ID G7IEA4_MEDTR Unreviewed; 1159 AA.
AC G7IEA4;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 27-MAR-2024, entry version 75.
DE SubName: Full=P-loop nucleoside triphosphate hydrolase superfamily protein {ECO:0000313|EMBL:AES62989.1};
GN OrderedLocusNames=MTR_1g114540 {ECO:0000313|EMBL:AES62989.1};
OS Medicago truncatula (Barrel medic) (Medicago tribuloides).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; Hologalegina; IRL clade; Trifolieae; Medicago.
OX NCBI_TaxID=3880 {ECO:0000313|EMBL:AES62989.1, ECO:0000313|Proteomes:UP000002051};
RN [1] {ECO:0000313|EMBL:AES62989.1, ECO:0000313|Proteomes:UP000002051}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=A17 {ECO:0000313|EMBL:AES62989.1}, and cv. Jemalong A17
RC {ECO:0000313|EnsemblPlants:AES62989,
RC ECO:0000313|Proteomes:UP000002051};
RX PubMed=22089132; DOI=10.1038/nature10625;
RA Young N.D., Debelle F., Oldroyd G.E., Geurts R., Cannon S.B., Udvardi M.K.,
RA Benedito V.A., Mayer K.F., Gouzy J., Schoof H., Van de Peer Y., Proost S.,
RA Cook D.R., Meyers B.C., Spannagl M., Cheung F., De Mita S.,
RA Krishnakumar V., Gundlach H., Zhou S., Mudge J., Bharti A.K., Murray J.D.,
RA Naoumkina M.A., Rosen B., Silverstein K.A., Tang H., Rombauts S.,
RA Zhao P.X., Zhou P., Barbe V., Bardou P., Bechner M., Bellec A., Berger A.,
RA Berges H., Bidwell S., Bisseling T., Choisne N., Couloux A., Denny R.,
RA Deshpande S., Dai X., Doyle J.J., Dudez A.M., Farmer A.D., Fouteau S.,
RA Franken C., Gibelin C., Gish J., Goldstein S., Gonzalez A.J., Green P.J.,
RA Hallab A., Hartog M., Hua A., Humphray S.J., Jeong D.H., Jing Y.,
RA Jocker A., Kenton S.M., Kim D.J., Klee K., Lai H., Lang C., Lin S.,
RA Macmil S.L., Magdelenat G., Matthews L., McCorrison J., Monaghan E.L.,
RA Mun J.H., Najar F.Z., Nicholson C., Noirot C., O'Bleness M., Paule C.R.,
RA Poulain J., Prion F., Qin B., Qu C., Retzel E.F., Riddle C., Sallet E.,
RA Samain S., Samson N., Sanders I., Saurat O., Scarpelli C., Schiex T.,
RA Segurens B., Severin A.J., Sherrier D.J., Shi R., Sims S., Singer S.R.,
RA Sinharoy S., Sterck L., Viollet A., Wang B.B., Wang K., Wang M., Wang X.,
RA Warfsmann J., Weissenbach J., White D.D., White J.D., Wiley G.B.,
RA Wincker P., Xing Y., Yang L., Yao Z., Ying F., Zhai J., Zhou L., Zuber A.,
RA Denarie J., Dixon R.A., May G.D., Schwartz D.C., Rogers J., Quetier F.,
RA Town C.D., Roe B.A.;
RT "The Medicago genome provides insight into the evolution of rhizobial
RT symbioses.";
RL Nature 480:520-524(2011).
RN [2] {ECO:0000313|EMBL:AES62989.1, ECO:0000313|Proteomes:UP000002051}
RP GENOME REANNOTATION.
RC STRAIN=A17 {ECO:0000313|EMBL:AES62989.1}, and cv. Jemalong A17
RC {ECO:0000313|EnsemblPlants:AES62989,
RC ECO:0000313|Proteomes:UP000002051};
RX PubMed=24767513; DOI=10.1186/1471-2164-15-312;
RA Tang H., Krishnakumar V., Bidwell S., Rosen B., Chan A., Zhou S.,
RA Gentzbittel L., Childs K.L., Yandell M., Gundlach H., Mayer K.F.,
RA Schwartz D.C., Town C.D.;
RT "An improved genome release (version Mt4.0) for the model legume Medicago
RT truncatula.";
RL BMC Genomics 15:312-312(2014).
RN [3] {ECO:0000313|EnsemblPlants:AES62989}
RP IDENTIFICATION.
RC STRAIN=cv. Jemalong A17 {ECO:0000313|EnsemblPlants:AES62989};
RG EnsemblPlants;
RL Submitted (APR-2015) to UniProtKB.
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Myosin family. {ECO:0000256|PROSITE-ProRule:PRU00782}.
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DR EMBL; CM001217; AES62989.1; -; Genomic_DNA.
DR RefSeq; XP_003592738.1; XM_003592690.2.
DR AlphaFoldDB; G7IEA4; -.
DR STRING; 3880.G7IEA4; -.
DR PaxDb; 3880-AES62989; -.
DR EnsemblPlants; AES62989; AES62989; MTR_1g114540.
DR Gramene; AES62989; AES62989; MTR_1g114540.
DR eggNOG; KOG0160; Eukaryota.
DR HOGENOM; CLU_000192_7_2_1; -.
DR OMA; PHSYRYL; -.
DR Proteomes; UP000002051; Chromosome 1.
DR GO; GO:0015629; C:actin cytoskeleton; IBA:GO_Central.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
DR GO; GO:0031982; C:vesicle; IBA:GO_Central.
DR GO; GO:0051015; F:actin filament binding; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0000146; F:microfilament motor activity; IBA:GO_Central.
DR GO; GO:0007015; P:actin filament organization; IBA:GO_Central.
DR GO; GO:0030050; P:vesicle transport along actin filament; IBA:GO_Central.
DR CDD; cd01383; MYSc_Myo8; 1.
DR Gene3D; 1.10.10.820; -; 1.
DR Gene3D; 1.20.5.190; -; 2.
DR Gene3D; 1.20.58.530; -; 1.
DR Gene3D; 6.20.240.20; -; 1.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR Gene3D; 1.20.120.720; Myosin VI head, motor domain, U50 subdomain; 1.
DR InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR001609; Myosin_head_motor_dom.
DR InterPro; IPR004009; Myosin_N.
DR InterPro; IPR036022; MYSc_Myo8.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR13140; MYOSIN; 1.
DR PANTHER; PTHR13140:SF780; MYOSIN-1; 1.
DR Pfam; PF00612; IQ; 3.
DR Pfam; PF00063; Myosin_head; 1.
DR PRINTS; PR00193; MYOSINHEAVY.
DR SMART; SM00015; IQ; 4.
DR SMART; SM00242; MYSc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50096; IQ; 3.
DR PROSITE; PS51456; MYOSIN_MOTOR; 1.
DR PROSITE; PS51844; SH3_LIKE; 1.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; Calmodulin-binding {ECO:0000256|ARBA:ARBA00022860};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Hydrolase {ECO:0000313|EMBL:AES62989.1};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Myosin {ECO:0000256|ARBA:ARBA00023123, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; Reference proteome {ECO:0000313|Proteomes:UP000002051}.
FT DOMAIN 126..175
FT /note="Myosin N-terminal SH3-like"
FT /evidence="ECO:0000259|PROSITE:PS51844"
FT DOMAIN 179..834
FT /note="Myosin motor"
FT /evidence="ECO:0000259|PROSITE:PS51456"
FT REGION 1..121
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 714..736
FT /note="Actin-binding"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
FT REGION 1021..1061
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 954..1002
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 93..121
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1021..1035
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 270..277
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
SQ SEQUENCE 1159 AA; 131073 MW; 981973FCBFED6D0C CRC64;
MSQTTGVPPA FQSIKSLPPE FKFDSNRNTG LVEKHGNAKV RSTDLIGSNG RKNGAIVGEV
SKEVHNRAGG MDVSDEESPY GGNGESFEDR PSYPNEDSVS ASLPQPSIST PSGESRWSDT
TPYASKKKLQ SWLQLSNGDW ELVKIISTSG TESVISLPDG KVLKVKDEDL VPANPDILDG
VDDLMQLSYL NEPSVLYNLQ HRYNQNMIYT KAGPVLVAVN PFKKVPLYGT NYIEAYKRKA
IESPHVYAIT DSAIREMIRD EVNQSIIISG ESGAGKTETA KIAMQYLAAL GGGSGIEHEI
LKTNPILEAF GNGKTLRNDN SSRFGKLIEI HFSETGKISG ANIQTFLLEK SRVVQCNEGE
RSYHIFYQLC AGAPSSLREK LNLRSVEDYK YLRQSNCYSI NDVDDAEEFR IVTDALDVVH
ISKEDQENVF AMLAAVLWLG NISFTVIDNE NHVQAVEDEG LFSTAKLIVG KDTIVQKLTL
SQASDARDAL AKSIYSCLFD WLVEQINKSL AVGKRQTGRS ISILDIYGFE SFNRNSFEQF
CINYANERLQ QHFNRHLFKL EQEEYIQDGI DWAKVEFEDN QDCLNLFEKK PLGLLSLLDE
ESTFPNGTDL TFANKLKQHL NSNSCFKEER EKAFTVRHYA GEVTYDTTAF LEKNRDLMHV
DSIQLLSSSK CHLPQIFASY MLSQSEKPVV GPLHKLGGAD SQKLSVATKF KGQLFQLMQR
LESTTPHFIR CIKPNNLQSP GSYEQGLVLQ QLRCCGVLEV VRISRSGFPT RMSHQKFAKR
YGFLLLENVA SQDPLSVSVA ILHQFNILPE MYQVGYTKLF FRTGQIGVLE DTRNRTLHGI
LRVQSCFRGY QARCHCKELW RGITTLQSFI RGEKSRKEFA TLLQRHRAAV IIQKHVKTVY
QSKRMKDTID SAVVIQSFIR GWLVRRCSGD IGFLKSGGMK TNESDEVLVK ASFLAELQRR
VLKAEAGLRE KDEENDILHQ RLQQYESRWS EYELKMKSME EVWQKQMRSL QSSLSIAKKS
LAMDDSERNS DASVNASDDK EYSWDMGNNH RRQESSGTRS MSAGLSVISR LAEEFEQRSQ
VFGDDAKFLV EVKSGQIEAS LNPDRELRRL KQMFEGWKKD YAARLRETKV ILNKLGSEDG
SIEKAKKKWW GRRNSTRMS
//
