ID G7GS72_9ACTN Unreviewed; 490 AA.
AC G7GS72;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE SubName: Full=Hypoxanthine/guanine permease {ECO:0000313|EMBL:GAB06436.1};
GN Name=pbuG {ECO:0000313|EMBL:GAB06436.1};
GN ORFNames=GOAMR_52_00330 {ECO:0000313|EMBL:GAB06436.1};
OS Gordonia amarae NBRC 15530.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Gordoniaceae;
OC Gordonia.
OX NCBI_TaxID=1075090 {ECO:0000313|EMBL:GAB06436.1, ECO:0000313|Proteomes:UP000006023};
RN [1] {ECO:0000313|EMBL:GAB06436.1, ECO:0000313|Proteomes:UP000006023}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NBRC 15530 {ECO:0000313|EMBL:GAB06436.1,
RC ECO:0000313|Proteomes:UP000006023};
RA Takarada H., Hosoyama A., Tsuchikane K., Katsumata H., Yamazaki S.,
RA Fujita N.;
RT "Whole genome shotgun sequence of Gordonia amarae NBRC 15530.";
RL Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC
CC 2.A.40) family. Azg-like subfamily. {ECO:0000256|ARBA:ARBA00005697}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAB06436.1}.
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DR EMBL; BAED01000052; GAB06436.1; -; Genomic_DNA.
DR RefSeq; WP_005189439.1; NZ_BAED01000052.1.
DR AlphaFoldDB; G7GS72; -.
DR STRING; 1075090.GOAMR_52_00330; -.
DR eggNOG; COG2252; Bacteria.
DR Proteomes; UP000006023; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015205; F:nucleobase transmembrane transporter activity; IEA:InterPro.
DR GO; GO:1904823; P:purine nucleobase transmembrane transport; IEA:UniProt.
DR InterPro; IPR045018; Azg-like.
DR InterPro; IPR006043; NCS2.
DR PANTHER; PTHR43337; XANTHINE/URACIL PERMEASE C887.17-RELATED; 1.
DR PANTHER; PTHR43337:SF1; XANTHINE_URACIL PERMEASE C887.17-RELATED; 1.
DR Pfam; PF00860; Xan_ur_permease; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000006023};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 39..57
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 77..94
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 99..117
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 123..143
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 155..179
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 199..220
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 227..248
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 282..303
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 372..392
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 429..458
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 464..481
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 490 AA; 49893 MW; 0F48A1B33FE017E1 CRC64;
MADSSALDAP TPGGSGTGAL NRFFKISERG STLSREVRGG LVTFFTMAYI VVLNPIILGG
EHNTDANGHF LQLDQVAAVT ALVAGVMSII FGIVANYPFA LAAGLGINSL LAVTIAPQMS
WPAAMGLVVI DGIIIVVLAA TGFRTAVFNA VPTELKAAIA AGIGCFIAFV GLVDSGFVHR
VPDAANTTVP VQLGTEGNSI STVPTLIFVI GVLLMAVLVV WKVPGGLLLG IAIMTVVSII
VESVMGLGSG ATGKGGWSLS VPDIPDGVGG LPDLSLVGDV DLFGAFSQIS VFAACALVFA
LVLSNFFDAM GTMTGLGQEA GLADKDGALP GIGRALIVEG SGAVVGGAAS ASSNTVFVES
ASGIAEGART GLANVVTGGL FLVAMFLTPL YSIIPLEAVA PSLVVVGGMM ISQVRNIDFT
RFDVALPSFL TIVTMPFTYS IANGIGVGFI SWVVLAAASG KAKTVHPLLW LVAAVFVLYF
AREPISNLFD
//
