ID G7E1X3_MIXOS Unreviewed; 1717 AA.
AC G7E1X3;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE RecName: Full=PXA domain-containing protein {ECO:0008006|Google:ProtNLM};
GN Name=Mo03559 {ECO:0000313|EMBL:GAA96886.1};
GN ORFNames=E5Q_03559 {ECO:0000313|EMBL:GAA96886.1};
OS Mixia osmundae (strain CBS 9802 / IAM 14324 / JCM 22182 / KY 12970).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Pucciniomycotina; Mixiomycetes;
OC Mixiales; Mixiaceae; Mixia.
OX NCBI_TaxID=764103 {ECO:0000313|EMBL:GAA96886.1, ECO:0000313|Proteomes:UP000009131};
RN [1] {ECO:0000313|Proteomes:UP000009131}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 9802 / IAM 14324 / JCM 22182 / KY 12970
RC {ECO:0000313|Proteomes:UP000009131};
RX PubMed=21478649; DOI=10.2323/jgam.57.63;
RA Nishida H., Nagatsuka Y., Sugiyama J.;
RT "Draft genome sequencing of the enigmatic basidiomycete Mixia osmundae.";
RL J. Gen. Appl. Microbiol. 57:63-67(2011).
CC -!- SIMILARITY: Belongs to the sorting nexin family.
CC {ECO:0000256|ARBA:ARBA00010883}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAA96886.1}.
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DR EMBL; BABT02000108; GAA96886.1; -; Genomic_DNA.
DR STRING; 764103.G7E1X3; -.
DR eggNOG; KOG1442; Eukaryota.
DR eggNOG; KOG2101; Eukaryota.
DR HOGENOM; CLU_002131_1_0_1; -.
DR InParanoid; G7E1X3; -.
DR Proteomes; UP000009131; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0043226; C:organelle; IEA:UniProt.
DR GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR Gene3D; 3.30.1520.10; Phox-like domain; 1.
DR Gene3D; 1.10.167.10; Regulator of G-protein Signalling 4, domain 2; 1.
DR InterPro; IPR003114; Phox_assoc.
DR InterPro; IPR001683; PX_dom.
DR InterPro; IPR036871; PX_dom_sf.
DR InterPro; IPR016137; RGS.
DR InterPro; IPR036305; RGS_sf.
DR InterPro; IPR044926; RGS_subdomain_2.
DR InterPro; IPR013937; Sorting_nexin_C.
DR InterPro; IPR004853; Sugar_P_trans_dom.
DR PANTHER; PTHR22775; SORTING NEXIN; 1.
DR PANTHER; PTHR22775:SF3; SORTING NEXIN-13; 1.
DR Pfam; PF08628; Nexin_C; 1.
DR Pfam; PF00787; PX; 1.
DR Pfam; PF02194; PXA; 1.
DR Pfam; PF00615; RGS; 1.
DR Pfam; PF03151; TPT; 1.
DR SMART; SM00312; PX; 1.
DR SMART; SM00313; PXA; 1.
DR SMART; SM00315; RGS; 1.
DR SUPFAM; SSF64268; PX domain; 1.
DR SUPFAM; SSF48097; Regulator of G-protein signaling, RGS; 1.
DR PROSITE; PS50195; PX; 1.
DR PROSITE; PS51207; PXA; 1.
DR PROSITE; PS50132; RGS; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000009131};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 31..52
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1388..1408
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1420..1445
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1457..1478
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1484..1502
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1509..1527
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1533..1553
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1574..1597
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1603..1626
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1661..1680
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 113..331
FT /note="PXA"
FT /evidence="ECO:0000259|PROSITE:PS51207"
FT DOMAIN 465..601
FT /note="RGS"
FT /evidence="ECO:0000259|PROSITE:PS50132"
FT DOMAIN 933..1053
FT /note="PX"
FT /evidence="ECO:0000259|PROSITE:PS50195"
FT REGION 659..697
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 751..782
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 904..931
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 668..685
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1717 AA; 187441 MW; 9B559A80132D909E CRC64;
MRPTQALAAA ASLLAVLAAL LGPFKLLFAL LRWSTFAALS WLLLNGLAII LLQYRRTQVR
QQAVARGLKA STDGRYDIPP LAFTTPAAWS ALQTRLAWAD PDETRRPLHP QLSSKVSEEI
DTVIKLVIRD FVLKWYDDIV PASAPGRTFP RIIEDIIRHS LTSILQRIDT INITKLIAST
VVQRTTDHIE ACKAAERDLR DVSDTRTRKR NIKHAEAFTL NTSDSGSEDI ELLMAKRYAS
HLNTTRAHSH NSIKGLHKAI DVAATNTRPS EEAHLRDVVG RLLRSILPDS ANQSPTVRIM
AREIVACSIV LPVLEMLADP DLWNRLIDDR AGAALREQKM VSQLRQALDA APIGHRVAAD
EISHLTNQAQ FDAFARSAGR IKQLSELKRL RNDVALGLRR SQLLLQSSTD KSEIDLLRSH
IDRLYQVKVK VDDAVRGVEG HRGDTLARAI SNTHSAAFND AARPRLRQIL GSASAVSYFM
EFMDRRHRAL LVQFWLSVEG LKDPLSEVDV AHVNGEESST LAEDLEMIYR TYFANDQVRS
DDIQKLYLLE AFANSETTLA DSSRLLKVRD AVVGLQVDVL SQMEESDLSD FQRSELYYKA
LDALSAAQPT TPDVKLVLPT EASAELSQPS TGIRTPILRA LSASTLPLSM LQQTVQARAV
SQPLTNRPDS EHAKRDERRD GLARPDTSPT RLSAAVLPPR MSDSIDFLIG SSESAETQQR
PPLFTDEKAE QAAAEAQTMR DVQDALTSIL ASSESSKQAE RGRGRPASVR SHASTESVLS
RPDTFLVAGL PGSIPTRPAE KRTISDTTNM MSRRDAEAAS APARRKAVFE DFDSDLEDGE
EADASQEAVL VNSADDTAAS SPDVNRITAR IEELQSQSGL IETLLARAEL TGNQSEMKIL
SRSGDALRRE LRELNYRLQQ IENQRSQSRI RPDRTSISIG SVTQGQANGS TFVLYLIEVR
QLANDGSFES GWLCTRRYSE FVTLHATLRA KYASARGIEL PSKKVVSSLA ATDAFVETRR
AGLEKYLKAL VCDEQVSQSP ELQSFLSRQH ISLPNLEKGA AVPVRAASQG VVRQIVRTVT
TGIDELFSGP SMIDMIVHRL SQQAADFAGL SGSAADEDGM IAHALQVTQS SNTVGLASSN
GEGLTYFTAP ICDLLIEVFD LKEKNSWLRR QAILILLQQV LGGTIERKFR EAVAALVRED
SLLATIGLVK SMMWPGGVLK APGVPRTPSE RLATRDAAYR KLSTLMPDVA ANVIGRSNAR
RGARRVFAAV QYRRLNQHLI YSILDDVIHA AFPEPSFLAE LRLLAARQTS MTTMRQRPSG
DGTEAAIPLL SPANHDVDEV DNLGRLSSSL SRSPSRSPAG LREAELANGS ANGFSSIKAG
PPARESTNLQ VAGAVTFYMV AALTMIVANK WVLNAVALPL YFLFLQLVVA VILLWMTALF
GYYDLPATWN KKVLRGLAPF LTINTLGLAL NTFTLQYVDA SFYQIARGLV LPFTAILSYH
FLTVVPSKAT IASIGVVCIG FALGVGFEDM SVSLLGIILG VGSSATTAAH AIAIKRALPV
VQNSTMNLVW YANLMTALAL LPFAVIVETG GLLSLIAEGG HALYTFVAGT LLTGFFGFAI
CIAGFISIKV TSPTTHMISS AVRGVLQTFL GVALFHDIVT YGRASGIAVI ILGSVLYTWS
MSRAPPPPKK PEHVALPGDD EAIEIDTLPK HRSSNEK
//
