ID G7JE66_MEDTR Unreviewed; 1134 AA.
AC G7JE66; A0A0C3X5Q2;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2014, sequence version 2.
DT 27-MAR-2024, entry version 75.
DE SubName: Full=Putative transcription factor WD40-like family {ECO:0000313|EMBL:RHN63974.1};
DE SubName: Full=Topless-like protein {ECO:0000313|EMBL:AES91574.2};
GN Name=11441233 {ECO:0000313|EnsemblPlants:AES91574};
GN OrderedLocusNames=MTR_4g114980 {ECO:0000313|EMBL:AES91574.2};
GN ORFNames=MtrunA17_Chr4g0064101 {ECO:0000313|EMBL:RHN63974.1};
OS Medicago truncatula (Barrel medic) (Medicago tribuloides).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; Hologalegina; IRL clade; Trifolieae; Medicago.
OX NCBI_TaxID=3880 {ECO:0000313|EMBL:AES91574.2, ECO:0000313|Proteomes:UP000002051};
RN [1] {ECO:0000313|EMBL:AES91574.2, ECO:0000313|Proteomes:UP000002051}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=A17 {ECO:0000313|EMBL:AES91574.2}, and cv. Jemalong A17
RC {ECO:0000313|EnsemblPlants:AES91574,
RC ECO:0000313|Proteomes:UP000002051};
RX PubMed=22089132; DOI=10.1038/nature10625;
RA Young N.D., Debelle F., Oldroyd G.E., Geurts R., Cannon S.B., Udvardi M.K.,
RA Benedito V.A., Mayer K.F., Gouzy J., Schoof H., Van de Peer Y., Proost S.,
RA Cook D.R., Meyers B.C., Spannagl M., Cheung F., De Mita S.,
RA Krishnakumar V., Gundlach H., Zhou S., Mudge J., Bharti A.K., Murray J.D.,
RA Naoumkina M.A., Rosen B., Silverstein K.A., Tang H., Rombauts S.,
RA Zhao P.X., Zhou P., Barbe V., Bardou P., Bechner M., Bellec A., Berger A.,
RA Berges H., Bidwell S., Bisseling T., Choisne N., Couloux A., Denny R.,
RA Deshpande S., Dai X., Doyle J.J., Dudez A.M., Farmer A.D., Fouteau S.,
RA Franken C., Gibelin C., Gish J., Goldstein S., Gonzalez A.J., Green P.J.,
RA Hallab A., Hartog M., Hua A., Humphray S.J., Jeong D.H., Jing Y.,
RA Jocker A., Kenton S.M., Kim D.J., Klee K., Lai H., Lang C., Lin S.,
RA Macmil S.L., Magdelenat G., Matthews L., McCorrison J., Monaghan E.L.,
RA Mun J.H., Najar F.Z., Nicholson C., Noirot C., O'Bleness M., Paule C.R.,
RA Poulain J., Prion F., Qin B., Qu C., Retzel E.F., Riddle C., Sallet E.,
RA Samain S., Samson N., Sanders I., Saurat O., Scarpelli C., Schiex T.,
RA Segurens B., Severin A.J., Sherrier D.J., Shi R., Sims S., Singer S.R.,
RA Sinharoy S., Sterck L., Viollet A., Wang B.B., Wang K., Wang M., Wang X.,
RA Warfsmann J., Weissenbach J., White D.D., White J.D., Wiley G.B.,
RA Wincker P., Xing Y., Yang L., Yao Z., Ying F., Zhai J., Zhou L., Zuber A.,
RA Denarie J., Dixon R.A., May G.D., Schwartz D.C., Rogers J., Quetier F.,
RA Town C.D., Roe B.A.;
RT "The Medicago genome provides insight into the evolution of rhizobial
RT symbioses.";
RL Nature 480:520-524(2011).
RN [2] {ECO:0000313|EMBL:AES91574.2, ECO:0000313|Proteomes:UP000002051}
RP GENOME REANNOTATION.
RC STRAIN=cv. Jemalong A17 {ECO:0000313|EnsemblPlants:AES91574,
RC ECO:0000313|Proteomes:UP000002051};
RX PubMed=24767513; DOI=10.1186/1471-2164-15-312;
RA Tang H., Krishnakumar V., Bidwell S., Rosen B., Chan A., Zhou S.,
RA Gentzbittel L., Childs K.L., Yandell M., Gundlach H., Mayer K.F.,
RA Schwartz D.C., Town C.D.;
RT "An improved genome release (version Mt4.0) for the model legume Medicago
RT truncatula.";
RL BMC Genomics 15:312-312(2014).
RN [3] {ECO:0000313|EnsemblPlants:AES91574}
RP IDENTIFICATION.
RC STRAIN=cv. Jemalong A17 {ECO:0000313|EnsemblPlants:AES91574};
RG EnsemblPlants;
RL Submitted (APR-2015) to UniProtKB.
RN [4] {ECO:0000313|EMBL:RHN63974.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaves {ECO:0000313|EMBL:RHN63974.1};
RA Pecrix Y., Gamas P., Carrere S.;
RT "Whole-genome landscape of Medicago truncatula symbiotic genes.";
RL Nat. Plants 0:0-0(2018).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CM001220; AES91574.2; -; Genomic_DNA.
DR EMBL; PSQE01000004; RHN63974.1; -; Genomic_DNA.
DR RefSeq; XP_003609377.2; XM_003609329.2.
DR AlphaFoldDB; G7JE66; -.
DR STRING; 3880.G7JE66; -.
DR PaxDb; 3880-AES91574; -.
DR EnsemblPlants; AES91574; AES91574; MTR_4g114980.
DR GeneID; 11441233; -.
DR Gramene; AES91574; AES91574; MTR_4g114980.
DR KEGG; mtr:11441233; -.
DR eggNOG; KOG0266; Eukaryota.
DR OrthoDB; 2508083at2759; -.
DR Proteomes; UP000002051; Chromosome 4.
DR Proteomes; UP000265566; Chromosome 4.
DR ExpressionAtlas; G7JE66; differential.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IBA:GO_Central.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 4.
DR InterPro; IPR006595; CTLH_C.
DR InterPro; IPR006594; LisH.
DR InterPro; IPR011047; Quinoprotein_ADH-like_supfam.
DR InterPro; IPR027728; Topless_fam.
DR InterPro; IPR048419; Topless_Znf.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR44083; TOPLESS-RELATED PROTEIN 1-RELATED; 1.
DR PANTHER; PTHR44083:SF35; WD_REPEATS_REGION DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00400; WD40; 3.
DR Pfam; PF21359; zf_topless; 1.
DR SMART; SM00668; CTLH; 1.
DR SMART; SM00667; LisH; 1.
DR SMART; SM00320; WD40; 11.
DR SUPFAM; SSF75011; 3-carboxy-cis,cis-mucoante lactonizing enzyme; 1.
DR SUPFAM; SSF50998; Quinoprotein alcohol dehydrogenase-like; 1.
DR PROSITE; PS50897; CTLH; 1.
DR PROSITE; PS50896; LISH; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 2.
DR PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000002051};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT DOMAIN 34..92
FT /note="CTLH"
FT /evidence="ECO:0000259|PROSITE:PS50897"
FT REPEAT 459..502
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 923..955
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 1101..1134
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1119..1134
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1134 AA; 125108 MW; 068D96D7D2B9881B CRC64;
MSSLSRELVF LILQFLDEEK FKESVHRLEQ ESGFFFNMRY FEEMVTNGEW DEVEKYLTGF
TKVDDNRYSM KIFFEIRKQK YLEALDKGDR SKAVEILVKD LKVFAAFNEE LFKEITQLLT
LDNFRQNEQL SKYGDTKSAR GIMLAELKKL IEANPLFRDK LQFPSLKNSR LRTLINQSLN
WQHQLCKNPR PNPDIKTLFV DHSCGQPNGA RAPSPVTNPL MAGVPKVGGF PPLSAHGPFQ
PTPNALPTSL AGWMAASPQV QHPSASAGVG PIGLAQANNP ALLKRPRTPP NNPAMDYQTA
DSDHVMKRTR PFGISDEVNN LPVNLLPVAY SSQSHGQSSY SSDDLPKTAV MTLNQGSTVK
SMDFHPLQQI LLLVGTNMGD VMVWDIGSRE RIAHRSFKVW DLQVCSVALQ ASLSNEYSAS
VNRVVWSPDG TLCSVAYSKH IVHIYSYHGG DDLRNHLEIE AHAGSVNDLA FSYPNKQLCV
VTCGEDRVIK VWDAVTGAKQ YTFEGHEAPV YSVCPHHKEN IQFIFSTATD GKIKAWLYDN
MGSRVDYDAP GHSSTTMSYS ADGTRLFSCG TNKEGESFLV EWNESEGAVK RTYHGLGKRS
TGVVQFDTTK NRFLAAGDEF MVKFWDMDST NLLTSFDADG GLLASPCIRF NKEGILLAVS
TSDNGVKILA NAEGIRLLRT VENRAFDASR AASAANVKPP TIGAFPSTNV AVGTSLADRT
PPVAAMVGLN NDSRSLADVK PRIVDEAVEK SRIWKLTEIN EQSQCRSLKL PDGLSSMRVS
RLIYTNQGVA ILALAANAVH KLWKWQKNDR NTSGKATASL QPQLWQPSSG ILMTNEIGDT
NPEDAVSCFA LSKNDSYVMS ASGGKISLFN MMTFKTMTTF MPPPPAATFL AFHPQDNNII
AIGMDDSSIQ IYNVRVDEVK TKLKGHQKRI TGLAFSHVLN ILVSSGADSQ LCVWSTDGWE
KQTNKFLQMP NGRALAPLAD TRVQFHLDQT HLLAVHETQI AIYEAPKLEC LKQWVPREAS
GPITHATYSC DSQSIYVSFE DGSIGVLTAS TLRLRCRINQ TAYLNPNPSL RVYPLVIAAH
PSESNQFALG LTDGGVHVLE PLESEGRWGS PPPTENGVGP STPSGASVSE QPQR
//
