ID G7J9Q4_MEDTR Unreviewed; 1249 AA.
AC G7J9Q4; A0A0C3VMU9;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2014, sequence version 2.
DT 27-MAR-2024, entry version 74.
DE SubName: Full=ABC transporter B family protein {ECO:0000313|EMBL:AES72696.2};
GN Name=11440460 {ECO:0000313|EnsemblPlants:AES72696};
GN OrderedLocusNames=MTR_3g093430 {ECO:0000313|EMBL:AES72696.2};
OS Medicago truncatula (Barrel medic) (Medicago tribuloides).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; Hologalegina; IRL clade; Trifolieae; Medicago.
OX NCBI_TaxID=3880 {ECO:0000313|EMBL:AES72696.2, ECO:0000313|Proteomes:UP000002051};
RN [1] {ECO:0000313|EMBL:AES72696.2, ECO:0000313|Proteomes:UP000002051}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=A17 {ECO:0000313|EMBL:AES72696.2}, and cv. Jemalong A17
RC {ECO:0000313|EnsemblPlants:AES72696,
RC ECO:0000313|Proteomes:UP000002051};
RX PubMed=22089132; DOI=10.1038/nature10625;
RA Young N.D., Debelle F., Oldroyd G.E., Geurts R., Cannon S.B., Udvardi M.K.,
RA Benedito V.A., Mayer K.F., Gouzy J., Schoof H., Van de Peer Y., Proost S.,
RA Cook D.R., Meyers B.C., Spannagl M., Cheung F., De Mita S.,
RA Krishnakumar V., Gundlach H., Zhou S., Mudge J., Bharti A.K., Murray J.D.,
RA Naoumkina M.A., Rosen B., Silverstein K.A., Tang H., Rombauts S.,
RA Zhao P.X., Zhou P., Barbe V., Bardou P., Bechner M., Bellec A., Berger A.,
RA Berges H., Bidwell S., Bisseling T., Choisne N., Couloux A., Denny R.,
RA Deshpande S., Dai X., Doyle J.J., Dudez A.M., Farmer A.D., Fouteau S.,
RA Franken C., Gibelin C., Gish J., Goldstein S., Gonzalez A.J., Green P.J.,
RA Hallab A., Hartog M., Hua A., Humphray S.J., Jeong D.H., Jing Y.,
RA Jocker A., Kenton S.M., Kim D.J., Klee K., Lai H., Lang C., Lin S.,
RA Macmil S.L., Magdelenat G., Matthews L., McCorrison J., Monaghan E.L.,
RA Mun J.H., Najar F.Z., Nicholson C., Noirot C., O'Bleness M., Paule C.R.,
RA Poulain J., Prion F., Qin B., Qu C., Retzel E.F., Riddle C., Sallet E.,
RA Samain S., Samson N., Sanders I., Saurat O., Scarpelli C., Schiex T.,
RA Segurens B., Severin A.J., Sherrier D.J., Shi R., Sims S., Singer S.R.,
RA Sinharoy S., Sterck L., Viollet A., Wang B.B., Wang K., Wang M., Wang X.,
RA Warfsmann J., Weissenbach J., White D.D., White J.D., Wiley G.B.,
RA Wincker P., Xing Y., Yang L., Yao Z., Ying F., Zhai J., Zhou L., Zuber A.,
RA Denarie J., Dixon R.A., May G.D., Schwartz D.C., Rogers J., Quetier F.,
RA Town C.D., Roe B.A.;
RT "The Medicago genome provides insight into the evolution of rhizobial
RT symbioses.";
RL Nature 480:520-524(2011).
RN [2] {ECO:0000313|EMBL:AES72696.2, ECO:0000313|Proteomes:UP000002051}
RP GENOME REANNOTATION.
RC STRAIN=cv. Jemalong A17 {ECO:0000313|EnsemblPlants:AES72696,
RC ECO:0000313|Proteomes:UP000002051};
RX PubMed=24767513; DOI=10.1186/1471-2164-15-312;
RA Tang H., Krishnakumar V., Bidwell S., Rosen B., Chan A., Zhou S.,
RA Gentzbittel L., Childs K.L., Yandell M., Gundlach H., Mayer K.F.,
RA Schwartz D.C., Town C.D.;
RT "An improved genome release (version Mt4.0) for the model legume Medicago
RT truncatula.";
RL BMC Genomics 15:312-312(2014).
RN [3] {ECO:0000313|EnsemblPlants:AES72696}
RP IDENTIFICATION.
RC STRAIN=cv. Jemalong A17 {ECO:0000313|EnsemblPlants:AES72696};
RG EnsemblPlants;
RL Submitted (APR-2015) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CM001219; AES72696.2; -; Genomic_DNA.
DR RefSeq; XP_003602445.2; XM_003602397.2.
DR AlphaFoldDB; G7J9Q4; -.
DR STRING; 3880.G7J9Q4; -.
DR PaxDb; 3880-AES72696; -.
DR EnsemblPlants; AES72696; AES72696; MTR_3g093430.
DR GeneID; 11440460; -.
DR Gramene; AES72696; AES72696; MTR_3g093430.
DR KEGG; mtr:11440460; -.
DR HOGENOM; CLU_000604_17_2_1; -.
DR OrthoDB; 5487044at2759; -.
DR Proteomes; UP000002051; Chromosome 3.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0042626; F:ATPase-coupled transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0055085; P:transmembrane transport; IBA:GO_Central.
DR CDD; cd18577; ABC_6TM_Pgp_ABCB1_D1_like; 1.
DR CDD; cd18578; ABC_6TM_Pgp_ABCB1_D2_like; 1.
DR CDD; cd03249; ABC_MTABC3_MDL1_MDL2; 2.
DR Gene3D; 1.20.1560.10; ABC transporter type 1, transmembrane domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR011527; ABC1_TM_dom.
DR InterPro; IPR036640; ABC1_TM_sf.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR039421; Type_1_exporter.
DR PANTHER; PTHR24222:SF84; ABC TRANSMEMBRANE TYPE-1 DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR24222; ABC TRANSPORTER B FAMILY; 1.
DR Pfam; PF00664; ABC_membrane; 2.
DR Pfam; PF00005; ABC_tran; 2.
DR SMART; SM00382; AAA; 2.
DR SUPFAM; SSF90123; ABC transporter transmembrane region; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS50929; ABC_TM1F; 2.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 2.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000002051};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 38..62
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 89..111
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 173..201
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 278..298
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 304..322
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 674..699
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 719..742
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 795..815
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 900..921
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 43..330
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000259|PROSITE:PS50929"
FT DOMAIN 364..600
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT DOMAIN 678..962
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000259|PROSITE:PS50929"
FT DOMAIN 997..1241
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT REGION 605..636
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 610..636
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1249 AA; 137884 MW; 609B58A113803812 CRC64;
MADITEEENG HDDDEMKKNV VRALPFFKLL SYADYVDWIL MGLGTLGSIV HGMALPVGYL
LLGKALNAFG NNINNIDAMV PALKKVVPFV WYMAIATFPA GVLEIGCWMY ASERQLSRLR
LAYLKAVLSQ EIGAFDTELT SGKVITGISK HMSVIQDAIG EKLGHFTSSC ATFFAGMVIA
TIACWEVALL CLVVVPLILL IGATYTKKMN RISTTKLFYH SEATSMIEQT ISQIKTVYAF
VGEGLAVKSF TENMDKQYVV SKGEALVKGV GTGMFQTVSF CSWSLIIWVG AVVVRAGRAQ
GGDIITAVMS ILFGAISITY AAPDMQIFNQ AKAAGYEVFQ VIQRKPLIHN ESKGKMPNKI
DGSIELRNVY FSYPSRSEKP ILQGLSLSIP AGKTVALVGS SGCGKSTAIS LITRFYDPTR
GEIFIDSHNI KDLDLKFLRS NIGAVYQEPS LFTGTIKDNL KLGKMDASDE EIQKAAVMSN
AHSFISQLPN QYLTEVGQRG VQVSGGQKQR IAIARAILKN PPILLLDEAT SALDSESEKL
VQEALDTAMQ GRTVILIAHR LSTVVNADMI AVVENGQIVE TGTHQSLLDT SKFYSTLFSM
QNLEPAPELR TTTSKDKSAR REDTIDETRP VPETQREVQR DLIEHSVLKE QNKTGTREEN
IFFRIWYDLK KKELVKIAIG SFAAAFSGIS KPFFGFYIIT IGVAYFQDDA KRKVGLFSAI
FSAIGLLSLF SHTFQHYFFG VVGEKAMANF RRALYSGVLC NEVGWFDKPE NTVGSLTSRI
ISDTSMVKII IADRMSVIVQ CVSSILIATG VSMYVNWRMA LVAWAVMPCH FIGGLIQAKS
AKGFSGDYSA THSDLVALAS ESTTNIRTIA SFCHEEQVLE KAKTYLDIPK KKYRKESIKY
GIIQGFSLCL WNIAHAVALW YTTILVDRRQ ASFENGIRAY QIFSLTVPSI TELYTLIPTV
ITAINMLTPA FKTLDRKTEI EPDIPDDSQP DRIQGNVEFE NVNFKYPLRP TVTVLDNFSL
QIEAGSKVAF VGPSGAGKSS VLALLLRFYD PVVGKVLIDG KDLREYNLRW LRTQIGLVQQ
EPLLFNCSIR ENICYGNNGA FESEIVEVAR EANIHEFVSN LPNGYNTVVG EKGCQLSGGQ
KQRIAIARTL LKKPAILLLD EATSALDAES ERTIVNAIKA MNLKEETGLR SRITQITVAH
RLSTVRNSDT IIVMEKGKIV ETGSHSTLIE VDAGLYSRLF RLQSFDETS
//
