ID G7E4I8_MIXOS Unreviewed; 1600 AA.
AC G7E4I8;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 27-MAR-2024, entry version 74.
DE RecName: Full=Zn(2)-C6 fungal-type domain-containing protein {ECO:0008006|Google:ProtNLM};
GN Name=Mo04427 {ECO:0000313|EMBL:GAA97748.1};
GN ORFNames=E5Q_04427 {ECO:0000313|EMBL:GAA97748.1};
OS Mixia osmundae (strain CBS 9802 / IAM 14324 / JCM 22182 / KY 12970).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Pucciniomycotina; Mixiomycetes;
OC Mixiales; Mixiaceae; Mixia.
OX NCBI_TaxID=764103 {ECO:0000313|EMBL:GAA97748.1, ECO:0000313|Proteomes:UP000009131};
RN [1] {ECO:0000313|Proteomes:UP000009131}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 9802 / IAM 14324 / JCM 22182 / KY 12970
RC {ECO:0000313|Proteomes:UP000009131};
RX PubMed=21478649; DOI=10.2323/jgam.57.63;
RA Nishida H., Nagatsuka Y., Sugiyama J.;
RT "Draft genome sequencing of the enigmatic basidiomycete Mixia osmundae.";
RL J. Gen. Appl. Microbiol. 57:63-67(2011).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAA97748.1}.
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DR EMBL; BABT02000134; GAA97748.1; -; Genomic_DNA.
DR RefSeq; XP_014564797.1; XM_014709311.1.
DR STRING; 764103.G7E4I8; -.
DR GeneID; 26266441; -.
DR eggNOG; ENOG502QVC1; Eukaryota.
DR HOGENOM; CLU_244329_0_0_1; -.
DR InParanoid; G7E4I8; -.
DR OrthoDB; 1440070at2759; -.
DR Proteomes; UP000009131; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0006351; P:DNA-templated transcription; IEA:InterPro.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd12148; fungal_TF_MHR; 1.
DR CDD; cd00067; GAL4; 1.
DR CDD; cd01786; RA_STE50; 1.
DR Gene3D; 1.10.150.50; Transcription Factor, Ets-1; 1.
DR Gene3D; 4.10.240.10; Zn(2)-C6 fungal-type DNA-binding domain; 1.
DR InterPro; IPR000159; RA_dom.
DR InterPro; IPR001660; SAM.
DR InterPro; IPR013761; SAM/pointed_sf.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR InterPro; IPR007219; Transcription_factor_dom_fun.
DR InterPro; IPR036864; Zn2-C6_fun-type_DNA-bd_sf.
DR InterPro; IPR001138; Zn2Cys6_DnaBD.
DR PANTHER; PTHR47338:SF30; ZN(2)-C6 FUNGAL-TYPE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR47338; ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED; 1.
DR Pfam; PF04082; Fungal_trans; 1.
DR Pfam; PF07647; SAM_2; 1.
DR Pfam; PF00172; Zn_clus; 1.
DR SMART; SM00906; Fungal_trans; 1.
DR SMART; SM00066; GAL4; 1.
DR SMART; SM00454; SAM; 1.
DR SMART; SM00326; SH3; 2.
DR SUPFAM; SSF47769; SAM/Pointed domain; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR SUPFAM; SSF57701; Zn2/Cys6 DNA-binding domain; 1.
DR PROSITE; PS50200; RA; 1.
DR PROSITE; PS50105; SAM_DOMAIN; 1.
DR PROSITE; PS50002; SH3; 1.
DR PROSITE; PS50048; ZN2_CY6_FUNGAL_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000009131};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 64..103
FT /note="Zn(2)-C6 fungal-type"
FT /evidence="ECO:0000259|PROSITE:PS50048"
FT DOMAIN 846..909
FT /note="SAM"
FT /evidence="ECO:0000259|PROSITE:PS50105"
FT DOMAIN 1359..1429
FT /note="Ras-associating"
FT /evidence="ECO:0000259|PROSITE:PS50200"
FT DOMAIN 1462..1523
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 1..56
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 794..834
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 998..1035
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1161..1192
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1267..1359
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1435..1466
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..43
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 794..831
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1168..1192
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1267..1283
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1296..1316
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1451..1466
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1600 AA; 177122 MW; AAFAE451DE41CA6D CRC64;
MSVRPASQID SSPPAERSGP SLQTNFFAQE SAGPSTSAGS AQEGDESDYK PRKRRQPALS
RFEACKRCRA RKVRCDTVRP ACGPCLRSAN AQGIDVHLVM CEYDKPTTNT PALFHPMPPG
PPLGVQSQES VRQLTTSALY PLEQKIASLE HELAQYRAQA PGVPPFGLPP MTNVATHVTQ
NYIFPPNAPI SAEPPFMNEM LYPAWPPSLP SPPLVISLCT AFFSKPHVCG HTINRGRFLS
SLNLLPTHPD FPHTCLIHAV CCVGSMLVSP HAFNLSREPY WQRQHDRSPA DYHARVATET
WDNTLVRGAK LFHVAQAMCI ICYYTYSRAK FVEVWLWSGV ATRLCTPLGL NNLQRLEFTR
GQDIRDRLRK TNYLAPTTDR YAHHERAETF WMSFLCDRFA SANTGWASAI DEADVTTLLP
AQYAEALERT REDVAVAALS IHSSTFFTSH PDGLVGPRQL NIKAFVLLGR VVNFVQRLPA
PFGHGEPVPG RPKYDYTAGV EFNKLDAEVV AFRLSFPPAY RHFAQALGGA AATIDIELVT
AHAVPHCCTM ILHEPFVSAR EHDLAMRRCL LSARAMLAMI QTLRNSSFEL GLLTPYVVFC
WSVAGRTLIR EFAIKTSRRL PADDVAAEVN LVIQALELFG MHCPLGNVVA QTLRRLFADH
ESCIPKDDAA SAVNVSTNIE YWRDREGQTI QPQAQMEPSL VQTPHGGPPH YNLTRYAASL
GPHTPAPDRP RSVNGRDLSQ ILFDLEQSSH SQALEPGQLQ SLLDHIVVEP HVRAVRFNSG
CVVLCDLTSS SAISSKMSED QSSSPVSARS FRTPAESQSE ASWTERRQDS PVSSRGPLPI
LALEHWTVSQ VERFFAHHDL AAVGALCTNL QIDGSLLAHL GHDDLKELGI LSVGTRLKIL
RAVYDVKIES CSEVVTGDWS PPCPSLGPLR SQRECYSPPS TPPDLVSHDQ QLVLNELYGL
REEIRELKEL VRLALPIEHT RAISPVADVK RAGVGCSHLP RLSKEEPSSP ADPSRRVNAL
GASPEPPRHI DSPRPVINYT APPQTPTAID QSPRAQVFRQ NEQSARPENR AVEKFRASPD
MRLPSPRQMT QAEHDHTIDT NKPVSKLSQL TRTLRIVSST KTVSPVSPAL LSGGSSMTTC
ALQEAQIVKF STEKPALKRA HSLGKMGGGN LQLNSASSSS PSSPCSVSLG RSMSERQPLR
SYWYEQRYIP KSAQANSLTF DNTKRIARYE TDFAGLRNIA KSDAAKSSDL QEILRQSNFA
VRPMRSAQQF AHTARQARSE PSTPQAVPAP APAPRLSRSA STSESIRVTT SPTEYQPADR
EIPLLKSEQT LRPVAQLTRN VTLSRPREAG KPRESPSHHD TCFQILPLAL KKYNLRGGWQ
EYVLFIQHDG PDGKPMKRCL SYNERPREIF DRLKEQNANP VFSISHLREM RSPVAAHGDD
TRVRAPRTPP ARSVSSATQH TPTSPNAIVV FPHTANKSGQ ISLDIGERCE IIARDEHGSV
LVRKRSSSNT GLIPLSCLLE LKTGFAESWS DDPEAVQTNF VRGKAVIHLD CEGEHEVGLR
QGEQVRVYCR AQHWLYVGKE DKTARPRMGW TPAWLVELLE
//
