ID G7E111_MIXOS Unreviewed; 977 AA.
AC G7E111;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE RecName: Full=DUF726 domain protein {ECO:0008006|Google:ProtNLM};
GN Name=Mo03189 {ECO:0000313|EMBL:GAA96521.1};
GN ORFNames=E5Q_03189 {ECO:0000313|EMBL:GAA96521.1};
OS Mixia osmundae (strain CBS 9802 / IAM 14324 / JCM 22182 / KY 12970).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Pucciniomycotina; Mixiomycetes;
OC Mixiales; Mixiaceae; Mixia.
OX NCBI_TaxID=764103 {ECO:0000313|EMBL:GAA96521.1, ECO:0000313|Proteomes:UP000009131};
RN [1] {ECO:0000313|Proteomes:UP000009131}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 9802 / IAM 14324 / JCM 22182 / KY 12970
RC {ECO:0000313|Proteomes:UP000009131};
RX PubMed=21478649; DOI=10.2323/jgam.57.63;
RA Nishida H., Nagatsuka Y., Sugiyama J.;
RT "Draft genome sequencing of the enigmatic basidiomycete Mixia osmundae.";
RL J. Gen. Appl. Microbiol. 57:63-67(2011).
CC -!- SIMILARITY: Belongs to the TMCO4 family.
CC {ECO:0000256|ARBA:ARBA00009824}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAA96521.1}.
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DR EMBL; BABT02000102; GAA96521.1; -; Genomic_DNA.
DR RefSeq; XP_014567435.1; XM_014711949.1.
DR AlphaFoldDB; G7E111; -.
DR STRING; 764103.G7E111; -.
DR GeneID; 26265022; -.
DR eggNOG; KOG2385; Eukaryota.
DR HOGENOM; CLU_001695_0_0_1; -.
DR InParanoid; G7E111; -.
DR OMA; AIQNMEL; -.
DR OrthoDB; 8526at2759; -.
DR Proteomes; UP000009131; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR007941; DUF726.
DR PANTHER; PTHR17920:SF24; LIPASE MIL1-RELATED; 1.
DR PANTHER; PTHR17920; TRANSMEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 4 TMCO4; 1.
DR Pfam; PF05277; DUF726; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000009131};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 432..457
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 477..499
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 1..60
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 242..318
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 774..807
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 832..890
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 933..977
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 23..42
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 777..804
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 861..879
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 940..977
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 977 AA; 105459 MW; EE39D62A41F1257F CRC64;
MYASWQDDDE WQDMPIIRSA EPDASSFGSQ PVASSSSTRR ASHRYDAPLA TASTSVGADH
ASVNARGTHI DAGQPGEDWR EKQSLDELVY TRLELDDDPD EDQVHMKTQF LFDDDKGMTP
LSQMQATKTL LTEGQRVAYV ALCRLVTMDI CQALRKGKHK ELEAAAESAL NWAHKIMGRL
YHHMDIDTSE QKMIEQLVEH GVTADDLVPS LVVTHTVPNP EYDPVAAKAA ALEADRVAAE
HQAAQEAAAQ QRALPPTFEE GDPPPDYAEP AVRASLALTD APRPLTPTIG KAARRQSAAQ
VPLPPSPSTP KPPDLEKPAL AKRESDNLIS PLPNTLPGVS TELTSADETV TLDIRWTVLC
DLFLALIADS VYDARSRVLL CRMAEHLGLE WMDVVRFERR LTEAMDIQES VKNSKQDEVL
EQRRVKGKSK RYVMMGLATL GGGLVIGLSA GILAPAIGAG LGAAFTTIGV TGTTGFLAGT
GGAALITTGG IAAGGGIAVK GMAKRTQHVK TFEFYPLHNN RRVNFYITVP GFMEGKLDDI
RLPFSVIDPV MGDFFSLLWE PQTMQDTGNA LKILTSEVLT QAGQQVLAMT IMTALMSALQ
WPVMLTKLGY LIDNPWSNAL DRAKAAGAVL ADVLKNRSLG VRPVSLVGFS LGARVIFYAL
KELARAKAFG VVQEVYLMGA TVTASRKSWR EARGVVCGRF VNAYATNDWI LGYLFRATTG
GLGTVAGLRP IEQVPDMENV DVTDIVVGHM SYRACMPLIL DRIGFKVTAL TFDEPDNDPL
TGDREVLTPE EEEARREAKK NKGVFKMFRS KSKQNAAQSA SLEAAAKAST TAAAAASAPA
EEDDDDDLPP REDHASTEYA PSPDTADSTM PNSPREGSEA QFNLDKIRQV LAQGGPATSV
DVAQSMRTAP VNGALPARTP TSSEFSFEAA ARRNGIDTPE TLSFAGQDGS ITSTRPSFSV
ERAPAPTKQT TASNPWS
//
