ID G7JNQ7_MEDTR Unreviewed; 703 AA.
AC G7JNQ7; A0A0C3X4D8;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2014, sequence version 2.
DT 27-MAR-2024, entry version 60.
DE SubName: Full=Putative initiation factor eIF-4 gamma, MA3 {ECO:0000313|EMBL:RHN63414.1};
DE SubName: Full=Topoisomerase-like protein {ECO:0000313|EMBL:AES91110.2};
GN Name=11407964 {ECO:0000313|EnsemblPlants:AES91110};
GN OrderedLocusNames=MTR_4g104360 {ECO:0000313|EMBL:AES91110.2};
GN ORFNames=MtrunA17_Chr4g0058021 {ECO:0000313|EMBL:RHN63414.1};
OS Medicago truncatula (Barrel medic) (Medicago tribuloides).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; Hologalegina; IRL clade; Trifolieae; Medicago.
OX NCBI_TaxID=3880 {ECO:0000313|EMBL:AES91110.2, ECO:0000313|Proteomes:UP000002051};
RN [1] {ECO:0000313|EMBL:AES91110.2, ECO:0000313|Proteomes:UP000002051}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=A17 {ECO:0000313|EMBL:AES91110.2}, and cv. Jemalong A17
RC {ECO:0000313|EnsemblPlants:AES91110,
RC ECO:0000313|Proteomes:UP000002051};
RX PubMed=22089132; DOI=10.1038/nature10625;
RA Young N.D., Debelle F., Oldroyd G.E., Geurts R., Cannon S.B., Udvardi M.K.,
RA Benedito V.A., Mayer K.F., Gouzy J., Schoof H., Van de Peer Y., Proost S.,
RA Cook D.R., Meyers B.C., Spannagl M., Cheung F., De Mita S.,
RA Krishnakumar V., Gundlach H., Zhou S., Mudge J., Bharti A.K., Murray J.D.,
RA Naoumkina M.A., Rosen B., Silverstein K.A., Tang H., Rombauts S.,
RA Zhao P.X., Zhou P., Barbe V., Bardou P., Bechner M., Bellec A., Berger A.,
RA Berges H., Bidwell S., Bisseling T., Choisne N., Couloux A., Denny R.,
RA Deshpande S., Dai X., Doyle J.J., Dudez A.M., Farmer A.D., Fouteau S.,
RA Franken C., Gibelin C., Gish J., Goldstein S., Gonzalez A.J., Green P.J.,
RA Hallab A., Hartog M., Hua A., Humphray S.J., Jeong D.H., Jing Y.,
RA Jocker A., Kenton S.M., Kim D.J., Klee K., Lai H., Lang C., Lin S.,
RA Macmil S.L., Magdelenat G., Matthews L., McCorrison J., Monaghan E.L.,
RA Mun J.H., Najar F.Z., Nicholson C., Noirot C., O'Bleness M., Paule C.R.,
RA Poulain J., Prion F., Qin B., Qu C., Retzel E.F., Riddle C., Sallet E.,
RA Samain S., Samson N., Sanders I., Saurat O., Scarpelli C., Schiex T.,
RA Segurens B., Severin A.J., Sherrier D.J., Shi R., Sims S., Singer S.R.,
RA Sinharoy S., Sterck L., Viollet A., Wang B.B., Wang K., Wang M., Wang X.,
RA Warfsmann J., Weissenbach J., White D.D., White J.D., Wiley G.B.,
RA Wincker P., Xing Y., Yang L., Yao Z., Ying F., Zhai J., Zhou L., Zuber A.,
RA Denarie J., Dixon R.A., May G.D., Schwartz D.C., Rogers J., Quetier F.,
RA Town C.D., Roe B.A.;
RT "The Medicago genome provides insight into the evolution of rhizobial
RT symbioses.";
RL Nature 480:520-524(2011).
RN [2] {ECO:0000313|EMBL:AES91110.2, ECO:0000313|Proteomes:UP000002051}
RP GENOME REANNOTATION.
RC STRAIN=A17 {ECO:0000313|EMBL:AES91110.2}, and cv. Jemalong A17
RC {ECO:0000313|EnsemblPlants:AES91110,
RC ECO:0000313|Proteomes:UP000002051};
RX PubMed=24767513; DOI=10.1186/1471-2164-15-312;
RA Tang H., Krishnakumar V., Bidwell S., Rosen B., Chan A., Zhou S.,
RA Gentzbittel L., Childs K.L., Yandell M., Gundlach H., Mayer K.F.,
RA Schwartz D.C., Town C.D.;
RT "An improved genome release (version Mt4.0) for the model legume Medicago
RT truncatula.";
RL BMC Genomics 15:312-312(2014).
RN [3] {ECO:0000313|EnsemblPlants:AES91110}
RP IDENTIFICATION.
RC STRAIN=cv. Jemalong A17 {ECO:0000313|EnsemblPlants:AES91110};
RG EnsemblPlants;
RL Submitted (APR-2015) to UniProtKB.
RN [4] {ECO:0000313|EMBL:RHN63414.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaves {ECO:0000313|EMBL:RHN63414.1};
RA Pecrix Y., Gamas P., Carrere S.;
RT "Whole-genome landscape of Medicago truncatula symbiotic genes.";
RL Nat. Plants 0:0-0(2018).
CC -!- SIMILARITY: Belongs to the PDCD4 family.
CC {ECO:0000256|ARBA:ARBA00005497}.
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DR EMBL; CM001220; AES91110.2; -; Genomic_DNA.
DR EMBL; PSQE01000004; RHN63414.1; -; Genomic_DNA.
DR RefSeq; XP_003608913.2; XM_003608865.2.
DR AlphaFoldDB; G7JNQ7; -.
DR STRING; 3880.G7JNQ7; -.
DR PaxDb; 3880-AES91110; -.
DR EnsemblPlants; AES91110; AES91110; MTR_4g104360.
DR GeneID; 11407964; -.
DR Gramene; AES91110; AES91110; MTR_4g104360.
DR KEGG; mtr:11407964; -.
DR eggNOG; KOG0403; Eukaryota.
DR HOGENOM; CLU_013764_0_0_1; -.
DR OrthoDB; 1217702at2759; -.
DR Proteomes; UP000002051; Chromosome 4.
DR Proteomes; UP000265566; Chromosome 4.
DR ExpressionAtlas; G7JNQ7; differential.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
DR GO; GO:0045892; P:negative regulation of DNA-templated transcription; IEA:InterPro.
DR Gene3D; 1.25.40.180; -; 4.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR003891; Initiation_fac_eIF4g_MI.
DR InterPro; IPR039778; PDCD4.
DR PANTHER; PTHR12626; PROGRAMMED CELL DEATH 4; 1.
DR PANTHER; PTHR12626:SF0; PROGRAMMED CELL DEATH PROTEIN 4; 1.
DR Pfam; PF02847; MA3; 4.
DR SMART; SM00544; MA3; 4.
DR SUPFAM; SSF48371; ARM repeat; 4.
DR PROSITE; PS51366; MI; 4.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Initiation factor {ECO:0000313|EMBL:RHN63414.1};
KW Protein biosynthesis {ECO:0000313|EMBL:RHN63414.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000002051};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Translation regulation {ECO:0000256|ARBA:ARBA00022845}.
FT DOMAIN 122..243
FT /note="MI"
FT /evidence="ECO:0000259|PROSITE:PS51366"
FT DOMAIN 286..407
FT /note="MI"
FT /evidence="ECO:0000259|PROSITE:PS51366"
FT DOMAIN 420..541
FT /note="MI"
FT /evidence="ECO:0000259|PROSITE:PS51366"
FT DOMAIN 583..702
FT /note="MI"
FT /evidence="ECO:0000259|PROSITE:PS51366"
FT REGION 1..34
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 64..83
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 15..34
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 703 AA; 77497 MW; 2CF8741DB1D4B505 CRC64;
MASNEGFLTE GQREMLKIAS QNAENLSTSP KSPSTLLADH HHIKAPAGGK AQTAGIAVRH
VRRSHSGKLG RAKKDGAGGK GTWGKLLDTE VDSHIDRNDP NYDSGEEPYE LVGTTVTDPL
DEFKKAVVSL IDEYFSNGDV DLAASDLREL GSSEYYPYFI KRLVSMAMDR HDKEKEMASV
LLSALYADVI SPTQIRDGFF MLIESADDLA VDILDAVDIL ALFLARAVVD DILPPAFLAR
ARKALPESSK GAQVVQTAEK SYLSAPHHAE LVERRWGGST HITVEEMKKK IADLLKEYVD
SGETLEACRC IRELGVAFFH HEVVKKALVL AMEIPSAEPL LLKLLKEAAA EGLISSSQMV
KGFSRLEEGL DDLALDIPSA KALFQSFVPK AISEGWLDAS FDNPAGENGE FQVEDENVRK
YKKEAVTIIH EYFLSDDIPE LIRSLEDLGA PEYNPIFLKR LITLALDRKN REKEMASVLL
SALHIEIFST EDIVNGFVML LENAEDTTLD ILDASNELAL FLARAVIDDV LAPLNLDEIG
SRLPPKCSGS ETVRMARTLS SARHAGERLL RCWGGGTGWA VEDAKDKITK LLEEYESGGV
VGEACQCIRD LGMPFFNHEV VKKALVMAME KKNDRMLDLL QECFSEGLIT TNQLTKGFTR
IKEGLDDLAL DIPNAKEKFA FYVEHAKTKG WLLPSFDSSA PDV
//
