ID   G7GPN9_9ACTN            Unreviewed;       382 AA.
AC   G7GPN9;
DT   25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT   25-JAN-2012, sequence version 1.
DT   27-MAR-2024, entry version 43.
DE   SubName: Full=Geranylgeranyl pyrophosphate synthase {ECO:0000313|EMBL:GAB05564.1};
GN   Name=crtE {ECO:0000313|EMBL:GAB05564.1};
GN   ORFNames=GOAMR_40_00540 {ECO:0000313|EMBL:GAB05564.1};
OS   Gordonia amarae NBRC 15530.
OC   Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Gordoniaceae;
OC   Gordonia.
OX   NCBI_TaxID=1075090 {ECO:0000313|EMBL:GAB05564.1, ECO:0000313|Proteomes:UP000006023};
RN   [1] {ECO:0000313|EMBL:GAB05564.1, ECO:0000313|Proteomes:UP000006023}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NBRC 15530 {ECO:0000313|EMBL:GAB05564.1,
RC   ECO:0000313|Proteomes:UP000006023};
RA   Takarada H., Hosoyama A., Tsuchikane K., Katsumata H., Yamazaki S.,
RA   Fujita N.;
RT   "Whole genome shotgun sequence of Gordonia amarae NBRC 15530.";
RL   Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
CC   -!- PATHWAY: Isoprenoid biosynthesis. {ECO:0000256|ARBA:ARBA00005128}.
CC   -!- SIMILARITY: Belongs to the FPP/GGPP synthase family.
CC       {ECO:0000256|ARBA:ARBA00006706, ECO:0000256|RuleBase:RU004466}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:GAB05564.1}.
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DR   EMBL; BAED01000040; GAB05564.1; -; Genomic_DNA.
DR   RefSeq; WP_005186882.1; NZ_BAED01000040.1.
DR   AlphaFoldDB; G7GPN9; -.
DR   STRING; 1075090.GOAMR_40_00540; -.
DR   eggNOG; COG0142; Bacteria.
DR   Proteomes; UP000006023; Unassembled WGS sequence.
DR   GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008299; P:isoprenoid biosynthetic process; IEA:InterPro.
DR   CDD; cd00685; Trans_IPPS_HT; 1.
DR   Gene3D; 1.10.600.10; Farnesyl Diphosphate Synthase; 1.
DR   InterPro; IPR008949; Isoprenoid_synthase_dom_sf.
DR   InterPro; IPR000092; Polyprenyl_synt.
DR   InterPro; IPR033749; Polyprenyl_synt_CS.
DR   PANTHER; PTHR12001:SF88; (2E,6E)-FARNESYL DIPHOSPHATE SYNTHASE; 1.
DR   PANTHER; PTHR12001; GERANYLGERANYL PYROPHOSPHATE SYNTHASE; 1.
DR   Pfam; PF00348; polyprenyl_synt; 1.
DR   SFLD; SFLDS00005; Isoprenoid_Synthase_Type_I; 1.
DR   SFLD; SFLDG01017; Polyprenyl_Transferase_Like; 1.
DR   SUPFAM; SSF48576; Terpenoid synthases; 1.
DR   PROSITE; PS00723; POLYPRENYL_SYNTHASE_1; 1.
DR   PROSITE; PS00444; POLYPRENYL_SYNTHASE_2; 1.
PE   3: Inferred from homology;
KW   Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW   Reference proteome {ECO:0000313|Proteomes:UP000006023};
KW   Transferase {ECO:0000256|RuleBase:RU004466}.
SQ   SEQUENCE   382 AA;  40242 MW;  08385AE58CA54995 CRC64;
     MTSAHPVDQF AIPSGLDDVP AAVGGVLDDF FGRVFPHAAA IDPVVGEAAT MLREFTMNGG
     KRIRPTLVYA GWRCGVSERD RLRPGDGDNP AEALRAGAAI ELIQACALVH DDIIDRSDTR
     RGRPTIHREL ESTHADAGWS GSPAAFGVAG AILIGDLALS WADDLFHGVG VAEEMPAGPL
     RRGAARRAGA VWAAMRTEVL GGQILDVVNE SRGNESVSAA YRVMEFKTAA YTVARPLELG
     ATLAGGSVEL INALRSIGHD LGIAFQLRDD LLGVFGDPEQ TGKPSGDDLV AGKRTALIAV
     GLNRAGAAVG GELRGLIGRE LSAEELARAR EILVDVGAVA DMEQRIDHLG ERAQATITAL
     NTDDSVRAEL SALGHRLGHR QR
//