ID G7DW36_MIXOS Unreviewed; 3157 AA.
AC G7DW36;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE RecName: Full=Vacuolar protein sorting-associated protein {ECO:0008006|Google:ProtNLM};
GN Name=Mo01496 {ECO:0000313|EMBL:GAA94842.1};
GN ORFNames=E5Q_01496 {ECO:0000313|EMBL:GAA94842.1};
OS Mixia osmundae (strain CBS 9802 / IAM 14324 / JCM 22182 / KY 12970).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Pucciniomycotina; Mixiomycetes;
OC Mixiales; Mixiaceae; Mixia.
OX NCBI_TaxID=764103 {ECO:0000313|EMBL:GAA94842.1, ECO:0000313|Proteomes:UP000009131};
RN [1] {ECO:0000313|Proteomes:UP000009131}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 9802 / IAM 14324 / JCM 22182 / KY 12970
RC {ECO:0000313|Proteomes:UP000009131};
RX PubMed=21478649; DOI=10.2323/jgam.57.63;
RA Nishida H., Nagatsuka Y., Sugiyama J.;
RT "Draft genome sequencing of the enigmatic basidiomycete Mixia osmundae.";
RL J. Gen. Appl. Microbiol. 57:63-67(2011).
CC -!- SIMILARITY: Belongs to the VPS13 family.
CC {ECO:0000256|ARBA:ARBA00006545}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAA94842.1}.
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DR EMBL; BABT02000047; GAA94842.1; -; Genomic_DNA.
DR STRING; 764103.G7DW36; -.
DR eggNOG; KOG1809; Eukaryota.
DR HOGENOM; CLU_000135_0_0_1; -.
DR InParanoid; G7DW36; -.
DR Proteomes; UP000009131; Unassembled WGS sequence.
DR GO; GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
DR InterPro; IPR015412; Atg2/VPS13_C.
DR InterPro; IPR026847; VPS13.
DR InterPro; IPR026854; VPS13-like_N.
DR InterPro; IPR049424; VPS13_C.
DR InterPro; IPR031645; VPS13_DH-like.
DR InterPro; IPR031646; VPS13_extend_chorein.
DR InterPro; IPR031642; VPS13_mid_RBG.
DR InterPro; IPR009543; VPS13_VAB.
DR PANTHER; PTHR16166:SF93; INTERMEMBRANE LIPID TRANSFER PROTEIN VPS13; 1.
DR PANTHER; PTHR16166; VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN VPS13; 1.
DR Pfam; PF09333; ATG2-VPS13_C; 1.
DR Pfam; PF12624; Chorein_N; 1.
DR Pfam; PF21679; VPS13_C; 1.
DR Pfam; PF16909; VPS13_DH-like; 1.
DR Pfam; PF16908; VPS13_ext_chorein; 1.
DR Pfam; PF16910; VPS13_mid_rpt; 1.
DR Pfam; PF06650; VPS13_VAB; 1.
PE 3: Inferred from homology;
KW Lipid transport {ECO:0000256|ARBA:ARBA00023055};
KW Reference proteome {ECO:0000313|Proteomes:UP000009131};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 2..115
FT /note="Chorein N-terminal"
FT /evidence="ECO:0000259|Pfam:PF12624"
FT DOMAIN 139..368
FT /note="Vacuolar protein sorting-associated protein 13
FT extended chorein"
FT /evidence="ECO:0000259|Pfam:PF16908"
FT DOMAIN 594..829
FT /note="VPS13 middle RBG modules"
FT /evidence="ECO:0000259|Pfam:PF16910"
FT DOMAIN 1924..2493
FT /note="Vacuolar protein sorting-associated protein 13 VPS13
FT adaptor binding"
FT /evidence="ECO:0000259|Pfam:PF06650"
FT DOMAIN 2749..2925
FT /note="Vacuolar protein sorting-associated protein 13 DH-
FT like"
FT /evidence="ECO:0000259|Pfam:PF16909"
FT DOMAIN 2933..3012
FT /note="Atg2/VPS13 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF09333"
FT DOMAIN 3023..3130
FT /note="Intermembrane lipid transfer protein VPS13 C-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF21679"
FT REGION 1364..1398
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1706..1738
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1716..1738
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 3157 AA; 352896 MW; 1F78696ACF282028 CRC64;
MLEGVVAGVL NRTLSAYVDN LDTSQLNLGI WSGDVKLRNL RLKKEALDKF RLPINVTEGY
LGELTLNIPW TNLKGKPVRV VIDNVYLLAE PAGETNFDLE EDERRAQQVK MEKLENAELL
TTQPSAGMSA EEEQKNQSFV SSLVARILDN LQITVKNIHV RYEDRLSVPG HPFSVGLTLA
GFSAVSTDEH WQPTFLHNSD KGIHKLAKLD SLAIYFDTDS TSLGGQSQAD AMKTFVSLIA
TETSTSSHQF ILKPVSGAGR LIMNKHMDGQ TPKIDAELFF NELGFVLDGD QYRDALSMVD
LFHFYTRQHQ YRKFRPPEIE FEKSKSRALL RFAGSAILNE VHEKNRVWSW SYFAERRDDR
KEYIQLFKLV AKDANDVTAK ARIGELERKL GYKDIRFYRS IARSEMRKEQ ATARKTAEQE
RLQAGPVNRG WVGWIWGGGK SNGSDDQPQD LLNTQQRKEL YAAIDWDEKD AVAASVDLPR
DTLQLRLKAK LDTGSFALRE DPHGKNTDII SMVFDAFSAD VLQRPDSLEA ILALGGMRVY
DGTQPNTLHP QIVRVKQEKT AIAHRSNSQD KLGTALASVK QESDPDNPFF YVKFEKNPLD
ERADMGLTVR MRYMEIIYHR GYVERIVAFF KPPASQLESV SALVDVASET LDGIRKESRA
GLEYALQTHS TVDIRLDMNA PIIVVPEDVT KEICQHIVLD AGHISIESGL ADKSAIEDIR
SKQKEVYTDD DFHKLESLMY DKFFIKLDSA QLLMGDTLEA CLGALEGHAG PELHVLERIN
LSFTAENSIL SKAPNLTRFK VSGHLPDLTV NFSDRKYKIL MRMIDVAVPK FGEDEPEPEH
VKPNIGPRKP TQTFISAPMY FSNKEVDHEL HLDGEHHEQE EEQKEDAGKD DVFYDTQDTG
EGGASYKQKT FELSFVVDKL QAAIYKSDPK QVESDKLLVK TVLEGFDLMF SLRPYDMEVD
ITLRALHVDD AMVEEGTVFQ HLITSERPGQ NGQSASEDLV HIKYSQVQPD SPEFMTVHEA
FNKSVEIQFA TINVIVTRAS ILLLFDFVMS TFASGDESAS DPDTPSTEEA TLVQVGEPIV
EKLRVKVKLT SVVLILNDDG VRLATLSLSA ADVMVLLRGA TIRVAARLGS LDFVDDLEHA
GVPLNSPARK MLTIDGEELA DLQYETLDPA DDERPYDTLI RLKTGSLRFT FLEVPVHRVL
RFLTKFARMK SLYDRATQAA AQQAATELES RLHYDISIAS PIIVFPRSSH SKDRIIAQLG
TIEATNEFST STDGKLITKI RAALKSVALT SEIQHDGQLN TLPILEKLDL SVSIQQASGI
DHTQQTIEPD TRINARMSDV KIGLTQAQYG FAMSLSQSIP RALASTQEEL DEDAEEEAAH
PMPAPPITNG ETSPDENKET VDLLPELSSI AHGQNGEIVR LWISLELSFA VQSVGLELYT
AAAIDPATLD SASLARFALT GTKLSFKSLN NGSSEAELSL SKFTLHDTRT AVQTKWREII
PASKHESAQF MVAYSAAGGK DPIAIANITI DSPTLVFSVD PLFALLNYFT SAFDSAAPAV
KSAETKADEA EEENEEIQPA QSVSALSYRV NLVQPKIMLL ADPNRHDSEA VVLTIDRLQM
AQQGTLVLTI DQLGMFLCKM DAQSNTLRFL DSFDLSLSLD TREDAGRQLT NIEMRVQPLT
FRLSFRDVKI IMLIVNRAIE LSGEASPAPA DAVEMPAKDR STERRASVTE ARPGLPKRAT
SERAVKAGLV MSKETLRATC EGFQLVLIGD MHELPMLDVK AGKFSAKASD WSADLKASLT
IDTFINYYNL RNSHWEPLLD PWEFTISVSR SQAQESTALA LTSKKRAEVN ITATFIELGL
TTMAILEQQG ESVMRMKRGQ NAPFEIRNRT GYPIMLAAES DHKQRRKPAQ RLEDGASMPW
RFDDWRVMRE NVNSSSHNSL SVQIEGTAWE RLRHINVDRE GEQIHALRPK VDNTTHRVMC
DIKLQDNVKI VTFRSAFRIQ NMTLVPVEMV IVDSTGKKAS SVYKIPPGEY CPVPIEAAYN
QKLRIRPDPG FGYLWSSESF DWQDLVKRPS RAIVCKSQEK EASFRFQCFT EYDRNDPLIR
VYPRLTLKLR APIEIENLLP YDIRYRVYDK AREHNWTSFL RKGGVSPMHI AELSHLLLLS
VELQDTDFKR SEFAIINTDN PDDLPIEEVL QLEDSAGLKL NLRVNYERHP DSGGAFKVQV
YSPYIFINNT GSDFTIATKS LMGTAKGVVG NGEGSPGTSG TVEKPLLFSY ATVDRRNRAL
LRFGHSAWSK PLSFEAIGTE SEVSVPSHDG KEEMRIGLKV TEGTGSYKLT KVVIVYPRFI
LKNNYRRSIR VREAGSTNSI LVQPDVMCPL KWWRTNQEPL LSVAYDETSS AWCSPFKVKD
IGRVHSRMKT QSGQESLLRA EILLEGSKIF IRVAEEKDKW PFVVRNSSKY PFSVSQSQED
FRDRQEARKL PPAKSYRVEP GQTLQYAWDV PSASDKLLRL EISGKDRLLN IMEIGALLPF
RFPISNRSHA VVSLDVKAEG PTQALIISDY AEQDSVYTQQ VRPGSLSRQN STTSVNQVDF
EARDVQVRTT LTVKIQMEGL GISLVNRSMS ELLYASFRGF ELNYSDSSTN QAVNLSVKWI
QIDNQLFGGV FPILLYPAVI PKDGRELELR PSFQASVILL KDSEHGVTYF KYASLLLQEM
SIEVDEDFLF ALLDFSKLEG ASWQKDPPSI LTDESGTLAE PAEVAGAGDV YFESLHLQPM
QLDISFMRTE TVNSEQKVFA SNRNPVTFFL NALTMALGNV NDAPIRLNAL MIENVRISYP
ELANRVVLHY SQDFFGQLYR VLGSADFLGN PIGLFNNVSS GVKDIFYQPY EGLVMHGNRD
IGLGIARGAG SFVKKTVFGV TDSMAKVTGS IGKGLSAATL DKEWQSKRRM RQFRNKPKHA
LYGFTAAGNS FFTSVASGIE GLAMKPIEGA DAGGAAGFFK GVGKGLVGAV TKPVVGVFDA
ANNFTEGIRN TTTVFDDSAI DRVRLPRYVA SDDVLRPFQE REALGQSWLK SLDNGAYFSE
RYVAHVDIPN DGDDLLVVLT ETQILLVRAL KLKVGWAVPL SDLQTISLEP KGIALTLRRG
ATGPFLNLPD QSARLWFFKH IERVVRNYNS QRKTYTE
//
