ID G7DUH6_MIXOS Unreviewed; 724 AA.
AC G7DUH6;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE RecName: Full=Histone deacetylase {ECO:0008006|Google:ProtNLM};
GN Name=Mo00885 {ECO:0000313|EMBL:GAA94236.1};
GN ORFNames=E5Q_00885 {ECO:0000313|EMBL:GAA94236.1};
OS Mixia osmundae (strain CBS 9802 / IAM 14324 / JCM 22182 / KY 12970).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Pucciniomycotina; Mixiomycetes;
OC Mixiales; Mixiaceae; Mixia.
OX NCBI_TaxID=764103 {ECO:0000313|EMBL:GAA94236.1, ECO:0000313|Proteomes:UP000009131};
RN [1] {ECO:0000313|Proteomes:UP000009131}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 9802 / IAM 14324 / JCM 22182 / KY 12970
RC {ECO:0000313|Proteomes:UP000009131};
RX PubMed=21478649; DOI=10.2323/jgam.57.63;
RA Nishida H., Nagatsuka Y., Sugiyama J.;
RT "Draft genome sequencing of the enigmatic basidiomycete Mixia osmundae.";
RL J. Gen. Appl. Microbiol. 57:63-67(2011).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAA94236.1}.
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DR EMBL; BABT02000028; GAA94236.1; -; Genomic_DNA.
DR RefSeq; XP_014569666.1; XM_014714180.1.
DR AlphaFoldDB; G7DUH6; -.
DR STRING; 764103.G7DUH6; -.
DR GeneID; 26265998; -.
DR eggNOG; KOG1343; Eukaryota.
DR HOGENOM; CLU_007727_4_3_1; -.
DR InParanoid; G7DUH6; -.
DR OrthoDB; 124800at2759; -.
DR Proteomes; UP000009131; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0010468; P:regulation of gene expression; IEA:UniProt.
DR CDD; cd11600; HDAC_Clr3; 1.
DR Gene3D; 3.40.800.20; Histone deacetylase domain; 1.
DR InterPro; IPR019154; Arb2-like_domain.
DR InterPro; IPR000286; His_deacetylse.
DR InterPro; IPR023801; His_deacetylse_dom.
DR InterPro; IPR037138; His_deacetylse_dom_sf.
DR InterPro; IPR023696; Ureohydrolase_dom_sf.
DR PANTHER; PTHR10625:SF4; HISTONE DEACETYLASE 6, ISOFORM G; 1.
DR PANTHER; PTHR10625; HISTONE DEACETYLASE HDAC1-RELATED; 1.
DR Pfam; PF09757; Arb2; 1.
DR Pfam; PF00850; Hist_deacetyl; 1.
DR PRINTS; PR01270; HDASUPER.
DR SUPFAM; SSF52768; Arginase/deacetylase; 1.
PE 4: Predicted;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000009131}.
FT DOMAIN 69..377
FT /note="Histone deacetylase"
FT /evidence="ECO:0000259|Pfam:PF00850"
FT DOMAIN 446..617
FT /note="Arb2-like"
FT /evidence="ECO:0000259|Pfam:PF09757"
SQ SEQUENCE 724 AA; 79666 MW; 4FD85BD7E0BABE97 CRC64;
MIPTNGVTPQ KGIVGGRIAT EALLAPALVI HQRNEQTLCV QPRTGYVYDK HMMLHRDEYG
DPMLPEDQHP EQPSRISRIM HTILEADLLK CMLRLQIRSA SREEACLIHS AQLWDELEIT
STLDQAVLDD REFRQHLRYH SLYVNHHTAT CAKLSLGGVL VSAIAVAEKR VSNAFAIVRP
PGHHADPDQS SGFCFFNNVA VTAKYLLCHY REGPAPIQRI LILDWDIHHG NGTQTAFYDD
PNVLFVSIHR FDIRGGERFY PGRPEADMTF VGEGAGRGKN VNIPWDQAAM GDADYLYAFD
TIVMPLAREF APDFVLISAG FDAAKGDELG GCLVSPAGYA HMTHRLASLA GGRLVAALEG
GYNIEAISQS ALACIRVMLG DAPPALPSLA PCASAVKTIH DVVAIQSRFW KTMRPRYEPL
SDDILPLATE LNRALLPFEA IVKRKHSQMI SVALGEPTLS SHFDRQVFVS SSIRTATKAI
LWIHEGSVLS IKLNAATGEP ASSESFIYDK SELIYRLSND QQWAVVDVNV TLPAPLHSHS
KEGKRLRTAL IAHVWHSLFR NSDISMSEID RVVIIADGRG CQAFSDVMAD VDLADLEQIS
AACVLTPSPL QPLRPLRATA GWSKKSVLHI ASESTDAKTD AKTLRRQAML KTTYAEGWQC
DLAKVLSDMV GSHLDQRASI DAQPDQRMAI HCSLRVRKDG HRSSACQIRL TSAAQPVLVG
TCSV
//
