ID G7GSC3_9ACTN Unreviewed; 2212 AA.
AC G7GSC3;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 27-MAR-2024, entry version 59.
DE SubName: Full=Putative non-ribosomal peptide synthetase {ECO:0000313|EMBL:GAB06498.1};
GN ORFNames=GOAMR_54_00080 {ECO:0000313|EMBL:GAB06498.1};
OS Gordonia amarae NBRC 15530.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Gordoniaceae;
OC Gordonia.
OX NCBI_TaxID=1075090 {ECO:0000313|EMBL:GAB06498.1, ECO:0000313|Proteomes:UP000006023};
RN [1] {ECO:0000313|EMBL:GAB06498.1, ECO:0000313|Proteomes:UP000006023}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NBRC 15530 {ECO:0000313|EMBL:GAB06498.1,
RC ECO:0000313|Proteomes:UP000006023};
RA Takarada H., Hosoyama A., Tsuchikane K., Katsumata H., Yamazaki S.,
RA Fujita N.;
RT "Whole genome shotgun sequence of Gordonia amarae NBRC 15530.";
RL Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=pantetheine 4'-phosphate; Xref=ChEBI:CHEBI:47942;
CC Evidence={ECO:0000256|ARBA:ARBA00001957};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAB06498.1}.
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DR EMBL; BAED01000054; GAB06498.1; -; Genomic_DNA.
DR RefSeq; WP_005189643.1; NZ_BAED01000054.1.
DR STRING; 1075090.GOAMR_54_00080; -.
DR eggNOG; COG1020; Bacteria.
DR OrthoDB; 2472181at2; -.
DR UniPathway; UPA00011; -.
DR Proteomes; UP000006023; Unassembled WGS sequence.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
DR GO; GO:0043604; P:amide biosynthetic process; IEA:UniProt.
DR GO; GO:0008610; P:lipid biosynthetic process; IEA:UniProt.
DR GO; GO:1901566; P:organonitrogen compound biosynthetic process; IEA:UniProt.
DR GO; GO:0044550; P:secondary metabolite biosynthetic process; IEA:UniProt.
DR CDD; cd05930; A_NRPS; 1.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.980; -; 2.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR Gene3D; 3.30.559.10; Chloramphenicol acetyltransferase-like domain; 3.
DR Gene3D; 3.30.559.30; Nonribosomal peptide synthetase, condensation domain; 3.
DR InterPro; IPR010071; AA_adenyl_domain.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR036736; ACP-like_sf.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR023213; CAT-like_dom_sf.
DR InterPro; IPR001242; Condensatn.
DR InterPro; IPR020806; PKS_PP-bd.
DR InterPro; IPR009081; PP-bd_ACP.
DR InterPro; IPR001031; Thioesterase.
DR NCBIfam; TIGR01733; AA-adenyl-dom; 1.
DR PANTHER; PTHR45527:SF1; FATTY ACID SYNTHASE; 1.
DR PANTHER; PTHR45527; NONRIBOSOMAL PEPTIDE SYNTHETASE; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR Pfam; PF00668; Condensation; 2.
DR Pfam; PF00550; PP-binding; 1.
DR Pfam; PF00975; Thioesterase; 1.
DR SMART; SM00823; PKS_PP; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR SUPFAM; SSF47336; ACP-like; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR SUPFAM; SSF52777; CoA-dependent acyltransferases; 5.
DR PROSITE; PS00455; AMP_BINDING; 1.
DR PROSITE; PS50075; CARRIER; 1.
PE 4: Predicted;
KW Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000006023}.
FT DOMAIN 1870..1945
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
SQ SEQUENCE 2212 AA; 234545 MW; 77ACC5EA130C990F CRC64;
MTDSTTITVP APEASARPLT AAQREIWVGQ RLTDDATAYS TVLVAHARGP VDFDVLLAAM
RAAMAESQAV RVRFRVSDGG EVVQEPTDTV PAVDIVDLRG RADAYAQARE WISAELERPY
EVTGRPGDGN NGLGEILFRI NLIRVEDEYT LAFLSAHHLI LDGTAVGFVL ASGLSRYERM
CRGEVSAGAD DSGEQWSLSS LVDLDEDYRN SEQFTRDRDF WLAHVADAPP PPRLLTDLDP
IPRRADILAV GLSDNEYDRL YGLARTLGVR TAGLLFAALA GFLHRRTGQS DLMLAMPMAA
RTTPELRTHL GTFATVLPVR VRLRSGATWR QAAGDIDELL GEVAPHSRFR GEDLGRALRE
AGTPKALFGV GANVLPLSTR PFSRLGIDAT LEILSSGPTG DIDVFFEVDV PAKKIRLNLH
GPGTHMAEMT RIADELAEYV RGLINDPEQV IGPRLVAGPG PAATAAQAPA GTLPGAEEWI
AAGESESFGD APQNDAPDAP VIALQTPPGT EAAQVRAILA ALVGAHPELS LRAQEWAPGL
WEYVPADTPA ELTILAAAAS PDQAVDELPY TAGGFGATWI PGVRRKPGTL LLAAHPLIVD
AHGLQILRRD VDACWAAIAS GGAISLAPTP APADAVTWAG DRAQTGACIE QLDGWLELCR
QAPAVEPGDG RSTATAEAVT DPAAATAAGL DPSGAALASL ALALHDIGSA TGGSEIVIDL
DRTGRTGYPE PVGGSAAPFG FAAPLAVPVS ADPATALRSA RTCLNRQRDN GLDFALLRYL
HPQASGVLAG AGERWQVRVR DERGLLRIRG SEPETGALVR VTEAGYEFTV YSPLPAGDRL
IEPRQLAAAW AHAAQSVATA AADPANQVGP SPDNIVGVAL SDTARTRLRQ LAPGTIEAIW
ALSPLQEGLY FQSVVSEDLD IYNAQFVLEF DRALDPDRLR HALTALMADH PALRGGFTHA
GLPGPVQYVV DRLPAPLEIA DLRELRGAAL DEAYDEVILA DRAHKFELAA PPLWRVTLIR
RPDGDRLAVS RRFLVWDGWS NGSFIGGLLA HYAGDTDSAP APIESAVFAR YLRWLGDRDR
DAAVAAWADY LDGYDEPSVL VPEADPVVRG YTRIHQHTLS AEQSAALPAL ARDAGVTLNT
VLSTALLLVV SRWTGRTDVA IGQTVAGRPP EVEGTDAAIG MFLNTVPVRA RLRPEATVAD
LLTAQQSTAL GVLGHDWLSL GEIQAQASAP VLFDTLLVLQ NFISDALLGA EHGVVGHTSD
DHTHFALTVV ITPGDELTVK IETRSDIVDD ETADGLSGDL ITVLTALAAP GDVFGTPLAR
LPIAAVEAPQ TGRTLDVPDL SVSELLAATA ADNADDTALI CGDRSLTFGE LDAEINRLAR
LLLAEGAAPE TVVALGIERS IEMVVALFAV LRTGAAYLPL ELVHPAERLH ELVADARPVL
ALTAGTTADT DRVIFGGTGA APIDLRSGRI RERLAALSPE PLSDSELGGF ASDHADRLDH
PAYVIYTSGS TGTPKGVVTG YRGLTNMYVN HLDEIFRPAV ARSRFDRLHI AHTVSFAFDM
SWEELLWLTY GHTVHVCDEE LRRDPRELVA YCDTHRIDVI NVTPTYAEYL IAAGLLDGDS
FGGPTGAHRP ALVLLGGEAV GTGVWDALRD ADGTEGYNLY GPTEYTINTL GGGTEDSATP
TVGRPISNTV GYLLDPWLRP VPPGVPGELY VEGDGLARGY GGRPDLTAAS FVAHPAHPGE
RLYRTGDLMR RRADGLLDYL GRTDFQIKVR GYRVEPAEVE AVLAAVDGVL HAAVVARTDT
TGSTALAGYV VSDGALPPIP QIRRQLAERL PAYMVPSTIT EIDEIPVNVN GKRDTSALPE
PVAAGGGSGR SGSMLERVLA EIAAGVFGVD EVDPDTNLFD LGAHSLQLMT FADAVRGRLG
VELKVADVFT NPTIAGMAAV LGGDSDTGSH LRVPVITFRS GTDAGTPVFI LPPGTGLGWR
YGQLLAHIPD SCGVFAVQSP AIAGIEVPAD LASAAQYFAE QIDLAAPAAD DGVKPPVTLL
GWSFGGSVTT TVVAALAGRG RPVGSLVLVD AFARSPEEYF DYVDTIAPAA AALAAIDVPV
PAELAAGLTV EQAVEVVRGS ESVFAGLGAD YIESIVESNM WALTVMRELH PPTAPIDTPV
LYVEADPPFS FNTWSGMLNM KQHVQTEYSH PQMLNPDAVR TWGPRLADFL ER
//
