ID G7E7L5_MIXOS Unreviewed; 1118 AA.
AC G7E7L5;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE RecName: Full=U-box domain-containing protein {ECO:0000259|PROSITE:PS51698};
GN Name=Mo05513 {ECO:0000313|EMBL:GAA98825.1};
GN ORFNames=E5Q_05513 {ECO:0000313|EMBL:GAA98825.1};
OS Mixia osmundae (strain CBS 9802 / IAM 14324 / JCM 22182 / KY 12970).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Pucciniomycotina; Mixiomycetes;
OC Mixiales; Mixiaceae; Mixia.
OX NCBI_TaxID=764103 {ECO:0000313|EMBL:GAA98825.1, ECO:0000313|Proteomes:UP000009131};
RN [1] {ECO:0000313|Proteomes:UP000009131}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 9802 / IAM 14324 / JCM 22182 / KY 12970
RC {ECO:0000313|Proteomes:UP000009131};
RX PubMed=21478649; DOI=10.2323/jgam.57.63;
RA Nishida H., Nagatsuka Y., Sugiyama J.;
RT "Draft genome sequencing of the enigmatic basidiomycete Mixia osmundae.";
RL J. Gen. Appl. Microbiol. 57:63-67(2011).
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC {ECO:0000256|ARBA:ARBA00004906}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the ubiquitin conjugation factor E4 family.
CC {ECO:0000256|ARBA:ARBA00007434}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAA98825.1}.
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DR EMBL; BABT02000165; GAA98825.1; -; Genomic_DNA.
DR RefSeq; XP_014566998.1; XM_014711512.1.
DR AlphaFoldDB; G7E7L5; -.
DR STRING; 764103.G7E7L5; -.
DR GeneID; 26268993; -.
DR eggNOG; KOG2042; Eukaryota.
DR HOGENOM; CLU_003224_2_1_1; -.
DR InParanoid; G7E7L5; -.
DR OMA; FKMLPEY; -.
DR OrthoDB; 1554at2759; -.
DR UniPathway; UPA00143; -.
DR Proteomes; UP000009131; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0000151; C:ubiquitin ligase complex; IEA:InterPro.
DR GO; GO:0034450; F:ubiquitin-ubiquitin ligase activity; IEA:InterPro.
DR GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR GO; GO:0030433; P:ubiquitin-dependent ERAD pathway; IEA:InterPro.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR019474; Ub_conjug_fac_E4_core.
DR InterPro; IPR045132; UBE4.
DR InterPro; IPR003613; Ubox_domain.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR13931:SF2; UBIQUITIN CONJUGATION FACTOR E4 B; 1.
DR PANTHER; PTHR13931; UBIQUITINATION FACTOR E4; 1.
DR Pfam; PF04564; U-box; 1.
DR Pfam; PF10408; Ufd2P_core; 1.
DR SMART; SM00504; Ubox; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS51698; U_BOX; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Reference proteome {ECO:0000313|Proteomes:UP000009131}.
FT DOMAIN 1036..1110
FT /note="U-box"
FT /evidence="ECO:0000259|PROSITE:PS51698"
FT REGION 24..104
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 31..46
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 75..104
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1118 AA; 125680 MW; 09A7695CD8FDBB50 CRC64;
MADAQSDADK IRLKRIERLA ALAAKAPSDD AAPSSSPTSQ NGASKPADPA GTLKRIRPDS
QASVRTPAGS AKPTDAPVAS TSKLATSEPA IVQRPSESTT VSFPEPFDSW QSAALARILN
VTLDIATAEK SNWEIVYLKQ LRTELIEEDS RQRDPALYVV APSEQMTDGD SENGNAERAI
LARLALDPTD MSDDPEEITV LAGMSQISPF EYLVGAWQRS NEERAKIANG VRGKVFDPTE
TSKRLHVLER IRQLLISYIG LDLQETSIFV QPDGQDVGDI ELFNLMLNKH QSLRLTPGQL
TVLLGELAKR FEDDGLEDLI GAVARRLSLN MFQNRKVYSL GNMDAPGAWQ QSFAALRLLT
SNKTIASTFA SLPQFDPDAE PRFMQMTSLL GPFDQISVFP DDAPEVANEF FNNEEAADLE
DNETHDGQSG SLRRMLASVQ SELFSVYNDL IRSSPKAREN VLNHWAHIAN QNAKRSAIQQ
DKMRIASDGV MINLQTVLTQ FAEPFMDASY SKMDKIDIEY YLKCRRLDIR EETKINATQQ
EADDYYALAD GQPAPGANFI SDIFFLSAAY LHLGLMSALS QHKRSIKDYG RFKDHLAELR
EAAESHRSNA PLYARYQAAI EKLRHQMRGI SASQCQLHSP AFLNSQATFC NFMTVWLVRA
MDPQHKHPQT AITLPLPTEP PISFKMLPEY LVDDVTEFFT YVSRYRPDVM SQLRLDDLVT
FIIVVLSTPY VKNPFLKSKF VEILFYNTRR QTRRDGHDGV LGPIINTHPL ALSNLMGALI
HTYVEIESTG SHTQFYDKFN TRFYISLIFR VVWHNAEHRE ALKREAGDTK RFVRFCNLLL
NDTTFLLDES LGKFSLIKEL DKLMADSAAW SALTEEERKA KSKEKADYEG QAQSYLQLVY
ESVGLLRVFT EETTAPFVRG EIVDRLAAML DNNLDVLAGP RCKDLKIANA DKIKFRPREL
LADILQVIMN LSRRVEFATA VARDGRSYSR ELYYRAAGIA VRAALKTEQE MDELRKFVDQ
VEQIAADDRD DEAGEDVPEE FMDPLTYTIM RDPVLIPKSN NILDRTSISQ HLLSEATDPF
TRQPLTIEEC VPAVDLKSRI DAFLQAKRDA RALGHATT
//
