ID G7GSD4_9ACTN Unreviewed; 526 AA.
AC G7GSD4;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 24-JAN-2024, entry version 35.
DE RecName: Full=UmuC domain-containing protein {ECO:0000259|PROSITE:PS50173};
GN ORFNames=GOAMR_54_00190 {ECO:0000313|EMBL:GAB06509.1};
OS Gordonia amarae NBRC 15530.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Gordoniaceae;
OC Gordonia.
OX NCBI_TaxID=1075090 {ECO:0000313|EMBL:GAB06509.1, ECO:0000313|Proteomes:UP000006023};
RN [1] {ECO:0000313|EMBL:GAB06509.1, ECO:0000313|Proteomes:UP000006023}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NBRC 15530 {ECO:0000313|EMBL:GAB06509.1,
RC ECO:0000313|Proteomes:UP000006023};
RA Takarada H., Hosoyama A., Tsuchikane K., Katsumata H., Yamazaki S.,
RA Fujita N.;
RT "Whole genome shotgun sequence of Gordonia amarae NBRC 15530.";
RL Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Poorly processive, error-prone DNA polymerase involved in
CC untargeted mutagenesis. Copies undamaged DNA at stalled replication
CC forks, which arise in vivo from mismatched or misaligned primer ends.
CC These misaligned primers can be extended by PolIV. Exhibits no 3'-5'
CC exonuclease (proofreading) activity. May be involved in translesional
CC synthesis, in conjunction with the beta clamp from PolIII.
CC {ECO:0000256|ARBA:ARBA00025589}.
CC -!- SIMILARITY: Belongs to the DNA polymerase type-Y family.
CC {ECO:0000256|ARBA:ARBA00010945}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAB06509.1}.
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DR EMBL; BAED01000054; GAB06509.1; -; Genomic_DNA.
DR RefSeq; WP_005189665.1; NZ_BAED01000054.1.
DR AlphaFoldDB; G7GSD4; -.
DR STRING; 1075090.GOAMR_54_00190; -.
DR eggNOG; COG0389; Bacteria.
DR OrthoDB; 5244088at2; -.
DR Proteomes; UP000006023; Unassembled WGS sequence.
DR GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR CDD; cd03468; PolY_like; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.40.1170.60; -; 1.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR InterPro; IPR001126; UmuC.
DR PANTHER; PTHR35369:SF2; BLR3025 PROTEIN; 1.
DR PANTHER; PTHR35369; BLR3025 PROTEIN-RELATED; 1.
DR Pfam; PF00817; IMS; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR PROSITE; PS50173; UMUC; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000006023}.
FT DOMAIN 28..109
FT /note="UmuC"
FT /evidence="ECO:0000259|PROSITE:PS50173"
SQ SEQUENCE 526 AA; 56386 MW; 8BA71DD192FD5FA3 CRC64;
MSAQRVLALW CPDWPASAAA ADSNLAPDVP VAVLHANRVV ACSASARRSG VRRGMRKRQA
QAACPEMVLA GADADRDGQQ YEPIVAAVME VVPVVEVLRP GLLVIPLTMS LCRHLGDEQV
IAERLTDVVG SCGAEALAGI ADEMFTAVLA ARRGQCVEPG GDAAWLAPLP VAELAVEPCF
GGPERAELVD LLRRLGITTI GVFAGFPIRD VATRFNADAV AAHRLANAAP ARGPVGGRIE
EDLVIEYDCD PQIDRVDAAA FVGRRLADEL HRRLAAVSMS CTRLTVEAVT ELGQRHSRTW
RAVTPLTADD MACRIRWQLD GWLTGGRTTR DHRTDVRRPD SPIALLRIDP VEVIDSGTLH
YTLSGYGLPE SEMDSERART ALARVQGLLG GDAVKIPVLS GGRGPADRIR LVTLGEDPVP
QGDPLAPWPG RLPQPAPATM TEVAVAVLDP EGDPVRVSAR GAFSAEPALV VGSRKWSVRW
WAGPWPTGLD ADGTEVSARA QILLDDSRAL LLHYREGSWT IEGIYE
//
