVVQVSKDP VGHKGARLTT QLSLAGRYLV YVPGATSTGI SRKLPDTERQ RLKEILREVV
PPDAGVIIRT ASEGVKEEDI RADVNRLQER WTQIEAKAAE LTEKKAGQAV ALYEEPDVLV
KVIRDLFNED FSRLIVSGDH AWNTINEYVS TVAPDLMPRL TKYEPASEDG PDVFAVHRID
EQLAKAMDRK VWLPSGGTLV IDRTEAMTVI DVNTGKFTGS GGNLEQTVTR NNLEAAEEIV
RQLRLRDIGG IVVIDFIDMV LESNRDLVLR RLTEALARDR TRHQVSEVTS LGLVQLTRKR
LGTGLLEAFS TTCTHCNGRG IVLHTDPVDS AQPSRRSDSG SRRSKRSKRS RSDDVQVVKV
PPHPPGEHPL FKAMAAASER ADSEAKDDTE ETGDGGKDAA KVAAKVKEKV AAEDRAKVGA
QDGVEEATPD GVETEAAAAT RAERVRTAVS GDAQASAGDL DDEDLANGDL EDEYLDDEDE
DEDLEDGDLE NGDLDDEDDD EDLEDGEIDV DLDEDLDDDI EVLNGDPDDE EADEDVDSYE
DPYDADADAD SDSDADADDE DSGDDRAAGR YAAPTVTRRP RRRAAVRPAG PPVQS
//
