ID G7IIF8_MEDTR Unreviewed; 1080 AA.
AC G7IIF8; A0A0C3V211;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2014, sequence version 2.
DT 27-MAR-2024, entry version 56.
DE SubName: Full=LRR and NB-ARC domain disease resistance protein {ECO:0000313|EMBL:AES65401.2};
GN OrderedLocusNames=MTR_2g038930 {ECO:0000313|EMBL:AES65401.2};
OS Medicago truncatula (Barrel medic) (Medicago tribuloides).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; Hologalegina; IRL clade; Trifolieae; Medicago.
OX NCBI_TaxID=3880 {ECO:0000313|EMBL:AES65401.2, ECO:0000313|Proteomes:UP000002051};
RN [1] {ECO:0000313|EMBL:AES65401.2, ECO:0000313|Proteomes:UP000002051}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=A17 {ECO:0000313|EMBL:AES65401.2}, and cv. Jemalong A17
RC {ECO:0000313|EnsemblPlants:AES65401,
RC ECO:0000313|Proteomes:UP000002051};
RX PubMed=22089132; DOI=10.1038/nature10625;
RA Young N.D., Debelle F., Oldroyd G.E., Geurts R., Cannon S.B., Udvardi M.K.,
RA Benedito V.A., Mayer K.F., Gouzy J., Schoof H., Van de Peer Y., Proost S.,
RA Cook D.R., Meyers B.C., Spannagl M., Cheung F., De Mita S.,
RA Krishnakumar V., Gundlach H., Zhou S., Mudge J., Bharti A.K., Murray J.D.,
RA Naoumkina M.A., Rosen B., Silverstein K.A., Tang H., Rombauts S.,
RA Zhao P.X., Zhou P., Barbe V., Bardou P., Bechner M., Bellec A., Berger A.,
RA Berges H., Bidwell S., Bisseling T., Choisne N., Couloux A., Denny R.,
RA Deshpande S., Dai X., Doyle J.J., Dudez A.M., Farmer A.D., Fouteau S.,
RA Franken C., Gibelin C., Gish J., Goldstein S., Gonzalez A.J., Green P.J.,
RA Hallab A., Hartog M., Hua A., Humphray S.J., Jeong D.H., Jing Y.,
RA Jocker A., Kenton S.M., Kim D.J., Klee K., Lai H., Lang C., Lin S.,
RA Macmil S.L., Magdelenat G., Matthews L., McCorrison J., Monaghan E.L.,
RA Mun J.H., Najar F.Z., Nicholson C., Noirot C., O'Bleness M., Paule C.R.,
RA Poulain J., Prion F., Qin B., Qu C., Retzel E.F., Riddle C., Sallet E.,
RA Samain S., Samson N., Sanders I., Saurat O., Scarpelli C., Schiex T.,
RA Segurens B., Severin A.J., Sherrier D.J., Shi R., Sims S., Singer S.R.,
RA Sinharoy S., Sterck L., Viollet A., Wang B.B., Wang K., Wang M., Wang X.,
RA Warfsmann J., Weissenbach J., White D.D., White J.D., Wiley G.B.,
RA Wincker P., Xing Y., Yang L., Yao Z., Ying F., Zhai J., Zhou L., Zuber A.,
RA Denarie J., Dixon R.A., May G.D., Schwartz D.C., Rogers J., Quetier F.,
RA Town C.D., Roe B.A.;
RT "The Medicago genome provides insight into the evolution of rhizobial
RT symbioses.";
RL Nature 480:520-524(2011).
RN [2] {ECO:0000313|EMBL:AES65401.2, ECO:0000313|Proteomes:UP000002051}
RP GENOME REANNOTATION.
RC STRAIN=cv. Jemalong A17 {ECO:0000313|EnsemblPlants:AES65401,
RC ECO:0000313|Proteomes:UP000002051};
RX PubMed=24767513; DOI=10.1186/1471-2164-15-312;
RA Tang H., Krishnakumar V., Bidwell S., Rosen B., Chan A., Zhou S.,
RA Gentzbittel L., Childs K.L., Yandell M., Gundlach H., Mayer K.F.,
RA Schwartz D.C., Town C.D.;
RT "An improved genome release (version Mt4.0) for the model legume Medicago
RT truncatula.";
RL BMC Genomics 15:312-312(2014).
RN [3] {ECO:0000313|EnsemblPlants:AES65401}
RP IDENTIFICATION.
RC STRAIN=cv. Jemalong A17 {ECO:0000313|EnsemblPlants:AES65401};
RG EnsemblPlants;
RL Submitted (APR-2015) to UniProtKB.
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DR EMBL; CM001218; AES65401.2; -; Genomic_DNA.
DR RefSeq; XP_003595150.2; XM_003595102.2.
DR AlphaFoldDB; G7IIF8; -.
DR PaxDb; 3880-AES65401; -.
DR EnsemblPlants; AES65401; AES65401; MTR_2g038930.
DR Gramene; AES65401; AES65401; MTR_2g038930.
DR eggNOG; KOG4658; Eukaryota.
DR HOGENOM; CLU_000837_8_8_1; -.
DR Proteomes; UP000002051; Chromosome 2.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0006952; P:defense response; IEA:UniProtKB-KW.
DR GO; GO:0051707; P:response to other organism; IEA:UniProt.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR044974; Disease_R_plants.
DR InterPro; IPR006553; Leu-rich_rpt_Cys-con_subtyp.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR23155; DISEASE RESISTANCE PROTEIN RP; 1.
DR PANTHER; PTHR23155:SF1235; DISEASE RESISTANCE RPP13-LIKE PROTEIN 1; 1.
DR Pfam; PF00931; NB-ARC; 1.
DR PRINTS; PR00364; DISEASERSIST.
DR SMART; SM00367; LRR_CC; 3.
DR SMART; SM00369; LRR_TYP; 3.
DR SUPFAM; SSF52058; L domain-like; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 4: Predicted;
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Plant defense {ECO:0000256|ARBA:ARBA00022821};
KW Reference proteome {ECO:0000313|Proteomes:UP000002051};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 13..233
FT /note="NB-ARC"
FT /evidence="ECO:0000259|Pfam:PF00931"
SQ SEQUENCE 1080 AA; 123366 MW; 49C6D6A8ACB8BE50 CRC64;
MNSPMYGRND DQTTLSNWLK SQDKKLSVIS MVGMGGIGKT TLAQHLYNDP MIVERFHVRA
WVNMSQDFDV CRITRVILES IAGSVKETTN QSILQEKLKE QLIGKKFFIV LDSVWIQDRM
KWRRFKTPFT YRAQGSKILV TTRGGEVASV TTSDQIHQLH HLDEEDSWTL FAKHAFHGFD
DSYAVSWTKK TTLHEKVGKK VADKCKGLPL ALIAIGNLLR RNSSLRHWEK ISESDAWDLA
EGTRIVPALM VSYQSLPTHL KKCFEYCALF PKGYLYEKDQ LCLLWMAENL IQRPRQHMTS
MKEVAESYFN DLILRSFFQP STKYRNYFVM HDLHHDLSKS IFGEFCFTWE GRKSKNMTSI
TRHFSFLCDE IGSPKGLETL FDAKKLRTFL PLSMTCFEYQ WLLCFNSNKL LLSELFSKCK
RLRVLSLCGC MDMIELPDNI GNLKHLHHLD LSRTKISKLP DTLCSLHYLQ TLKVRDCQFL
EELPMNLHKL VNLCYLDFSG TKVTVMPKEM GKLKNLEVLS SFYVGKGNDS SIQQLGDLNL
HGNLVVADLE NVMNPEDSVS ANLERKINLL KLELRWNATR NSSQKEREVL QNLKPSIHLN
ELSIEKYCGT LFPHWFGDNS LSRLVSLKLS NCENCILLPS LGVMSSLKHL RITGLSGIVV
IGMEFYRDGR SSTVSIPFPS LETLTFKDMN GWEKWEFEVV KGVVFPRLKK LSIMRCPNLK
DKLPETLECL VSLKICDCKQ LVTSVPFSPS ISELRLTNCG KLKFNYHLST LKFLYIRQCY
IEGSSVDWIR HTLSECGTNI KSLKIEDCAT MHIPLCGCYN FLVKLDITSS CDSLTTFPLN
LFPNLDFLDL YKCSSFEMIS QENEHLKLTS LSIGECPKFA SFPKGGLSTP RLQHFDISKL
ENLKSLPKCM HVLLPSLYKL SIDNCPQLES FSDGGLPSSL RNLFLVKCSK LLINSLKCAL
STNTSLFTMY IQEADVESFP NQGLLPLSLT YLNIRGCRNL KQLDYKGLEN LPSLRTLSLN
NCPNIQCLPK EGLPKSISTL QILGNCSLLK QRCKKPNGED YRKIAQIECV MIDNYTSSDV
//
