ID G7L0I6_MEDTR Unreviewed; 786 AA.
AC G7L0I6;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 27-MAR-2024, entry version 63.
DE SubName: Full=Nucleolar MIF4G domain protein {ECO:0000313|EMBL:AES80894.1};
GN Name=11440086 {ECO:0000313|EnsemblPlants:AES80894};
GN OrderedLocusNames=MTR_7g086290 {ECO:0000313|EMBL:AES80894.1};
OS Medicago truncatula (Barrel medic) (Medicago tribuloides).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; Hologalegina; IRL clade; Trifolieae; Medicago.
OX NCBI_TaxID=3880 {ECO:0000313|EMBL:AES80894.1, ECO:0000313|Proteomes:UP000002051};
RN [1] {ECO:0000313|EMBL:AES80894.1, ECO:0000313|Proteomes:UP000002051}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=A17 {ECO:0000313|EMBL:AES80894.1}, and cv. Jemalong A17
RC {ECO:0000313|EnsemblPlants:AES80894,
RC ECO:0000313|Proteomes:UP000002051};
RX PubMed=22089132; DOI=10.1038/nature10625;
RA Young N.D., Debelle F., Oldroyd G.E., Geurts R., Cannon S.B., Udvardi M.K.,
RA Benedito V.A., Mayer K.F., Gouzy J., Schoof H., Van de Peer Y., Proost S.,
RA Cook D.R., Meyers B.C., Spannagl M., Cheung F., De Mita S.,
RA Krishnakumar V., Gundlach H., Zhou S., Mudge J., Bharti A.K., Murray J.D.,
RA Naoumkina M.A., Rosen B., Silverstein K.A., Tang H., Rombauts S.,
RA Zhao P.X., Zhou P., Barbe V., Bardou P., Bechner M., Bellec A., Berger A.,
RA Berges H., Bidwell S., Bisseling T., Choisne N., Couloux A., Denny R.,
RA Deshpande S., Dai X., Doyle J.J., Dudez A.M., Farmer A.D., Fouteau S.,
RA Franken C., Gibelin C., Gish J., Goldstein S., Gonzalez A.J., Green P.J.,
RA Hallab A., Hartog M., Hua A., Humphray S.J., Jeong D.H., Jing Y.,
RA Jocker A., Kenton S.M., Kim D.J., Klee K., Lai H., Lang C., Lin S.,
RA Macmil S.L., Magdelenat G., Matthews L., McCorrison J., Monaghan E.L.,
RA Mun J.H., Najar F.Z., Nicholson C., Noirot C., O'Bleness M., Paule C.R.,
RA Poulain J., Prion F., Qin B., Qu C., Retzel E.F., Riddle C., Sallet E.,
RA Samain S., Samson N., Sanders I., Saurat O., Scarpelli C., Schiex T.,
RA Segurens B., Severin A.J., Sherrier D.J., Shi R., Sims S., Singer S.R.,
RA Sinharoy S., Sterck L., Viollet A., Wang B.B., Wang K., Wang M., Wang X.,
RA Warfsmann J., Weissenbach J., White D.D., White J.D., Wiley G.B.,
RA Wincker P., Xing Y., Yang L., Yao Z., Ying F., Zhai J., Zhou L., Zuber A.,
RA Denarie J., Dixon R.A., May G.D., Schwartz D.C., Rogers J., Quetier F.,
RA Town C.D., Roe B.A.;
RT "The Medicago genome provides insight into the evolution of rhizobial
RT symbioses.";
RL Nature 480:520-524(2011).
RN [2] {ECO:0000313|EMBL:AES80894.1, ECO:0000313|Proteomes:UP000002051}
RP GENOME REANNOTATION.
RC STRAIN=cv. Jemalong A17 {ECO:0000313|EnsemblPlants:AES80894,
RC ECO:0000313|Proteomes:UP000002051};
RX PubMed=24767513; DOI=10.1186/1471-2164-15-312;
RA Tang H., Krishnakumar V., Bidwell S., Rosen B., Chan A., Zhou S.,
RA Gentzbittel L., Childs K.L., Yandell M., Gundlach H., Mayer K.F.,
RA Schwartz D.C., Town C.D.;
RT "An improved genome release (version Mt4.0) for the model legume Medicago
RT truncatula.";
RL BMC Genomics 15:312-312(2014).
RN [3] {ECO:0000313|EnsemblPlants:AES80894}
RP IDENTIFICATION.
RC STRAIN=cv. Jemalong A17 {ECO:0000313|EnsemblPlants:AES80894};
RG EnsemblPlants;
RL Submitted (APR-2015) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC {ECO:0000256|ARBA:ARBA00004604}.
CC -!- SIMILARITY: Belongs to the CWC22 family.
CC {ECO:0000256|ARBA:ARBA00006856}.
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DR EMBL; CM001223; AES80894.1; -; Genomic_DNA.
DR RefSeq; XP_003624676.1; XM_003624628.2.
DR AlphaFoldDB; G7L0I6; -.
DR STRING; 3880.G7L0I6; -.
DR PaxDb; 3880-AES80894; -.
DR EnsemblPlants; AES80894; AES80894; MTR_7g086290.
DR GeneID; 11440086; -.
DR Gramene; AES80894; AES80894; MTR_7g086290.
DR KEGG; mtr:11440086; -.
DR eggNOG; KOG2141; Eukaryota.
DR OMA; FMVDILN; -.
DR OrthoDB; 5491616at2759; -.
DR Proteomes; UP000002051; Chromosome 7.
DR ExpressionAtlas; G7L0I6; differential.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005730; C:nucleolus; IBA:GO_Central.
DR GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR GO; GO:0042274; P:ribosomal small subunit biogenesis; IBA:GO_Central.
DR Gene3D; 1.25.40.180; -; 1.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR003891; Initiation_fac_eIF4g_MI.
DR InterPro; IPR003890; MIF4G-like_typ-3.
DR PANTHER; PTHR18034; CELL CYCLE CONTROL PROTEIN CWF22-RELATED; 1.
DR PANTHER; PTHR18034:SF4; NUCLEOLAR MIF4G DOMAIN-CONTAINING PROTEIN 1; 1.
DR Pfam; PF02847; MA3; 1.
DR Pfam; PF02854; MIF4G; 1.
DR SMART; SM00544; MA3; 1.
DR SMART; SM00543; MIF4G; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR PROSITE; PS51366; MI; 1.
PE 3: Inferred from homology;
KW Initiation factor {ECO:0000256|ARBA:ARBA00022540};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917};
KW Reference proteome {ECO:0000313|Proteomes:UP000002051};
KW Translation regulation {ECO:0000256|ARBA:ARBA00022845};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 356..381
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 402..427
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 585..701
FT /note="MI"
FT /evidence="ECO:0000259|PROSITE:PS51366"
FT REGION 1..115
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 169..239
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..21
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 58..72
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 73..101
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 192..206
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 786 AA; 88981 MW; 07EBFE1F382060F4 CRC64;
MVEQTAEKSR RERRKESRLA KNASKYQSWL QHHQKSEAIK RTNNQIPELK SETKLDQPVI
PSLINETQVV KRSKSSSNKK EASEECALSE DEIDAPVVRK VKKGSQKSSK KKNRVEMGLS
DISMAAQMDL ELERKLSKKL KVKEGKLRGF DDGLNMLFEG MPSADDLFGD MEGFDSDELP
SRKTKKSSSS KKRKLSKEEM ETEGPVEARI QDAVFEEVPD SGTSRKKKKD KKRKLSIQEQ
EDGAEDYAVC IDKPVESSGA DVTSGDVAAD VSEKKVIGKY IAPHLRGRAG NEPEEHTQIR
RRVRGLLNRI SESNVESITG ELSLIFQSVA RSVASQIMIE ETLASCSGGP RGNKQYAAVF
AAFVAGLACT VGIDFGAKFM ASFAKCFEDE YHKQDNLSLR NIALLLSYLC IFGVCSSDLI
FDFLIMLSKR LTEVDVAIIL TVLQSCGMKI RADDPAAMKT FIVNVQDTSN KMKASSGDGP
EKNNSKRMEF MLETIYDIKN NKKKAEEVNP RIKKWLQKLR VDDISIRGLT WSKLLDPDKK
GQWWLSGDMV SATDNVEEVA NKIDKDVAET QRMLQLAAAQ RMNTDSRRAI FCIIMSGEDY
IDAFEKLLRL ELPGKQDRDI MRVLVECCLQ EKVFNKYYTV LASKLCEHDK NHKFTLQFCL
WDHFKELESM ALLRSMHLAK FVAEMAASFT LSLAVLKTVD LSDITQLTPK RIMHFRILFE
AIFEYPETVV WKIFTRIAGT PELEGFRQGI EFFIKEYIVK ANKAASQKFK LVKRALNNIE
GVLMQE
//
